Reactome: A Curated Pathway Database

SNCA (R-HSA-976954) [Homo sapiens]

Reference Gene Product
Additional Information
External reference name SNCA
External reference id P37840
Synonyms Alpha-synuclein
Compartment extracellular region
Other Identifiers
 0004070292  0004730609  11731446_s_at  11731447_x_at  11731448_a_at
 11739782_a_at  11753730_a_at  11753731_x_at  11754090_a_at  1XQ8
 204466_s_at  204467_s_at  207827_x_at  211546_x_at  236081_at
 2JN5  2KKW  2M55  2X6M  37291_r_at
 3Q25  3Q26  3Q27  3Q28  3Q29
 44191_at  4BXL  4R0U  4R0W  4RIK
 4RIL  4ZNN  5CRW  6622  A_23_P29939
 A_32_P109653  AAA16117  AAA98487  AAA98493  AAC02114
 AAG30302  AAG30303  AAH13293  AAI08276  AAL15443
 AAY88735  AF163864  AFA25669  AFA25671  AFA25672
 AFA25674  AFA25675  AFA25677  AFA25678  AK290169
 AY049786  BAA06625  BAF82858  BC013293  BC108275
 CAB010877  CAG33339  CCDS3634  CCDS43252  CH471057
 CR457058  D31839  DQ088379  EAX06035  EAX06036
 ENSG00000145335  ENSP00000338345  ENSP00000343683  ENSP00000378437  ENSP00000378440
 ENSP00000378442  ENSP00000396241  ENSP00000421485  ENSP00000422238  ENSP00000426955
 ENSP00000484044  ENST00000336904  ENST00000345009  ENST00000394986  ENST00000394989
 ENST00000394991  ENST00000420646  ENST00000505199  ENST00000506244  ENST00000508895
 ENST00000618500  EntrezGene:6622  g556211_3p_x_at  g556213_3p_a_at  g6806896_3p_a_at
 GE57593  H6UYS0  H6UYS5  H6UYS7  HGNC:11138
 HPA005459  Hs.21374  Hs.21374.0.A1_3p_at  Hs.76930.1.A1_3p_a_at  ILMN_1701933
 ILMN_1766165  IPR001058  IPR002460  JN709859  JN709861
 JN709862  JN709864  JN709865  JN709867  JN709868
 L08850  L36674  L36675  MIM:163890  NM_000345
 NM_001146054  NM_001146055  NM_007308  NP_000336  NP_001139526
 NP_001139527  NP_009292  OTTHUMP00000161559  OTTHUMP00000161560  OTTHUMP00000161561
 OTTHUMP00000218549  OTTHUMP00000218550  OTTHUMP00000218551  OTTHUMP00000218553  PF01387
 PH_hs_0004441  PR01211  PR01212  R-HSA-392499  R-HSA-977225
 SNCA  SNCA-001  SNCA-002  SNCA-003  SNCA-004
 SNCA-005  SNCA-006  SNCA-008  SNCA-201  SNCA-202
 SNCA-203  U46897  U46898  U46899  U46901
 U46901_at  uc003hso.3  uc003hsp.4  uc003hsq.4  uc003hsr.4
 uc010ikt.4  uc031sgg.2  uc062yev.1  uc062yew.1  uc062yex.1
 uc062yey.1  UPI000002B492  UPI000002B493  UPI000003173B  XM_011532208
 XP_011530510
Secondary Identifiers SYUA_HUMAN, A8K2A4, Q13701, Q4JHI3, Q6IAU6
Gene Names SNCA, NACP, PARK1
Chain chain:1-140
This entry is a component of:
repeatedUnit
hasMember
Reference Genes
Database Identifier
dbSNP Gene 6622
CTD Gene 6622
BioGPS Gene 6622
NCBI Gene 6622
ENSEMBL ENSG00000145335
KEGG Gene SNCA
Orphanet 15532
Reference Transcripts
Database Identifier
RefSeq NM_001146055
Cross References
Database Identifier
RefSeq NP_001139527, NP_001139526, NP_000336, NP_009292
DOCK Blaster 4RIL, 4ZNN, 5CRW, 4R0W, 4RIK, 3Q29, 4BXL, 4R0U, 3Q25, 3Q26, 3Q27, 3Q28, 2JN5, 2KKW, 2X6M, 1XQ8, 2M55
HMDB_protein HMDBP02388
PRO P37840
GeneCards P37840
UCSC human P37840
Protein Data Bank 4RIL, 4ZNN, 5CRW, 4R0W, 4RIK, 3Q29, 4BXL, 4R0U, 3Q25, 3Q26, 3Q27, 3Q28, 2JN5, 2KKW, 2X6M, 1XQ8, 2M55
Interactions
Confidence Score Interactor Accession Interactor Name Evidence
0.982 P37840 SYUA_HUMAN 32
0.825 Q9Y6H5 SNCAP_HUMAN 22
0.74 P08107 HSP71_HUMAN 7
0.626 Q9UI14 PRAF1_HUMAN 4
0.582 CHEBI:17552 GDP 5
0.576 Q01959 SC6A3_HUMAN 3
0.558 P00519-1 ABL1 6
0.556 Q5S007 LRRK2_HUMAN 6
0.556 Q61327 SC6A3_MOUSE 5
0.544 P10636-8 MAPT 3
0.544 P49841 GSK3B_HUMAN 2
0.543 P42858 HD_HUMAN 4
0.527 Q9WV55 VAPA_MOUSE 2
0.512 O88507 CNTFR_MOUSE 3
0.508 P00414 COX3_HUMAN 3
0.499 P17600 SYN1_HUMAN 2
0.463 P00519-2 ABL1 5
0.462 Q08406 CNTFR_RAT 3