Reactome: A Curated Pathway Database

TFAP2 (AP-2) family regulates transcription of other transcription factors

Stable Identifier
R-HSA-8866906
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Homodimers and possibly heterodimers of TFAP2A and TFAP2C, in complex with CITED2, stimulate transcription of the PITX2 gene, involved in left-right patterning and heart development (Bamforth et al. 2004, Li et al. 2012).

Literature References
Participants
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