Reactome: A Curated Pathway Database

Translation initiation complex formation (R-HSA-72649) [Homo sapiens]

Pathway
Summation

The translation initiation complex forms when the 43S complex binds the mRNA that is associated with eIF4F, eIF4B and eIF4H. eIF4G in the eIF4F complex can directly contact eIF3 in the 43S complex. eIF1A is necessary for the formation of this complex.

Additional Information
Compartment cytosol