Reactome: A Curated Pathway Database

TRIM33 (Ectodermin) binds SMAD heterotrimer in the nucleus (R-HSA-870538) [Homo sapiens]


E3 ubiquitin protein ligase TRIM33 (also known as Ecto, Ectodermin or Tif1-gamma) binds to the SMAD heterotrimer, composed of SMAD4 and two phosphorylated R-SMADs (SMAD2 and/or SMAD3), in the nucleus (Dupont et al. 2009, Dupont et al. 2005, He et al. 2006).

Additional Information
Compartment nucleoplasm