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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
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How do I search ?
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Analysis Gene Expression
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ARA [endoplasmic reticulum lumen]
Stable Identifier
R-ALL-140356
Type
Chemical Compound [SimpleEntity]
Compartment
endoplasmic reticulum lumen
Synonyms
arachidonic acid
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
COX reactions (Bos taurus)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Bos taurus)
ARA [endoplasmic reticulum lumen]
Cytochrome P450 - arranged by substrate type (Bos taurus)
Fatty acids (Bos taurus)
CYP2J2 oxidises ARA (Bos taurus)
ARA [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Bos taurus)
ARA [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Bos taurus)
ARA [endoplasmic reticulum lumen]
Metabolism of lipids (Bos taurus)
Fatty acid metabolism (Bos taurus)
Arachidonic acid metabolism (Bos taurus)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Bos taurus)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Bos taurus)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Bos taurus)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Bos taurus)
ARA [endoplasmic reticulum lumen]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Bos taurus)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Bos taurus)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is oxidised to PGG2 by PTGS2 (Bos taurus)
ARA [endoplasmic reticulum lumen]
Immune System (Caenorhabditis elegans)
Innate Immune System (Caenorhabditis elegans)
Fcgamma receptor (FCGR) dependent phagocytosis (Caenorhabditis elegans)
Role of phospholipids in phagocytosis (Caenorhabditis elegans)
Production of AA by iPLA2 upon FCGR activation (Caenorhabditis elegans)
ARA [endoplasmic reticulum lumen]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase I - Functionalization of compounds (Caenorhabditis elegans)
Cytochrome P450 - arranged by substrate type (Caenorhabditis elegans)
Fatty acids (Caenorhabditis elegans)
CYP2J2 oxidises ARA (Caenorhabditis elegans)
ARA [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Caenorhabditis elegans)
ARA [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Caenorhabditis elegans)
ARA [endoplasmic reticulum lumen]
Miscellaneous substrates (Caenorhabditis elegans)
CYP2U1 19-hydroxylates ARA (Caenorhabditis elegans)
ARA [endoplasmic reticulum lumen]
Metabolism of lipids (Caenorhabditis elegans)
Fatty acid metabolism (Caenorhabditis elegans)
Arachidonic acid metabolism (Caenorhabditis elegans)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Caenorhabditis elegans)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Caenorhabditis elegans)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Caenorhabditis elegans)
ARA [endoplasmic reticulum lumen]
Immune System (Canis familiaris)
Innate Immune System (Canis familiaris)
Fcgamma receptor (FCGR) dependent phagocytosis (Canis familiaris)
Role of phospholipids in phagocytosis (Canis familiaris)
Production of AA by iPLA2 upon FCGR activation (Canis familiaris)
ARA [endoplasmic reticulum lumen]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
COX reactions (Canis familiaris)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Canis familiaris)
ARA [endoplasmic reticulum lumen]
Cytochrome P450 - arranged by substrate type (Canis familiaris)
Fatty acids (Canis familiaris)
CYP2J2 oxidises ARA (Canis familiaris)
ARA [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Canis familiaris)
ARA [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Canis familiaris)
ARA [endoplasmic reticulum lumen]
Miscellaneous substrates (Canis familiaris)
CYP2U1 19-hydroxylates ARA (Canis familiaris)
ARA [endoplasmic reticulum lumen]
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Arachidonic acid metabolism (Canis familiaris)
Hydrolysis of phosphatidylcholine (Canis familiaris)
ARA [endoplasmic reticulum lumen]
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Canis familiaris)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Canis familiaris)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Canis familiaris)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Canis familiaris)
ARA [endoplasmic reticulum lumen]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Canis familiaris)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Canis familiaris)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is oxidised to PGG2 by PTGS2 (Canis familiaris)
