Reactome: A Curated Pathway Database

C4b binding protein binds Protein S (R-HSA-981665)

Species Homo sapiens


The beta subunit of C4b binding protein binds and inactivates Protein S, a vitamin K dependent anticoagulation factor. This may represent part of a mechanism for fine-tuning the process of phagocytosis (Kask et al. 2004).

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Additional Information
Compartment plasma membrane , extracellular region
Literature References
pubMedId Title Journal Year
6454142 High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein Proc Natl Acad Sci U S A 1981