Reactome: A Curated Pathway Database

Formation of the ternary complex, and subsequently, the 43S complex

Stable Identifier
R-HSA-72695
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Binding of the methionyl-tRNA initiator to the active eIF2:GTP complex results in the formation of the ternary complex. Subsequently, this Met-tRNAi:eIF2:GTP (ternary) complex binds to the complex formed by the 40S subunit, eIF3 and eIF1A, to form the 43S complex.

Literature References
Participants
Participant Of
Orthologous Events