Reactome: A Curated Pathway Database
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Transcriptional activation of cell cycle inhibitor p21

Stable Identifier
R-HSA-69895
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Both p53-independent and p53-dependent mechanisms of induction of p21 mRNA have been demonstrated. p21 is transcriptionally activated by p53 after DNA damage (el-Deiry et al., 1993).

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
Orthologous Events
Cross References