Reactome: A Curated Pathway Database

p-Y-IRS1 (R-HSA-74772)

Species Homo sapiens

Locations in the PathwayBrowser
Developmental Biology(Homo sapiens)
Immune System(Homo sapiens)
Signal Transduction(Homo sapiens)

Other forms of this molecule

Additional Information
External reference name IRS1
External reference id P35568
Synonyms p-IRS1, Insulin receptor substrate-1
Compartment cytosol
Other Identifiers 0003850373, 11743627_a_at, 11743628_at, 11743629_at, 1IRS, 1K3A, 1QQG, 204686_at, 242979_at, 2Z8C, 3667, 41049_at, 75148_at, 850_r_at, 851_s_at, 872_i_at, A0A024R499, A_24_P225679, A_24_P802145, AAB21608, AAB27175, AAH53895, BC053895, CAB005261, CCDS2463, CH471063, EAW70838, EAW70839, ENSG00000169047, ENSP00000304895, ENST00000305123, EntrezGene:3667, g5031804_3p_at, GE58787, HGNC:6125, HPA046433, HPA050221, Hs.257786.0.A1_3p_at, Hs.471508, ILMN_1759232, IPR001849, IPR002404, IRS1, IRS1-001, MIM:125853, MIM:147545, NM_005544, NP_005535, OTTHUMP00000164234, PF00169, PF02174, PH_hs_0024522, PH_hs_0048800, PR00628, REACT_11061, REACT_111040, REACT_111102, REACT_111133, REACT_115596, REACT_115755, REACT_115871, REACT_115961, REACT_116008, REACT_116125, REACT_118638, REACT_118773, REACT_1195, REACT_12056, REACT_120736, REACT_12464, REACT_12578, REACT_147694, REACT_147723, REACT_147727, REACT_147814, REACT_150203, REACT_150210, REACT_150359, REACT_163769, REACT_163936, REACT_16888, REACT_169118, REACT_17025, REACT_21270, REACT_21272, REACT_268006, REACT_268269, REACT_268546, REACT_332, REACT_498, REACT_508, REACT_524, REACT_570, REACT_6802, REACT_6900, REACT_75774, REACT_75790, REACT_75829, REACT_762, REACT_9417, REACT_9470, REACT_976, S62539, S62539_at, S85963, SM00233, SM00310, uc002voh.4, UPI000003BB52, XM_005246534, XM_006712512, XP_005246591, XP_006712575
Secondary Identifiers IRS1_HUMAN
Gene Names IRS1
Chain chain:1-1242
This entry is a component of:
hasMember
Reference Genes
Database Identifier
dbSNP Gene 3667
CTD Gene 3667
BioGPS Gene 3667
NCBI Gene 3667
ENSEMBL ENSG00000169047
KEGG Gene 3667
OMIM 125853
Reference Transcripts
Database Identifier
RefSeq NM_005544
Cross References
Database Identifier
RefSeq NP_005535
DOCK Blaster 1K3A, 1IRS, 1QQG
PRO P35568
GeneCards P35568
UCSC human P35568
Protein Data Bank 1K3A, 1IRS, 1QQG
ModifiedResidues
Name Coordinate Modification PsiMod Name PsiMod Identifier PsiMod Definition
O4'-phospho-L-tyrosine at unknown position O4'-phospho-L-tyrosine 00048 A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.