ARA [endoplasmic reticulum lumen]
Signal Transduction (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (i) signalling events (Canis familiaris)
Opioid Signalling (Canis familiaris)
G-protein mediated events (Canis familiaris)
PLC beta mediated events (Canis familiaris)
Ca-dependent events (Canis familiaris)
phospho-PLA2 pathway (Canis familiaris)
Hydrolysis of phosphatidylcholine (Canis familiaris)
ARA [endoplasmic reticulum lumen]
Immune System (Danio rerio)
Innate Immune System (Danio rerio)
Fcgamma receptor (FCGR) dependent phagocytosis (Danio rerio)
Role of phospholipids in phagocytosis (Danio rerio)
Production of AA by iPLA2 upon FCGR activation (Danio rerio)
ARA [endoplasmic reticulum lumen]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
COX reactions (Danio rerio)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Danio rerio)
ARA [endoplasmic reticulum lumen]
Cytochrome P450 - arranged by substrate type (Danio rerio)
Fatty acids (Danio rerio)
CYP2J2 oxidises ARA (Danio rerio)
ARA [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Danio rerio)
ARA [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Danio rerio)
ARA [endoplasmic reticulum lumen]
Miscellaneous substrates (Danio rerio)
CYP2U1 19-hydroxylates ARA (Danio rerio)
ARA [endoplasmic reticulum lumen]
Metabolism of lipids (Danio rerio)
Fatty acid metabolism (Danio rerio)
Arachidonic acid metabolism (Danio rerio)
Hydrolysis of phosphatidylcholine (Danio rerio)
ARA [endoplasmic reticulum lumen]
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Danio rerio)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Danio rerio)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Danio rerio)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Danio rerio)
ARA [endoplasmic reticulum lumen]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Danio rerio)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Danio rerio)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is oxidised to PGG2 by PTGS2 (Danio rerio)
ARA [endoplasmic reticulum lumen]
Signal Transduction (Danio rerio)
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (i) signalling events (Danio rerio)
Opioid Signalling (Danio rerio)
G-protein mediated events (Danio rerio)
PLC beta mediated events (Danio rerio)
Ca-dependent events (Danio rerio)
phospho-PLA2 pathway (Danio rerio)
Hydrolysis of phosphatidylcholine (Danio rerio)
ARA [endoplasmic reticulum lumen]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Phase I - Functionalization of compounds (Dictyostelium discoideum)
Cytochrome P450 - arranged by substrate type (Dictyostelium discoideum)
Fatty acids (Dictyostelium discoideum)
CYP2J2 oxidises ARA (Dictyostelium discoideum)
ARA [endoplasmic reticulum lumen]
Miscellaneous substrates (Dictyostelium discoideum)
CYP2U1 19-hydroxylates ARA (Dictyostelium discoideum)
ARA [endoplasmic reticulum lumen]
Metabolism of lipids (Dictyostelium discoideum)
Fatty acid metabolism (Dictyostelium discoideum)
Arachidonic acid metabolism (Dictyostelium discoideum)
Hydrolysis of phosphatidylcholine (Dictyostelium discoideum)
ARA [endoplasmic reticulum lumen]
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Dictyostelium discoideum)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Dictyostelium discoideum)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Dictyostelium discoideum)
ARA [endoplasmic reticulum lumen]
Signal Transduction (Dictyostelium discoideum)
Signaling by GPCR (Dictyostelium discoideum)
GPCR downstream signalling (Dictyostelium discoideum)
G alpha (i) signalling events (Dictyostelium discoideum)
Opioid Signalling (Dictyostelium discoideum)
G-protein mediated events (Dictyostelium discoideum)
PLC beta mediated events (Dictyostelium discoideum)
Ca-dependent events (Dictyostelium discoideum)
phospho-PLA2 pathway (Dictyostelium discoideum)
Hydrolysis of phosphatidylcholine (Dictyostelium discoideum)
ARA [endoplasmic reticulum lumen]
Immune System (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Fcgamma receptor (FCGR) dependent phagocytosis (Drosophila melanogaster)
Role of phospholipids in phagocytosis (Drosophila melanogaster)
Production of AA by iPLA2 upon FCGR activation (Drosophila melanogaster)
ARA [endoplasmic reticulum lumen]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase I - Functionalization of compounds (Drosophila melanogaster)
Cytochrome P450 - arranged by substrate type (Drosophila melanogaster)
