Reactome: A Curated Pathway Database

PRPS1

Stable Identifier
R-HSA-73483
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
phosphoribosyl pyrophosphate synthetase 1, Ribose-phosphate pyrophosphokinase I (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase I) (PPRibP) (PRS-I), Ribose-phosphate pyrophosphokinase I , Phosphoribosyl pyrophosphate synthetase I, PPRibP, PRS-I
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
PRPS1
Chain
initiator methionine:1, chain:2-318
Reference Genes
Reference Transcript
Other Identifiers
 00030+2.7.6.1  0006040717  00230+2.7.6.1  11717084_a_at  11717085_a_at
 17106031  208447_s_at  209440_at  2H06  2H07
 2H08  2HCR  3189073  3189077  36489_at
 36490_s_at  3986515  3986516  3986517  3986518
 3986521  3986524  3986525  3986527  3986528
 3986529  3EFH  3S5J  4F8E  4LYG
 4LZN  4LZO  4M0P  4M0U  5631
 8169240  A_23_P95764  AAH01605  AK297968  AK312706
 AL137787  AL772400  B7ZB02  BAA00733  BAG35584
 BAG60278  BC001605  CAA33386  CAI41098  CAI42173
 CCDS14529  CH471120  D00860  D00860_at  EAX02709
 EAX02710  EAX02711  ENSG00000147224  ENSP00000361512  ENST00000372435
 g12804406_3p_at  g4506126_3p_a_at  GE57039  GE57982  GO:0000166
 GO:0000287  GO:0002189  GO:0003674  GO:0004749  GO:0005515
 GO:0005524  GO:0005575  GO:0005622  GO:0005623  GO:0005737
 GO:0005829  GO:0006015  GO:0006144  GO:0006164  GO:0006167
 GO:0006221  GO:0007399  GO:0008150  GO:0009058  GO:0009116
 GO:0009156  GO:0009165  GO:0016208  GO:0016301  GO:0016310
 GO:0016740  GO:0019003  GO:0019693  GO:0030246  GO:0031100
 GO:0034418  GO:0034641  GO:0042802  GO:0042803  GO:0043167
 GO:0043234  GO:0043531  GO:0044249  GO:0044281  GO:0046101
 GO:0046872  GO:0048856  HGNC:9462  Hs.56  ILMN_1667050
 IPR000842  IPR005946  IPR029057  IPR029099  LRG_264
 LRG_264t1  MIM:300661  MIM:301835  MIM:311070  MIM:311850
 NCBI Gene:5631  NM_002764  NP_002755  PF13793  PF14572
 PH_hs_0000008  PRPS1  PRPS1-204  SM01400  TC0X000526.hg
 uc004ene.5  UPI00000000A5  X15331  X15331_s_at
Participant Of
hasComponent
Inferred To
Cross References
RefSeq
ZINC - Metabolites
UCSC human
ZINC - World Drugs
ZINC - FDA approved
GeneCards
ZINC - Substances
DOCK Blaster
ZINC - Biogenic
PRO
HMDB_protein
Protein Data Bank
ZINC - Predictions - Purchasable
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.841 Q14558 KPRA_HUMAN 11
0.817 P60891 PRPS1_HUMAN 7
0.764 Q9NZD8 SPG21_HUMAN 6
0.666 P11908 PRPS2_HUMAN 6
0.621 Q9H8Y8 GORS2_HUMAN 3
0.621 O60256 KPRB_HUMAN 5
0.556 P32895 KPR1_YEAST 3
0.556 P38340 NTM1_YEAST 3
0.556 P11908-2 PRPS2 3