Reactome: A Curated Pathway Database

Dephosphorylation of p-Y-IRS1,p-Y-IRS2 (R-HSA-74747)

Species Homo sapiens


At the beginning of this reaction, 1 molecule of 'phospho-IRS' is present. At the end of this reaction, 1 molecule of 'Orthophosphate', and 1 molecule of 'IRS' are present.

This reaction takes place in the 'cytosol' and is mediated by the 'protein tyrosine phosphatase activity' of 'protein tyrosine phosphatase'.

Locations in the PathwayBrowser
Additional Information
Compartment cytosol
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
protein tyrosine phosphatase protein tyrosine phosphatase activity (0004725)