Reactome: A Curated Pathway Database

Capping complex formation

Stable Identifier
R-HSA-77077
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The capping enzyme binds the 5'-end of the nascent transcript soon after it is synthesized on the DNA template, and results in the formation of the capping complex along with the C-terminal domain of RNA polymerase II, and Spt5 (Heidemann et al. 2013, Buratowski 2009, Schoenberg and Maquat 2009).

Literature References
PubMed ID Title Journal Year
19729311 Re-capping the message Trends Biochem. Sci. 2009
22982363 Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription Biochim. Biophys. Acta 2013
19941815 Progression through the RNA polymerase II CTD cycle Mol. Cell 2009
24354960 Cap-binding complex (CBC) Biochem. J. 2014
Participants
Participant Of
hasEvent
Orthologous Events