Reactome: A Curated Pathway Database

TNF(1-233)

Stable Identifier
R-HSA-66220
Type
Protein
Species
Homo sapiens
Compartment
Synonyms
TNF-alpha, Tumor necrosis factor precursor (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (Cachectin), Tumor necrosis factor precursor, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
TNF, TNFA, TNFSF2
Chain
chain:1-233, chain:1-39, chain:1-35, chain:50-, chain:52-, chain:77-233
Reference Genes
Reference Transcript
Other Identifiers
 0002450619  11721577_at  17006659  17026267  17027794
 17030620  17033337  17035418  17038117  17040712
 1852_at  1A8M  1TNF  207113_s_at  259_s_at
 2AZ5  2E7A  2TUN  2ZJC  2ZPX
 3ALQ  3IT8  3L9J  3WD5  4G3Y
 4TSV  4TWT  5TSW  7124  8118142
 8177983  8179263  A_14_P110091  A_14_P125975  A_23_P376488
 A_24_P50759  AAA36758  AAA61198  AAA61200  AAC03542
 AAD18091  AAF71992  AAH28148  AAL47581  AAO21132
 AB088112  AB103618  AB202113  ADV31546  AF043342
 AF098751  AF129756  AHJ25918  AHJ25919  AHJ25920
 AHJ25921  AHJ25922  AHJ25923  AHJ25924  AHJ25925
 AK314960  AY066019  AY214167  BA000025  BAB63396
 BAC54944  BAE78639  BAF31279  BAG37464  BC028148
 CAA25650  CAA26669  CAA75070  CAA78745  CCDS4702
 CH471081  CTQ86082  EAX03424  ENSG00000204490  ENSG00000206439
 ENSG00000223952  ENSG00000228321  ENSG00000228849  ENSG00000230108  ENSG00000232810
 ENSP00000365290  ENSP00000372988  ENSP00000389490  ENSP00000389492  ENSP00000392858
 ENSP00000398698  ENSP00000410668  ENST00000376122  ENST00000383496  ENST00000412275
 ENST00000420425  ENST00000443707  ENST00000448781  ENST00000449264  EntrezGene:7124
 g10835154_3p_a_at  GE59636  HGNC:11892  HPA064998  HQ201306
 Hs.241570  ILMN_1728106  IPR002959  IPR006052  IPR006053
 IPR008983  IPR021184  KF887965  KF887966  KF887967
 KF887968  KF887969  KF887970  KF887971  KF887972
 LN874317  M10988  M16441  M26331  MIM:191160
 NM_000594  NP_000585  PF00229  PH_hs_0012958  PR01234
 PR01235  Q5STB3  SM00207  TNF  TNF-001
 TNFA  uc003nui.5  UPI000000D745  X01394  X02910
 X02910_at  Y14768  Z15026
Participant Of
Other forms of this molecule
Inferred To
Cross References
RefSeq
UCSC human
ZINC_target
GeneCards
DOCK Blaster
PRO
HMDB_protein
Protein Data Bank
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.926 P19438 TNR1A_HUMAN 12
0.788 Q13546 RIPK1_HUMAN 8
0.725 Q13490 BIRC2_HUMAN 4
0.643 Q12933 TRAF2_HUMAN 6
0.643 Q9BYM8 HOIL1_HUMAN 5
0.641 Q8UYL3 Q8UYL3_9POXV 3
0.609 P20333 TNR1B_HUMAN 2
0.564 Q9Y6K9 NEMO_HUMAN 2
0.527 Q9H0F6 SHRPN_HUMAN 2
0.527 Q15628 TRADD_HUMAN 4
0.488 Q16623 STX1A_HUMAN 2
0.488 Q8N6L0 KASH5_HUMAN 2