Cytosolic phosphogluconate dehydrogenase (PGD) catalyzes the reaction of 6-phospho-D-gluconate and NADP+ to form D-ribulose 5-phosphate, CO2, and NADPH + H+ (Beutler and Kuhl 1985; Rippa et al. 1998). The PGD enzyme is dimeric (Dallocchio et al. 1985).
|PGD dimer||phosphogluconate dehydrogenase (decarboxylating) activity (0004616)|
|3932573||Limiting role of 6-phosphogluconolactonase in erythrocyte hexose monophosphate pathway metabolism||J Lab Clin Med||1985|
|3994686||Half-site reactivity in 6-phosphogluconate dehydrogenase from human erythrocytes||Biochem J||1985|
|9920387||6-Phosphogluconate dehydrogenase: the mechanism of action investigated by a comparison of the enzyme from different species||Biochim Biophys Acta||1998|