Reactome: A Curated Pathway Database

Formation of the ternary complex, and subsequently, the 43S complex (R-HSA-72695)

Species Homo sapiens

Summation

Binding of the methionyl-tRNA initiator to the active eIF2:GTP complex results in the formation of the ternary complex. Subsequently, this Met-tRNAi:eIF2:GTP (ternary) complex binds to the complex formed by the 40S subunit, eIF3 and eIF1A, to form the 43S complex.

Locations in the PathwayBrowser
Additional Information
Compartment cytosol
Inferred Entries
Orthologous events