Reactome: A Curated Pathway Database

Abortive initiation after formation of the first phosphodiester bond (R-HSA-73946)

Species Homo sapiens

Summation

At the beginning of this reaction, 1 molecule of 'pol II transcription complex' is present. At the end of this reaction, 1 molecule of 'TFIIA', 1 molecule of 'TFIIH', 1 molecule of 'TFIIE', 1 molecule of 'TFIID', 1 molecule of 'TFIIB', 1 molecule of 'RNA Polymerase II (unphosphorylated):TFIIF complex', and 1 molecule of 'template DNA with first transcript dinucleotide, opened to +8 position' are present.

This reaction takes place in the 'nucleus'.

Locations in the PathwayBrowser
Additional Information
Compartment nucleoplasm