Reactome: A Curated Pathway Database

Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (R-HSA-744887)

Species Homo sapiens

Summation

The role of the guanine nucleotide-binding protein G alpha-s subunit (G alpha-s) (Kozasa T et al, 1988) is to activate adenylate cyclase, which, in turn, produces cAMP, which, in turn, activates cAMP-dependent protein kinase.

Locations in the PathwayBrowser
Additional Information
Compartment plasma membrane