Reactome: A Curated Pathway Database

Association of RAD51 with RAD52:DNA double-strand break ends (R-HSA-83642)

Species Homo sapiens

Summation

Binding of the RAD51:RAD52 complex to ssDNA may provide nucleation sites promoting the association of free RAD51 with the growing nucleoprotein filament. This interaction may also play a role in stimulating the strand transfer reactions mediated by RAD51 (Baumann, 1999).

Locations in the PathwayBrowser
Additional Information
Compartment nucleoplasm
Literature References
pubMedId Title Journal Year
10438626 Heteroduplex formation by human Rad51 protein: effects of DNA end-structure, hRP-A and hRad52. J Mol Biol 1999