Reactome: A Curated Pathway Database

Insulin degradation

Stable Identifier
R-HSA-74730
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

At the beginning of this reaction, 1 molecule of 'insulin' is present.

This reaction takes place in the 'endosome' and is mediated by the 'insulysin activity of IDA (insulin degrading activity' of 'IDA (insulin degrading activity)'.

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
endopeptidase activity of IDA [endosome lumen] IDA [endosome lumen] endopeptidase activity (0004175)