Reactome: A Curated Pathway Database

Highly calcium permeable nicotinic acetylcholine receptors (R-HSA-629597)

Species Homo sapiens

Summation

Nicotinic acetylcholine receptors exhibit high influx of Ca2+, the degree of Ca2+ permeability is dependent on the subunit composition; homomeric acetylcholine receptors containing aplha 7 subunits allow maximum Ca2+ influx followed by receptors containing alpha3 beta2 alpha5 or alpha3 beta4 alpha5.

Locations in the PathwayBrowser
Additional Information
Compartment cytosol , extracellular region , plasma membrane
Literature References
pubMedId Title Journal Year
14670366 Ca2+ permeability of nicotinic acetylcholine receptors Cell Calcium 2004