Reactome: A Curated Pathway Database

D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate

Stable Identifier
R-HSA-71496
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Cytosolic aldolase catalyzes the cleavage of D-fructose 1,6-bisphosphate to yield dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate. The active form of aldolase is a homotetramer. Three aldolase isozymes have been identified which differ in their patterns of expression in various adult tissues and during development but are otherwise functionally indistinguishable (Ali and Cox 1995; Freemont et al. 1984, 1988).

Literature References
Participants
Participant Of
hasEvent
This entity is regulated by:
Title Physical Entity Activity
fructose-bisphosphate aldolase activity of aldolase tetramer [cytosol] aldolase tetramer [cytosol] fructose-bisphosphate aldolase activity (0004332)
Orthologous Events