Utilization of Ketone Bodies

Stable Identifier
R-HSA-77108
Type
Pathway
Species
Homo sapiens
Compartment
Synonyms
Ketone body catabolism
ReviewStatus
5/5
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The levels of acetone in ketone bodies are much lower than those of acetoacetic acid and beta-hydroxybutyric acid. Acetone cannot be converted back to acetyl-CoA, and is excreted in urine, or breathed out through the lungs. Extrahepatic tissues utilize ketone bodies by converting the beta-hydroxybutyrate successively to acetoacetate, acetoacetatyl-CoA, finally to acetyl-CoA (Sass 2011).
Literature References
PubMed ID Title Journal Year
21479626 Inborn errors of ketogenesis and ketone body utilization

Sass, JO

J Inherit Metab Dis 2011
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Event Information
Orthologous Events
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