Reactome: A Curated Pathway Database

3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate (R-HSA-71654) [Homo sapiens]


Cytosolic phosphoglycerate mutase catalyzes the reversible isomerisation of 3- and 2-phosphoglycerate. The active form of the enzyme is a dimer. There are two isoforms of this enzyme, PGAM1 (isoform B, widely expressed in non-muscle tissue) and PGAM2 (isoform M, expressed in muscle) (Blouquit et al. 1988; Omenn and Cheung 1974; Repiso et al. 2005; Tsujino et al. 1993).

Additional Information
Compartment cytosol
Reverse Reaction 2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
phosphoglycerate mutase dimer phosphoglycerate mutase activity (0004619)