Reactome: A Curated Pathway Database

Loss of Rrn3 from RNA Polymerase I promoter escape complex (R-HSA-73769)

Species Homo sapiens

Summation

Upon transcription initiation it is thought that RRN3 is inactivated and dissociates from the Loss of Rrn3 from the RNA Polymerase I promoter escape complex. SL1 and UBF are thought to remain bound to the promoter for multiple rounds of transcription initiation

Locations in the PathwayBrowser
Additional Information
Compartment nucleoplasm
Literature References
pubMedId Title Journal Year
12646563 Rrn3 becomes inactivated in the process of ribosomal DNA transcription. J Biol Chem 2003