Reactome: A Curated Pathway Database

SMG6 hydrolyzes mRNA with premature termination codon (R-HSA-927836)

Species Homo sapiens

Summation

SMG6 is an endoribonuclease which cleaves the mRNA bound by UPF1 near the premature termination codon (Glavan et al. 2006, Eberle et al. 2009).

Locations in the PathwayBrowser
Additional Information
Compartment cytosol