The cleavage of the damaged strand of DNA 5' to the site of damage occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision is carried out by ERCC1-XPF complex.
|GO Biological Process||nucleotide-excision repair, DNA incision, 5'-to lesion (0006296)|
|Incision complex with 3'-incised damaged DNA||endodeoxyribonuclease activity (0004520)|
|10214908||DNA damage recognition during nucleotide excision repair in mammalian cells.||Biochimie||1999|