Fatty acids (Drosophila melanogaster)
CYP4B1 12-hydroxylates ARA (Drosophila melanogaster)
ARA [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Drosophila melanogaster)
ARA [endoplasmic reticulum lumen]
Miscellaneous substrates (Drosophila melanogaster)
CYP2U1 19-hydroxylates ARA (Drosophila melanogaster)
ARA [endoplasmic reticulum lumen]
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Arachidonic acid metabolism (Drosophila melanogaster)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Drosophila melanogaster)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Drosophila melanogaster)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Drosophila melanogaster)
ARA [endoplasmic reticulum lumen]
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
Fcgamma receptor (FCGR) dependent phagocytosis (Gallus gallus)
Role of phospholipids in phagocytosis (Gallus gallus)
Production of AA by iPLA2 upon FCGR activation (Gallus gallus)
ARA [endoplasmic reticulum lumen]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
COX reactions (Gallus gallus)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Gallus gallus)
ARA [endoplasmic reticulum lumen]
Cytochrome P450 - arranged by substrate type (Gallus gallus)
Fatty acids (Gallus gallus)
CYP2J2 oxidises ARA (Gallus gallus)
ARA [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Gallus gallus)
ARA [endoplasmic reticulum lumen]
Miscellaneous substrates (Gallus gallus)
CYP2U1 19-hydroxylates ARA (Gallus gallus)
ARA [endoplasmic reticulum lumen]
Metabolism of lipids (Gallus gallus)
Fatty acid metabolism (Gallus gallus)
Arachidonic acid metabolism (Gallus gallus)
Hydrolysis of phosphatidylcholine (Gallus gallus)
ARA [endoplasmic reticulum lumen]
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Gallus gallus)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Gallus gallus)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Gallus gallus)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Gallus gallus)
ARA [endoplasmic reticulum lumen]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Gallus gallus)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Gallus gallus)
ARA [endoplasmic reticulum lumen]
Signal Transduction (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (i) signalling events (Gallus gallus)
Opioid Signalling (Gallus gallus)
G-protein mediated events (Gallus gallus)
PLC beta mediated events (Gallus gallus)
Ca-dependent events (Gallus gallus)
phospho-PLA2 pathway (Gallus gallus)
Hydrolysis of phosphatidylcholine (Gallus gallus)
ARA [endoplasmic reticulum lumen]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Metabolic disorders of biological oxidation enzymes (Homo sapiens)
Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56) (Homo sapiens)
Defective CYP2U1 does not omega-hydroxylate ARA (Homo sapiens)
ARA [endoplasmic reticulum lumen]
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Role of phospholipids in phagocytosis (Homo sapiens)
Production of AA by iPLA2 upon FCGR activation (Homo sapiens)
ARA [endoplasmic reticulum lumen]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
COX reactions (Homo sapiens)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Homo sapiens)
ARA [endoplasmic reticulum lumen]
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Fatty acids (Homo sapiens)
CYP2J2 oxidises ARA (Homo sapiens)
ARA [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Homo sapiens)
ARA [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Homo sapiens)
ARA [endoplasmic reticulum lumen]
Miscellaneous substrates (Homo sapiens)
CYP2U1 19-hydroxylates ARA (Homo sapiens)
ARA [endoplasmic reticulum lumen]
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Arachidonic acid metabolism (Homo sapiens)
Arachidonate diffuses across the ER membrane (Homo sapiens)
ARA [endoplasmic reticulum lumen]
Hydrolysis of phosphatidylcholine (Homo sapiens)
ARA [endoplasmic reticulum lumen]
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Homo sapiens)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Homo sapiens)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Homo sapiens)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Homo sapiens)
ARA [endoplasmic reticulum lumen]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Homo sapiens)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Homo sapiens)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is oxidised to PGG2 by PTGS2 (Homo sapiens)
ARA [endoplasmic reticulum lumen]
