Reactome: A Curated Pathway Database

Recruitment of repair factors to form preincision complex (R-HSA-73936)

Species Homo sapiens

Summation

Transcription factor II H (TFIIH) and XPG are added to the damaged site on the DNA to form a pre-incision complex along with lesioned DNA template.

Locations in the PathwayBrowser
Additional Information
Compartment nucleoplasm
GO Biological Process nucleotide-excision repair, preincision complex assembly (0006294)
Literature References
pubMedId Title Journal Year
11511374 Sequential assembly of the nucleotide excision repair factors in vivo. Mol Cell 2001
10526214 Protein complexes in nucleotide excision repair. Mutat Res 1999