The translation initiation complex forms when the 43S complex binds the mRNA that is associated with eIF4F, eIF4B and eIF4H. eIF4G in the eIF4F complex can directly contact eIF3 in the 43S complex. eIF1A is necessary for the formation of this complex.
|641056||The mechanism of action of protein synthesis initiation factors from rabbit reticulocytes.||J Biol Chem||1978|
|592399||Initiation of mammalian protein synthesis. II. The assembly of the initiation complex with purified initiation factors.||J Mol Biol||1978|
|6853548||New initiation factor activity required for globin mRNA translation.||J Biol Chem||1983|
|9732867||Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons.||Nature||1999|