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Utilization of Ketone Bodies

Stable Identifier
R-HSA-77108
Type
Pathway
Species
Homo sapiens
Compartment
Synonyms
Ketone body catabolism
Locations in the PathwayBrowser
Summation

The levels of acetone in ketone bodies are much lower than those of acetoacetic acid and beta-hydroxybutyric acid. Acetone cannot be converted back to acetyl-CoA, and is excreted in urine, or breathed out through the lungs. Extrahepatic tissues utilize ketone bodies by converting the beta-hydroxybutyrate successively to acetoacetate, acetoacetatyl-CoA, finally to acetyl-CoA (Sass 2011).

Literature References
PubMed ID Title Journal Year
21479626 Inborn errors of ketogenesis and ketone body utilization J Inherit Metab Dis 2011
Participants
Participant Of
Event Information
Orthologous Events
Cross References
BioModels Database