Reactome: A Curated Pathway Database

Formation of the ternary complex, and subsequently, the 43S complex (R-HSA-72695) [Homo sapiens]


Binding of the methionyl-tRNA initiator to the active eIF2:GTP complex results in the formation of the ternary complex. Subsequently, this Met-tRNAi:eIF2:GTP (ternary) complex binds to the complex formed by the 40S subunit, eIF3 and eIF1A, to form the 43S complex.

Additional Information
Compartment cytosol
Inferred Entries
Orthologous events