Reactome: A Curated Pathway Database

Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box (R-HSA-74992) [Homo sapiens]

Reaction
Summation

PTRF binds the quaternary complex and mediates the dissociation of paused complex. PTRF interacts with the RNA polymerase I largest subunit (p194), TTF-I and the U-rich 3' end of the nascent pre-rRNA.

Additional Information
Compartment nucleoplasm