Reactome: A Curated Pathway Database

Chorismate via Shikimate Pathway (R-MTU-964903) [Mycobacterium tuberculosis]


The shikimate pathway leads to the biosynthesis of chorismate, which, in mycobacteria, is a precursor of aromatic amino acids, naphthoquinones, menaquinones and siderophores. The enzymes of this pathway are attractive pharmaceutical targets, as the pathway is absent from mammals, and there are no redundancies in it (Herrmann and Weaver, 1999).

Additional Information
Compartment cytosol
GO Biological Process chorismate biosynthetic process (0009423)
Literature References
pubMedId Title Journal Year
15012217 THE SHIKIMATE PATHWAY Annu Rev Plant Physiol Plant Mol Biol 1999