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Opioid Signalling (Homo sapiens)
G-protein mediated events (Homo sapiens)
PLC beta mediated events (Homo sapiens)
Ca-dependent events (Homo sapiens)
phospho-PLA2 pathway (Homo sapiens)
Hydrolysis of phosphatidylcholine (Homo sapiens)
ARA [endoplasmic reticulum lumen]
Immune System (Mus musculus)
Innate Immune System (Mus musculus)
Fcgamma receptor (FCGR) dependent phagocytosis (Mus musculus)
Role of phospholipids in phagocytosis (Mus musculus)
Production of AA by iPLA2 upon FCGR activation (Mus musculus)
ARA [endoplasmic reticulum lumen]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
COX reactions (Mus musculus)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Mus musculus)
ARA [endoplasmic reticulum lumen]
Cytochrome P450 - arranged by substrate type (Mus musculus)
Fatty acids (Mus musculus)
CYP2J2 oxidises ARA (Mus musculus)
ARA [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Mus musculus)
ARA [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Mus musculus)
ARA [endoplasmic reticulum lumen]
Miscellaneous substrates (Mus musculus)
CYP2U1 19-hydroxylates ARA (Mus musculus)
ARA [endoplasmic reticulum lumen]
Metabolism of lipids (Mus musculus)
Fatty acid metabolism (Mus musculus)
Arachidonic acid metabolism (Mus musculus)
Hydrolysis of phosphatidylcholine (Mus musculus)
ARA [endoplasmic reticulum lumen]
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Mus musculus)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Mus musculus)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Mus musculus)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Mus musculus)
ARA [endoplasmic reticulum lumen]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Mus musculus)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Mus musculus)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is oxidised to PGG2 by PTGS2 (Mus musculus)
ARA [endoplasmic reticulum lumen]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (i) signalling events (Mus musculus)
Opioid Signalling (Mus musculus)
G-protein mediated events (Mus musculus)
PLC beta mediated events (Mus musculus)
Ca-dependent events (Mus musculus)
phospho-PLA2 pathway (Mus musculus)
Hydrolysis of phosphatidylcholine (Mus musculus)
ARA [endoplasmic reticulum lumen]
Immune System (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Fcgamma receptor (FCGR) dependent phagocytosis (Rattus norvegicus)
Role of phospholipids in phagocytosis (Rattus norvegicus)
Production of AA by iPLA2 upon FCGR activation (Rattus norvegicus)
ARA [endoplasmic reticulum lumen]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
COX reactions (Rattus norvegicus)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Rattus norvegicus)
ARA [endoplasmic reticulum lumen]
Cytochrome P450 - arranged by substrate type (Rattus norvegicus)
Fatty acids (Rattus norvegicus)
CYP2J2 oxidises ARA (Rattus norvegicus)
ARA [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Rattus norvegicus)
ARA [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Rattus norvegicus)
ARA [endoplasmic reticulum lumen]
Miscellaneous substrates (Rattus norvegicus)
CYP2U1 19-hydroxylates ARA (Rattus norvegicus)
ARA [endoplasmic reticulum lumen]
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Arachidonic acid metabolism (Rattus norvegicus)
Hydrolysis of phosphatidylcholine (Rattus norvegicus)
ARA [endoplasmic reticulum lumen]
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Rattus norvegicus)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Rattus norvegicus)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Rattus norvegicus)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Rattus norvegicus)
ARA [endoplasmic reticulum lumen]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Rattus norvegicus)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Rattus norvegicus)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is oxidised to PGG2 by PTGS2 (Rattus norvegicus)
ARA [endoplasmic reticulum lumen]
Signal Transduction (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (i) signalling events (Rattus norvegicus)
Opioid Signalling (Rattus norvegicus)
G-protein mediated events (Rattus norvegicus)
PLC beta mediated events (Rattus norvegicus)
Ca-dependent events (Rattus norvegicus)
phospho-PLA2 pathway (Rattus norvegicus)
Hydrolysis of phosphatidylcholine (Rattus norvegicus)
ARA [endoplasmic reticulum lumen]
Metabolism (Saccharomyces cerevisiae)
