Reactome: A Curated Pathway Database

TNF(1-233)

Stable Identifier
R-HSA-66220
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
TNF-alpha, Tumor necrosis factor precursor (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (Cachectin), Tumor necrosis factor precursor, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
TNF, TNFA, TNFSF2
Chain
chain:1-233, chain:1-39, chain:1-35, chain:50-, chain:52-, chain:77-233
Reference Genes
Reference Transcript
Other Identifiers
 0002450619  11721577_at  17006659  17026267  17027794
 17030620  17033337  17035418  17038117  17040712
 1852_at  1A8M  1TNF  207113_s_at  259_s_at
 2902417  2902418  2902420  2902421  2902423
 2902424  2AZ5  2E7A  2TUN  2ZJC
 2ZPX  3ALQ  3IT8  3L9J  3WD5
 4G3Y  4TSV  4TWT  5TSW  7124
 8118142  8177983  8179263  A_14_P110091  A_14_P125975
 A_23_P376488  A_24_P50759  AAA36758  AAA61198  AAA61200
 AAC03542  AAD18091  AAF71992  AAH28148  AAL47581
 AAO21132  AB088112  AB103618  AB202113  ADV31546
 AF043342  AF098751  AF129756  AHJ25918  AHJ25919
 AHJ25920  AHJ25921  AHJ25922  AHJ25923  AHJ25924
 AHJ25925  AK314960  AY066019  AY214167  BA000025
 BAB63396  BAC54944  BAE78639  BAF31279  BAG37464
 BC028148  CAA25650  CAA26669  CAA75070  CAA78745
 CCDS4702  cg00710269  cg01360627  cg01569083  cg02137984
 cg03037030  cg06825478  cg09637172  cg12681001  cg19124225
 cg21370522  cg21467614  cg26729380  cg26736341  CH471081
 CTQ86082  EAX03424  ENSG00000204490  ENSG00000206439  ENSG00000223952
 ENSG00000228321  ENSG00000228849  ENSG00000230108  ENSG00000232810  ENSP00000365290
 ENSP00000372988  ENSP00000389490  ENSP00000389492  ENSP00000392858  ENSP00000398698
 ENSP00000410668  ENST00000376122  ENST00000383496  ENST00000412275  ENST00000420425
 ENST00000443707  ENST00000448781  ENST00000449264  EntrezGene:7124  g10835154_3p_a_at
 GE59636  HGNC:11892  HPA064998  HQ201306  Hs.241570
 ILMN_1728106  IPR002959  IPR006052  IPR006053  IPR008983
 IPR021184  KF887965  KF887966  KF887967  KF887968
 KF887969  KF887970  KF887971  KF887972  LN874317
 M10988  M16441  M26331  MIM:157300  MIM:191160
 MIM:600807  MIM:611162  NM_000594  NP_000585  PF00229
 PH_hs_0012958  PR01234  PR01235  Q5STB3  SM00207
 TC06000371.hg  TC06002714.hg  TC6_apd_hap1000036.hg  TC6_cox_hap2000067.hg  TC6_dbb_hap3000058.hg
 TC6_mann_hap4000059.hg  TC6_mcf_hap5000053.hg  TC6_qbl_hap6000058.hg  TC6_ssto_hap7000054.hg  TNF
 TNF-001  TNLG1F  uc003nui.5  UPI000000D745  X01394
 X02910  X02910_at  Y14768  Z15026
Participant Of
Other forms of this molecule
Inferred To
Cross References
RefSeq
UCSC human
ZINC_target
GeneCards
DOCK Blaster
PRO
HMDB_protein
Protein Data Bank
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.926 P19438 TNR1A_HUMAN 12
0.788 Q13546 RIPK1_HUMAN 8
0.725 Q13490 BIRC2_HUMAN 4
0.643 Q12933 TRAF2_HUMAN 6
0.643 Q9BYM8 HOIL1_HUMAN 5
0.641 Q8UYL3 Q8UYL3_9POXV 3
0.609 P20333 TNR1B_HUMAN 2
0.564 Q9Y6K9 NEMO_HUMAN 2
0.527 Q9H0F6 SHRPN_HUMAN 2
0.527 Q15628 TRADD_HUMAN 4
0.488 Q16623 STX1A_HUMAN 2
0.488 Q8N6L0 KASH5_HUMAN 2