Reactome: A Curated Pathway Database

PRPS1

Stable Identifier
R-HSA-73483
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
phosphoribosyl pyrophosphate synthetase 1, Ribose-phosphate pyrophosphokinase I (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase I) (PPRibP) (PRS-I), Ribose-phosphate pyrophosphokinase I , Phosphoribosyl pyrophosphate synthetase I, PPRibP, PRS-I
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
PRPS1
Chain
initiator methionine:1, chain:2-318
Reference Genes
Reference Transcript
Other Identifiers
 00030+2.7.6.1  0006040717  00230+2.7.6.1  11717084_a_at  11717085_a_at
 17106031  208447_s_at  209440_at  2H06  2H07
 2H08  2HCR  3189073  3189077  36489_at
 36490_s_at  3986515  3986516  3986517  3986518
 3986521  3986524  3986525  3986527  3986528
 3986529  3EFH  3S5J  4F8E  4LYG
 4LZN  4LZO  4M0P  4M0U  5631
 8169240  A_23_P95764  AAH01605  AK297968  AK312706
 AL137787  AL772400  B7ZB02  BAA00733  BAG35584
 BAG60278  BC001605  CAA33386  CAI41098  CAI42173
 CCDS14529  CH471120  D00860  D00860_at  EAX02709
 EAX02710  EAX02711  ENSG00000147224  ENSP00000361512  ENST00000372435
 EntrezGene:5631  g12804406_3p_at  g4506126_3p_a_at  GE57039  GE57982
 GO:0000166  GO:0000287  GO:0002189  GO:0003674  GO:0004749
 GO:0005515  GO:0005524  GO:0005575  GO:0005622  GO:0005623
 GO:0005737  GO:0005829  GO:0006015  GO:0006144  GO:0006164
 GO:0006167  GO:0006221  GO:0007399  GO:0008150  GO:0009058
 GO:0009116  GO:0009156  GO:0009165  GO:0016208  GO:0016301
 GO:0016310  GO:0016740  GO:0019003  GO:0019693  GO:0030246
 GO:0031100  GO:0034418  GO:0034641  GO:0042802  GO:0042803
 GO:0043167  GO:0043234  GO:0043531  GO:0044249  GO:0044281
 GO:0046101  GO:0046872  GO:0048856  HGNC:9462  Hs.56
 ILMN_1667050  IPR000842  IPR005946  IPR029057  IPR029099
 LRG_264  LRG_264t1  MIM:300661  MIM:301835  MIM:311070
 MIM:311850  NM_002764  NP_002755  PF13793  PF14572
 PH_hs_0000008  PRPS1  PRPS1-204  SM01400  TC0X000526.hg
 uc004ene.5  UPI00000000A5  X15331  X15331_s_at
Participant Of
hasComponent
Inferred To
Cross References
UCSC human
GeneCards
DOCK Blaster
ZINC target
PRO
Orphanet
HMDB Protein
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.841 Q14558 KPRA_HUMAN 11
0.817 P60891 PRPS1_HUMAN 7
0.764 Q9NZD8 SPG21_HUMAN 6
0.666 P11908 PRPS2_HUMAN 6
0.621 Q9H8Y8 GORS2_HUMAN 3
0.621 O60256 KPRB_HUMAN 5
0.556 P32895 KPR1_YEAST 3
0.556 P38340 NTM1_YEAST 3
0.556 P11908-2 PRPS2 3