Dodecanoic acid (DDCX aka lauric acid) is a medium-chain fatty acid which serves as a model substrate for studying the CYP4A gene subfamily of cytochrome P450s. CYP4A11 and CYP2E1 are the principal isozymes involved in omega-hydroxylation and omega-1 hydroxylation respectively of DDCX.
|Compartment||smooth endoplasmic reticulum|
|GO Biological Process||fatty acid metabolic process (0006631)|
|Cytochrome P450 (CYP4A11 based)||oxygen binding (0019825)|
|8914854||Identification of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes||Arch Biochem Biophys||1996|