mRNA Splicing

Stable Identifier
R-HSA-72172
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The process in which excision of introns from the primary transcript of messenger RNA (mRNA) is followed by ligation of the two exon termini exposed by removal of each intron, is called mRNA splicing. Most of the mRNA is spliced by the major pathway, involving the U1, U2, U4, U5 and U6 snRNPs. A minor fraction, about 1 %, of the mRNAs are spliced via the U12 dependent pathway.

Literature References
PubMed ID Title Journal Year
12226669 Comprehensive proteomic analysis of the human spliceosome. Nature 2002
Participants
Participant Of
Event Information
Go Biological Process
Orthologous Events