Metabolism of lipids (Saccharomyces cerevisiae)
Fatty acid metabolism (Saccharomyces cerevisiae)
Arachidonic acid metabolism (Saccharomyces cerevisiae)
Hydrolysis of phosphatidylcholine (Saccharomyces cerevisiae)
ARA [endoplasmic reticulum lumen]
Signal Transduction (Saccharomyces cerevisiae)
Signaling by GPCR (Saccharomyces cerevisiae)
GPCR downstream signalling (Saccharomyces cerevisiae)
G alpha (i) signalling events (Saccharomyces cerevisiae)
Opioid Signalling (Saccharomyces cerevisiae)
G-protein mediated events (Saccharomyces cerevisiae)
PLC beta mediated events (Saccharomyces cerevisiae)
Ca-dependent events (Saccharomyces cerevisiae)
phospho-PLA2 pathway (Saccharomyces cerevisiae)
Hydrolysis of phosphatidylcholine (Saccharomyces cerevisiae)
ARA [endoplasmic reticulum lumen]
Metabolism (Schizosaccharomyces pombe)
Metabolism of lipids (Schizosaccharomyces pombe)
Fatty acid metabolism (Schizosaccharomyces pombe)
Arachidonic acid metabolism (Schizosaccharomyces pombe)
Hydrolysis of phosphatidylcholine (Schizosaccharomyces pombe)
ARA [endoplasmic reticulum lumen]
Signal Transduction (Schizosaccharomyces pombe)
Signaling by GPCR (Schizosaccharomyces pombe)
GPCR downstream signalling (Schizosaccharomyces pombe)
G alpha (i) signalling events (Schizosaccharomyces pombe)
Opioid Signalling (Schizosaccharomyces pombe)
G-protein mediated events (Schizosaccharomyces pombe)
PLC beta mediated events (Schizosaccharomyces pombe)
Ca-dependent events (Schizosaccharomyces pombe)
phospho-PLA2 pathway (Schizosaccharomyces pombe)
Hydrolysis of phosphatidylcholine (Schizosaccharomyces pombe)
ARA [endoplasmic reticulum lumen]
Immune System (Sus scrofa)
Innate Immune System (Sus scrofa)
Fcgamma receptor (FCGR) dependent phagocytosis (Sus scrofa)
Role of phospholipids in phagocytosis (Sus scrofa)
Production of AA by iPLA2 upon FCGR activation (Sus scrofa)
ARA [endoplasmic reticulum lumen]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
COX reactions (Sus scrofa)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Sus scrofa)
ARA [endoplasmic reticulum lumen]
Cytochrome P450 - arranged by substrate type (Sus scrofa)
Fatty acids (Sus scrofa)
CYP2J2 oxidises ARA (Sus scrofa)
ARA [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Sus scrofa)
ARA [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Sus scrofa)
ARA [endoplasmic reticulum lumen]
Miscellaneous substrates (Sus scrofa)
CYP2U1 19-hydroxylates ARA (Sus scrofa)
ARA [endoplasmic reticulum lumen]
Metabolism of lipids (Sus scrofa)
Fatty acid metabolism (Sus scrofa)
Arachidonic acid metabolism (Sus scrofa)
Hydrolysis of phosphatidylcholine (Sus scrofa)
ARA [endoplasmic reticulum lumen]
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Sus scrofa)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Sus scrofa)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Sus scrofa)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Sus scrofa)
ARA [endoplasmic reticulum lumen]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Sus scrofa)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Sus scrofa)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is oxidised to PGG2 by PTGS2 (Sus scrofa)
ARA [endoplasmic reticulum lumen]
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (i) signalling events (Sus scrofa)
Opioid Signalling (Sus scrofa)
G-protein mediated events (Sus scrofa)
PLC beta mediated events (Sus scrofa)
Ca-dependent events (Sus scrofa)
phospho-PLA2 pathway (Sus scrofa)
Hydrolysis of phosphatidylcholine (Sus scrofa)
ARA [endoplasmic reticulum lumen]
Immune System (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
Fcgamma receptor (FCGR) dependent phagocytosis (Xenopus tropicalis)
Role of phospholipids in phagocytosis (Xenopus tropicalis)
Production of AA by iPLA2 upon FCGR activation (Xenopus tropicalis)
ARA [endoplasmic reticulum lumen]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase I - Functionalization of compounds (Xenopus tropicalis)
COX reactions (Xenopus tropicalis)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Xenopus tropicalis)
ARA [endoplasmic reticulum lumen]
Cytochrome P450 - arranged by substrate type (Xenopus tropicalis)
Fatty acids (Xenopus tropicalis)
CYP4B1 12-hydroxylates ARA (Xenopus tropicalis)
ARA [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Xenopus tropicalis)
ARA [endoplasmic reticulum lumen]
Miscellaneous substrates (Xenopus tropicalis)
CYP2U1 19-hydroxylates ARA (Xenopus tropicalis)
ARA [endoplasmic reticulum lumen]
Metabolism of lipids (Xenopus tropicalis)
