Reactome: A Curated Pathway Database

Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks (R-HSA-75177)

Species Homo sapiens

Summation

Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks involves the formation of RAD50:MRE11 complex, association of RAD50:MRE11 complex with NBS1 through MRE11 and association of the MRN with sites of DSB.

Locations in the PathwayBrowser
Additional Information
Compartment nucleoplasm