Reactome: A Curated Pathway Database

3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate

Stable Identifier
R-HSA-71654
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Cytosolic phosphoglycerate mutase catalyzes the reversible isomerisation of 3- and 2-phosphoglycerate. The active form of the enzyme is a dimer. There are two isoforms of this enzyme, PGAM1 (isoform B, widely expressed in non-muscle tissue) and PGAM2 (isoform M, expressed in muscle) (Blouquit et al. 1988; Omenn and Cheung 1974; Repiso et al. 2005; Tsujino et al. 1993).

Literature References
Participants
Participant Of
hasEvent
This entity is regulated by:
Title Physical Entity Activity
phosphoglycerate mutase activity of phosphoglycerate mutase dimer [cytosol] phosphoglycerate mutase dimer [cytosol] phosphoglycerate mutase activity (0004619)
Orthologous Events