Reactome: A Curated Pathway Database

xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate

Stable Identifier
R-HSA-71335
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Cytosolic transketolase catalyzes the reaction of D-erythrose 4-phosphate and D-xylulose 5-phosphate to form D-glyceraldehyde 3-phosphate and D-fructose 6-phosphate. The active transketolase enzyme is a homodimer with one molecule of thiamine pyrophosphate and magnesium bound to each monomer (Wang et al. 1997).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
transketolase activity of transketolase dimer [cytosol] transketolase dimer [cytosol] transketolase activity (0004802)
Orthologous Events