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Table of Contents
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Citing us
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GSH [extracellular region]
Stable Identifier
R-ALL-1247892
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
Reduced glutathione, glutathione, 5-L-Glutamyl-L-cysteinylglycine, N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine, gamma-L-Glutamyl-L-cysteinyl-glycine
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to external stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to chemical stress (Bos taurus)
Detoxification of Reactive Oxygen Species (Bos taurus)
GPX5,6 reduce H2O2 to H2O (Bos taurus)
GSH [extracellular region]
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase II - Conjugation of compounds (Bos taurus)
Glutathione conjugation (Bos taurus)
Glutathione synthesis and recycling (Bos taurus)
GGT dimers hydrolyse GSH (Bos taurus)
GSH [extracellular region]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase II - Conjugation of compounds (Caenorhabditis elegans)
Glutathione conjugation (Caenorhabditis elegans)
Glutathione synthesis and recycling (Caenorhabditis elegans)
GGT dimers hydrolyse GSH (Caenorhabditis elegans)
GSH [extracellular region]
Cellular responses to external stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
Detoxification of Reactive Oxygen Species (Canis familiaris)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
GSH [extracellular region]
GPX5,6 reduce H2O2 to H2O (Canis familiaris)
GSH [extracellular region]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase II - Conjugation of compounds (Canis familiaris)
Glutathione conjugation (Canis familiaris)
Glutathione synthesis and recycling (Canis familiaris)
GGT dimers hydrolyse GSH (Canis familiaris)
GSH [extracellular region]
Cellular responses to external stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
Detoxification of Reactive Oxygen Species (Danio rerio)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Danio rerio)
GSH [extracellular region]
GPX5,6 reduce H2O2 to H2O (Danio rerio)
GSH [extracellular region]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase II - Conjugation of compounds (Danio rerio)
Glutathione conjugation (Danio rerio)
Glutathione synthesis and recycling (Danio rerio)
GGT dimers hydrolyse GSH (Danio rerio)
GSH [extracellular region]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase II - Conjugation of compounds (Drosophila melanogaster)
Glutathione conjugation (Drosophila melanogaster)
Glutathione synthesis and recycling (Drosophila melanogaster)
GGT dimers hydrolyse GSH (Drosophila melanogaster)
GSH [extracellular region]
Cellular responses to external stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
Detoxification of Reactive Oxygen Species (Gallus gallus)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Gallus gallus)
GSH [extracellular region]
GPX5,6 reduce H2O2 to H2O (Gallus gallus)
GSH [extracellular region]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase II - Conjugation of compounds (Gallus gallus)
Glutathione conjugation (Gallus gallus)
Glutathione synthesis and recycling (Gallus gallus)
GGT dimers hydrolyse GSH (Gallus gallus)
GSH [extracellular region]
Cellular responses to external stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Detoxification of Reactive Oxygen Species (Homo sapiens)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
GSH [extracellular region]
GPX5,6 reduce H2O2 to H2O (Homo sapiens)
GSH [extracellular region]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Metabolic disorders of biological oxidation enzymes (Homo sapiens)
Defective GGT1 causes GLUTH (Homo sapiens)
Defective GGT1 does not hydrolyse GSH (Homo sapiens)
GSH [extracellular region]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Glutathione conjugation (Homo sapiens)
Glutathione synthesis and recycling (Homo sapiens)
GGT dimers hydrolyse GSH (Homo sapiens)
GSH [extracellular region]
GSH translocates from cytosol to extracellular region (Homo sapiens)
GSH [extracellular region]
