Reactome: A Curated Pathway Database

Binding of STAT1 to p-IFNGR1 (R-HSA-873921)

Species Homo sapiens

Summation

The phosphorylated tyrosine residue 440 in the 440YDKPH444 motif on IFNGR1 chain serves as a docking site and recruits STAT1, an SH2 domain-containing transcription factor to the functional receptor unit.

Locations in the PathwayBrowser
Additional Information
Compartment cytosol , plasma membrane