Reactome: A Curated Pathway Database

xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate (R-HSA-71335) [Homo sapiens]


Cytosolic transketolase catalyzes the reaction of D-erythrose 4-phosphate and D-xylulose 5-phosphate to form D-glyceraldehyde 3-phosphate and D-fructose 6-phosphate. The active transketolase enzyme is a homodimer with one molecule of thiamine pyrophosphate and magnesium bound to each monomer (Wang et al. 1997).

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Catalyst Activity
PhysicalEntity Activity Active Units
transketolase dimer transketolase activity (0004802)  
Inferred Entries
Orthologous events