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Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs

Stable Identifier
R-HSA-744887
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The role of the guanine nucleotide-binding protein G alpha-s subunit (G alpha-s) (Kozasa T et al, 1988) is to activate adenylate cyclase, which, in turn, produces cAMP, which, in turn, activates cAMP-dependent protein kinase.

Literature References
Participants
Participant Of
Orthologous Events