Reactome: A Curated Pathway Database

Ion channel transport

Stable Identifier
Homo sapiens
Locations in the PathwayBrowser

Ion channels mediate the flow of ions across the plasma membrane of cells. They are integral membrane proteins, typically a multimer of proteins, which, when arranged in the membrane, create a pore for the flow of ions. There are different types of ion channels. P-type ATPases undergo conformational changes to translocate ions. Ligand-gated ion channels operate like a gate, opened or closed by a chemical signal. Voltage-gated ion channels are activated by changes in electrical potential difference at the membrane (Purves, 2001; Kuhlbrandt, 2004).

Literature References
PubMed ID Title Journal Year
15071553 Biology, structure and mechanism of P-type ATPases Nat Rev Mol Cell Biol 2004
  Neuroscience (2nd ed.)   2001
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Orthologous Events