Reactome: A Curated Pathway Database

ERCC2 (R-HSA-67443) [Homo sapiens]

Reference Gene Product
Locations in the PathwayBrowser
Other forms of this molecule
Additional Information
External reference name ERCC2
External reference id P18074
Synonyms XPD protein, ERCC2/CXPD, TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) (DNA-repair protein complementing XP-D cells) (Xeroderma pigmentosum group D complementing protein) (CXPD) (DNA excision repair protein ERCC-2), TFIIH basal transcription factor complex helicase subunit , DNA-repair protein complementing XP-D cells, Xeroderma pigmentosum group D complementing protein, CXPD
Compartment nucleoplasm
Other Identifiers
 11735285_x_at  11750082_a_at  11754536_a_at  2068  213468_at
 235399_at  32396_f_at  32397_r_at  41095_at  63062_at
 992_at  A_23_P130488  A_24_P401990  AAI08256  AAI10524
 AAL48323  AAM45142  AAP35529  AY092780  B4E0F6
 BC108255  BC110523  BT006883  CAA36463  CAA36464
 CAB005375  CCDS33049  CCDS46112  CH471126  EAW57341
 ENSG00000104884  ENSP00000375809  ENSP00000431229  ENST00000391945  ENST00000485403
 EntrezGene:2068  ERCC2  ERCC2-001  ERCC2-006  GE59772
 HGNC:3434  HPA038057  Hs.184329.0.S1_3p_at  Hs.99987.0.S1_3p_at  IPR001945
 IPR002464  IPR006554  IPR006555  IPR010614  IPR010643
 IPR013020  IPR014013  IPR027417  L47234  LRG_461
 LRG_461t1  MIM:126340  NM_000400  NM_001130867  NP_000391
 NP_001124339  OTTHUMP00000045860  OTTHUMP00000267449  PF06733  PF06777
 PF13307  PH_hs_0005591  PR00852  R-HSA-112382  R-HSA-113418
 R-HSA-1430728  R-HSA-162587  R-HSA-162599  R-HSA-162906  R-HSA-1643685
 R-HSA-167152  R-HSA-167158  R-HSA-167160  R-HSA-167161  R-HSA-167162
 R-HSA-167169  R-HSA-167172  R-HSA-167200  R-HSA-167246  R-HSA-212165
 R-HSA-2564830  R-HSA-427413  R-HSA-504046  R-HSA-5250941  R-HSA-5663205
 R-HSA-5696395  R-HSA-5696398  R-HSA-5696399  R-HSA-5696400  R-HSA-674695
 R-HSA-6781823  R-HSA-6781827  R-HSA-6782135  R-HSA-6782210  R-HSA-72086
 R-HSA-73762  R-HSA-73772  R-HSA-73776  R-HSA-73777  R-HSA-73779
 R-HSA-73854  R-HSA-73857  R-HSA-73863  R-HSA-73864  R-HSA-73894
 R-HSA-74160  R-HSA-75953  R-HSA-75955  R-HSA-76042  R-HSA-77075
 SM00488  SM00491  uc002pbj.3  uc002pbl.6  UPI000006D9DE
 UPI0000139012  X52221  X52221_at  X52222  XM_011526611
Secondary Identifiers ERCC2_HUMAN, Q2TB78, Q2YDY2, Q7KZU6, Q8N721
Gene Names ERCC2, XPD, XPDC
Chain chain:1-760
This entry is a component of:
Reference Genes
Database Identifier
dbSNP Gene 2068
CTD Gene 2068
BioGPS Gene 2068
NCBI Gene 2068
ENSEMBL ENSG00000104884
Orphanet 15989
Reference Transcripts
Database Identifier
RefSeq NM_000400
Cross References
Database Identifier
RefSeq NP_000391, NP_001124339
HMDB_protein HMDBP08717
PRO P18074
GeneCards P18074
UCSC human P18074
Inferred Entries
Inferred to
Confidence Score Interactor Accession Interactor Name Evidence
0.556 Q6P1K8 T2H2L_HUMAN 3