Reactome: A Curated Pathway Database

Phosphorylated STAT5 is released

Stable Identifier
R-HSA-919404
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Deletion mutants have demonstrated that STAT dimerization can occur independently of the binding of 2 STAT molecules by a dimeric receptor. Although this does not exclude the possibility that STATs may dimerize while still associated with the receptor complex, dimerization is believe to occur following the release of phosphorylated monomers (e.g. Turkson & Jove 2000).

Literature References
Participants
Participant Of
Orthologous Events