Reactome: A Curated Pathway Database

Binding of STAT1 to p-IFNGR1

Stable Identifier
R-HSA-873921
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The phosphorylated tyrosine residue 440 in the 440YDKPH444 motif on IFNGR1 chain serves as a docking site and recruits STAT1, an SH2 domain-containing transcription factor to the functional receptor unit.

Literature References
Participants
Participant Of
Orthologous Events