Reactome: A Curated Pathway Database

Phosphorylation of IRS (R-HSA-74711)

Species Homo sapiens

Summation

At the beginning of this reaction, 1 molecule of 'ATP', and 1 molecule of 'IRS:activated insulin receptor' are present. At the end of this reaction, 1 molecule of 'phospho-IRS:activated insulin receptor', and 1 molecule of 'ADP' are present.

This reaction takes place on the 'internal side of plasma membrane' and is mediated by the 'transmembrane receptor protein tyrosine kinase activity' of 'IRS:activated insulin receptor'.

Locations in the PathwayBrowser
Additional Information
Compartment cytosol , plasma membrane