There will be a maintenance on OICR IT systems starting Friday Dec 15 at 6PM EST until midnight Sunday Dec 17; Reactome will be affected by this downtime

Service under maintenance from Friday Dec 15 at 6PM EST until midnight Sunday Dec 17

Loss of Rrn3 from RNA Polymerase I promoter escape complex

Stable Identifier
R-HSA-73769
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Upon transcription initiation it is thought that RRN3 is inactivated and dissociates from the Loss of Rrn3 from the RNA Polymerase I promoter escape complex. SL1 and UBF are thought to remain bound to the promoter for multiple rounds of transcription initiation

Literature References
PubMed ID Title Journal Year
12646563 Rrn3 becomes inactivated in the process of ribosomal DNA transcription. J Biol Chem 2003
Participants
Participant Of
Orthologous Events