RNA Polymerase I Chain Elongation

Stable Identifier
R-HSA-73777
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The assembly of the initiation complex on the promoter and the transition from a closed to an open complex is then followed by promoter clearance and transcription elongation by RNA Pol I. Unlike the RNA polymerase II system, RNA polymerase I transcription does not require a form of energy such as ATP for initiation and elongation. Regulatory mechanisms operating at both the level of transcription initiation and elongation probably concurrently to adjust the level of rRNA synthesis to the need of the cell.

Literature References
PubMed ID Title Journal Year
14969726 Mechanism of RNA polymerase I transcription Adv. Protein Chem. 2004
Participants
Participant Of
Event Information
Orthologous Events