Cellular responses to external stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
Detoxification of Reactive Oxygen Species (Mus musculus)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
GSH [extracellular region]
GPX5,6 reduce H2O2 to H2O (Mus musculus)
GSH [extracellular region]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase II - Conjugation of compounds (Mus musculus)
Glutathione conjugation (Mus musculus)
Glutathione synthesis and recycling (Mus musculus)
GGT dimers hydrolyse GSH (Mus musculus)
GSH [extracellular region]
Cellular responses to external stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
Detoxification of Reactive Oxygen Species (Rattus norvegicus)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
GSH [extracellular region]
GPX5,6 reduce H2O2 to H2O (Rattus norvegicus)
GSH [extracellular region]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase II - Conjugation of compounds (Rattus norvegicus)
Glutathione conjugation (Rattus norvegicus)
Glutathione synthesis and recycling (Rattus norvegicus)
GGT dimers hydrolyse GSH (Rattus norvegicus)
GSH [extracellular region]
Metabolism (Saccharomyces cerevisiae)
Biological oxidations (Saccharomyces cerevisiae)
Phase II - Conjugation of compounds (Saccharomyces cerevisiae)
Glutathione conjugation (Saccharomyces cerevisiae)
Glutathione synthesis and recycling (Saccharomyces cerevisiae)
GGT dimers hydrolyse GSH (Saccharomyces cerevisiae)
GSH [extracellular region]
Metabolism (Schizosaccharomyces pombe)
Biological oxidations (Schizosaccharomyces pombe)
Phase II - Conjugation of compounds (Schizosaccharomyces pombe)
Glutathione conjugation (Schizosaccharomyces pombe)
Glutathione synthesis and recycling (Schizosaccharomyces pombe)
GGT dimers hydrolyse GSH (Schizosaccharomyces pombe)
GSH [extracellular region]
Cellular responses to external stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to chemical stress (Sus scrofa)
Detoxification of Reactive Oxygen Species (Sus scrofa)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
GSH [extracellular region]
GPX5,6 reduce H2O2 to H2O (Sus scrofa)
GSH [extracellular region]
Cellular responses to external stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to chemical stress (Xenopus tropicalis)
Detoxification of Reactive Oxygen Species (Xenopus tropicalis)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Xenopus tropicalis)
GSH [extracellular region]
GPX5,6 reduce H2O2 to H2O (Xenopus tropicalis)
GSH [extracellular region]
External Reference Information
External Reference
glutathione [ChEBI:16856]
Participates
as an input of
Defective GGT1 does not hydrolyse GSH (Homo sapiens)
GGT dimers hydrolyse GSH (Bos taurus)
GGT dimers hydrolyse GSH (Caenorhabditis elegans)
GGT dimers hydrolyse GSH (Canis familiaris)
GGT dimers hydrolyse GSH (Drosophila melanogaster)
GGT dimers hydrolyse GSH (Danio rerio)
GGT dimers hydrolyse GSH (Gallus gallus)
GGT dimers hydrolyse GSH (Homo sapiens)
GGT dimers hydrolyse GSH (Mus musculus)
GGT dimers hydrolyse GSH (Rattus norvegicus)
GGT dimers hydrolyse GSH (Saccharomyces cerevisiae)
GGT dimers hydrolyse GSH (Schizosaccharomyces pombe)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Danio rerio)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Gallus gallus)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Xenopus tropicalis)
GPX5,6 reduce H2O2 to H2O (Bos taurus)
GPX5,6 reduce H2O2 to H2O (Canis familiaris)
GPX5,6 reduce H2O2 to H2O (Danio rerio)
GPX5,6 reduce H2O2 to H2O (Gallus gallus)
GPX5,6 reduce H2O2 to H2O (Homo sapiens)
GPX5,6 reduce H2O2 to H2O (Mus musculus)
GPX5,6 reduce H2O2 to H2O (Rattus norvegicus)
GPX5,6 reduce H2O2 to H2O (Sus scrofa)
GPX5,6 reduce H2O2 to H2O (Xenopus tropicalis)
as an output of
GSH translocates from cytosol to extracellular region (Homo sapiens)
Other forms of this molecule
GSH [endoplasmic reticulum membrane]
GSH [endoplasmic reticulum lumen]
GSH [mitochondrial matrix]
GSH [periplasmic space]
GSH [cytosol]
Cross References
COMPOUND
C00051
PubChem Substance
11533291
HMDB Metabolite
HMDB0000125
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