Reactome: A Curated Pathway Database

Purine salvage (R-HSA-74217)

Species Homo sapiens

Summation

Nucleosides and free bases generated by DNA and RNA breakdown are converted back to nucleotide monophosphates, allowing them to re-enter the pathway of purine biosynthesis. Nucleosides and free bases generated by DNA breakdown are converted back to nucleotide monophosphates, allowing them to re-enter the pathway of purine biosynthesis. Nucleosides and free bases generated by RNA breakdown are converted back to nucleotide monophosphates, allowing them to re-enter the pathways of purine biosynthesis. Under normal conditions, DNA turnover is limited and deoxyribonucleotide salvage operates at a correspondingly low level (Watts 1974).

Locations in the PathwayBrowser
Additional Information
GO Biological Process purine-containing compound salvage (0043101)
Cross References
Database Identifier
BioModels Database BIOMD0000000015
Literature References
pubMedId Title Journal Year
4620886 Molecular variation in relation to purine metabolism J Clin Pathol Suppl (R Coll Pathol) 1974