Reactome: A Curated Pathway Database

Phosphorylation and activation of Chk1 by ATM

Stable Identifier
R-HSA-69889
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

At the beginning of this reaction, 1 molecule of 'ATP', and 1 molecule of 'Chk1' are present. At the end of this reaction, 1 molecule of 'phospho-Chk1', and 1 molecule of 'ADP' are present.

This reaction takes place in the 'nucleus' and is mediated by the 'kinase activity' of 'phospho-ATM (Ser 1981)'.

Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
protein serine/threonine kinase activity of p-S1981,Ac-K3016-ATM [nucleoplasm] p-S1981,Ac-K3016-ATM [nucleoplasm] protein serine/threonine kinase activity (0004674)
Inferred From