Fatty acid metabolism (Xenopus tropicalis)
Arachidonic acid metabolism (Xenopus tropicalis)
Hydrolysis of phosphatidylcholine (Xenopus tropicalis)
ARA [endoplasmic reticulum lumen]
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Xenopus tropicalis)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Xenopus tropicalis)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Xenopus tropicalis)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Xenopus tropicalis)
ARA [endoplasmic reticulum lumen]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Xenopus tropicalis)
Arachidonic acid is oxidised to PGG2 by PTGS1 (Xenopus tropicalis)
ARA [endoplasmic reticulum lumen]
Arachidonic acid is oxidised to PGG2 by PTGS2 (Xenopus tropicalis)
ARA [endoplasmic reticulum lumen]
Signal Transduction (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (i) signalling events (Xenopus tropicalis)
Opioid Signalling (Xenopus tropicalis)
G-protein mediated events (Xenopus tropicalis)
PLC beta mediated events (Xenopus tropicalis)
Ca-dependent events (Xenopus tropicalis)
phospho-PLA2 pathway (Xenopus tropicalis)
Hydrolysis of phosphatidylcholine (Xenopus tropicalis)
ARA [endoplasmic reticulum lumen]
External Reference Information
External Reference
arachidonic acid [ChEBI:15843]
Participant Of
input
Arachidonate diffuses across the ER membrane
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
Arachidonic acid is oxidised to PGG2 by PTGS1
Arachidonic acid is oxidised to PGG2 by PTGS1
Arachidonic acid is oxidised to PGG2 by PTGS1
Arachidonic acid is oxidised to PGG2 by PTGS1
Arachidonic acid is oxidised to PGG2 by PTGS1
Arachidonic acid is oxidised to PGG2 by PTGS1
Arachidonic acid is oxidised to PGG2 by PTGS1
Arachidonic acid is oxidised to PGG2 by PTGS1
Arachidonic acid is oxidised to PGG2 by PTGS1
Arachidonic acid is oxidised to PGG2 by PTGS2
Arachidonic acid is oxidised to PGG2 by PTGS2
Arachidonic acid is oxidised to PGG2 by PTGS2
Arachidonic acid is oxidised to PGG2 by PTGS2
Arachidonic acid is oxidised to PGG2 by PTGS2
Arachidonic acid is oxidised to PGG2 by PTGS2
Arachidonic acid is oxidised to PGG2 by PTGS2
Arachidonic acid is oxidised to PGG2 by PTGS2
CYP2J2 oxidises ARA
CYP2J2 oxidises ARA
CYP2J2 oxidises ARA
CYP2J2 oxidises ARA
CYP2J2 oxidises ARA
CYP2J2 oxidises ARA
CYP2J2 oxidises ARA
CYP2J2 oxidises ARA
CYP2J2 oxidises ARA
CYP2J2 oxidises ARA
CYP2U1 19-hydroxylates ARA
CYP2U1 19-hydroxylates ARA
CYP2U1 19-hydroxylates ARA
CYP2U1 19-hydroxylates ARA
CYP2U1 19-hydroxylates ARA
CYP2U1 19-hydroxylates ARA
CYP2U1 19-hydroxylates ARA
CYP2U1 19-hydroxylates ARA
CYP2U1 19-hydroxylates ARA
CYP2U1 19-hydroxylates ARA
CYP2U1 19-hydroxylates ARA
CYP4B1 12-hydroxylates ARA
CYP4B1 12-hydroxylates ARA
CYP4B1 12-hydroxylates ARA
CYP4B1 12-hydroxylates ARA
CYP4B1 12-hydroxylates ARA
CYP4B1 12-hydroxylates ARA
CYP4B1 12-hydroxylates ARA
CYP4B1 12-hydroxylates ARA
CYP4B1 12-hydroxylates ARA
CYP4B1 12-hydroxylates ARA
CYP4B1 12-hydroxylates ARA
CYP4F12 18-hydroxylates ARA
CYP4F12 18-hydroxylates ARA
CYP4F12 18-hydroxylates ARA
CYP4F12 18-hydroxylates ARA
CYP4F12 18-hydroxylates ARA
CYP4F12 18-hydroxylates ARA
CYP4F12 18-hydroxylates ARA
CYP4F12 18-hydroxylates ARA
CYP4F12 18-hydroxylates ARA
CYP4F12 18-hydroxylates ARA
Defective CYP2U1 does not omega-hydroxylate ARA
output
Hydrolysis of phosphatidylcholine
Hydrolysis of phosphatidylcholine
Hydrolysis of phosphatidylcholine
Hydrolysis of phosphatidylcholine
Hydrolysis of phosphatidylcholine
Hydrolysis of phosphatidylcholine
Hydrolysis of phosphatidylcholine
Hydrolysis of phosphatidylcholine
Hydrolysis of phosphatidylcholine
Hydrolysis of phosphatidylcholine
Hydrolysis of phosphatidylcholine
Production of AA by iPLA2 upon FCGR activation
Production of AA by iPLA2 upon FCGR activation
Production of AA by iPLA2 upon FCGR activation
Production of AA by iPLA2 upon FCGR activation
Production of AA by iPLA2 upon FCGR activation
Production of AA by iPLA2 upon FCGR activation
Production of AA by iPLA2 upon FCGR activation
Production of AA by iPLA2 upon FCGR activation
Production of AA by iPLA2 upon FCGR activation
Production of AA by iPLA2 upon FCGR activation
Other forms of this molecule
AA [lipid droplet]
AA [plasma membrane]
AA [lysosomal lumen]
AA [nucleoplasm]
AA [cytosol]
Cross References
COMPOUND
C00219
PubChem Substance
8145109
HMDB Metabolite
HMDB0001043
© 2021
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![ARA [endoplasmic reticulum lumen] icon](/icon/R-ICO-013819.svg){kind=icon}
