Reactome: A Curated Pathway Database

Insulin receptor recycling

Stable Identifier
R-HSA-77387
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Triggered by acidification of the endosome, insulin dissociates from the receptor and is degraded. The receptor is dephosphorylated and re-integrated into the plasma membrane, ready to be activated again by the binding of insulin molecules.

Participants
Participant Of
Orthologous Events
Cross References