Reactome: A Curated Pathway Database
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USP9X (FAM) deubiquitinates SMAD4

Stable Identifier
R-HSA-870437
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

USP9X (FAM) deubiquitinates SMAD4, thereby opposing the negative regulatory activity of TRIM33 (Ectodermin) (Dupont et al. 2009).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
thiol-dependent ubiquitinyl hydrolase activity of Ub-SMAD4:USP9X [cytosol] Ub-SMAD4:USP9X [cytosol] thiol-dependent ubiquitinyl hydrolase activity (0036459)
Orthologous Events