The type 1 promoters recruit TFIIIA, the founding member of the C2H2 zinc finger family of DNA-binding proteins (Engelke et al., 1980; Sakonju et al., 1981). The binding of TFIIIA then allows the binding of TFIIC (Lassar et al., 1983), a complex consisting of five subunits (which differs from the six subunits in S. cerevisiae) in human cells and S. pombe. Once the DNA/TFIIIA/TFIIIC complex is formed, Brf1-TFIIIB joins the complex and this in turn allows the recruitment of RNA polymerase III (Bieker et al., 1985; Setzer and Brown, 1985).
|3972795||Formation and stability of the 5 S RNA transcription complex||J Biol Chem||1985|
|3967290||Formation of a rate-limiting intermediate in 5S RNA gene transcription||Cell||1985|
|6153931||Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes||Cell||1980|
|7226225||The binding of a transcription factor to deletion mutants of a 5S ribosomal RNA gene||Cell||1981|
|6356356||Transcription of class III genes: formation of preinitiation complexes||Science||1983|