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HMBL [cytosol]
Stable Identifier
R-ALL-189449
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Hydroxymethylbilane, preuroporphyrinogen, preuroporphyrinogen(8-)
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of porphyrins (Bos taurus)
Heme biosynthesis (Bos taurus)
4 PBGs bind to form HMB (Bos taurus)
HMBL [cytosol]
UROS transforms HMB to URO3 (Bos taurus)
HMBL [cytosol]
Metabolism (Canis familiaris)
Metabolism of porphyrins (Canis familiaris)
Heme biosynthesis (Canis familiaris)
4 PBGs bind to form HMB (Canis familiaris)
HMBL [cytosol]
UROS transforms HMB to URO3 (Canis familiaris)
HMBL [cytosol]
Metabolism (Danio rerio)
Metabolism of porphyrins (Danio rerio)
Heme biosynthesis (Danio rerio)
4 PBGs bind to form HMB (Danio rerio)
HMBL [cytosol]
UROS transforms HMB to URO3 (Danio rerio)
HMBL [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of porphyrins (Dictyostelium discoideum)
Heme biosynthesis (Dictyostelium discoideum)
UROS transforms HMB to URO3 (Dictyostelium discoideum)
HMBL [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of porphyrins (Drosophila melanogaster)
Heme biosynthesis (Drosophila melanogaster)
4 PBGs bind to form HMB (Drosophila melanogaster)
HMBL [cytosol]
UROS transforms HMB to URO3 (Drosophila melanogaster)
HMBL [cytosol]
Metabolism (Gallus gallus)
Metabolism of porphyrins (Gallus gallus)
Heme biosynthesis (Gallus gallus)
4 PBGs bind to form HMB (Gallus gallus)
HMBL [cytosol]
UROS transforms HMB to URO3 (Gallus gallus)
HMBL [cytosol]
Metabolism (Homo sapiens)
Metabolism of porphyrins (Homo sapiens)
Heme biosynthesis (Homo sapiens)
4 PBGs bind to form HMB (Homo sapiens)
HMBL [cytosol]
HMBL spontaneously transforms to URO1 (Homo sapiens)
HMBL [cytosol]
UROS transforms HMB to URO3 (Homo sapiens)
HMBL [cytosol]
Metabolism (Mus musculus)
Metabolism of porphyrins (Mus musculus)
Heme biosynthesis (Mus musculus)
4 PBGs bind to form HMB (Mus musculus)
HMBL [cytosol]
UROS transforms HMB to URO3 (Mus musculus)
HMBL [cytosol]
Metabolism (Plasmodium falciparum)
Metabolism of porphyrins (Plasmodium falciparum)
Heme biosynthesis (Plasmodium falciparum)
4 PBGs bind to form HMB (Plasmodium falciparum)
HMBL [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of porphyrins (Rattus norvegicus)
Heme biosynthesis (Rattus norvegicus)
4 PBGs bind to form HMB (Rattus norvegicus)
HMBL [cytosol]
UROS transforms HMB to URO3 (Rattus norvegicus)
HMBL [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of porphyrins (Saccharomyces cerevisiae)
Heme biosynthesis (Saccharomyces cerevisiae)
4 PBGs bind to form HMB (Saccharomyces cerevisiae)
HMBL [cytosol]
UROS transforms HMB to URO3 (Saccharomyces cerevisiae)
HMBL [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of porphyrins (Schizosaccharomyces pombe)
Heme biosynthesis (Schizosaccharomyces pombe)
4 PBGs bind to form HMB (Schizosaccharomyces pombe)
HMBL [cytosol]
UROS transforms HMB to URO3 (Schizosaccharomyces pombe)
HMBL [cytosol]
Metabolism (Sus scrofa)
Metabolism of porphyrins (Sus scrofa)
Heme biosynthesis (Sus scrofa)
4 PBGs bind to form HMB (Sus scrofa)
HMBL [cytosol]
UROS transforms HMB to URO3 (Sus scrofa)
HMBL [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of porphyrins (Xenopus tropicalis)
Heme biosynthesis (Xenopus tropicalis)
4 PBGs bind to form HMB (Xenopus tropicalis)
HMBL [cytosol]
UROS transforms HMB to URO3 (Xenopus tropicalis)
HMBL [cytosol]
External Reference Information
External Reference
preuroporphyrinogen(8-) [ChEBI:57845]
Participant Of
input
HMBL spontaneously transforms to URO1
hydroxymethylbilane => uroporphyrinogen I + H2O
hydroxymethylbilane => uroporphyrinogen III + H2O
UROS transforms HMB to URO3
UROS transforms HMB to URO3
UROS transforms HMB to URO3
UROS transforms HMB to URO3
UROS transforms HMB to URO3
UROS transforms HMB to URO3
UROS transforms HMB to URO3
UROS transforms HMB to URO3
UROS transforms HMB to URO3
UROS transforms HMB to URO3
UROS transforms HMB to URO3
UROS transforms HMB to URO3
UROS transforms HMB to URO3
output
4 PBGs bind to form HMB
4 PBGs bind to form HMB
4 PBGs bind to form HMB
4 PBGs bind to form HMB
4 PBGs bind to form HMB
4 PBGs bind to form HMB
4 PBGs bind to form HMB
4 PBGs bind to form HMB
4 PBGs bind to form HMB
4 PBGs bind to form HMB
4 PBGs bind to form HMB
4 PBGs bind to form HMB
4 PBGs bind to form HMB
4 porphobilinogen + H2O => hydroxymethylbilane + 4 NH3
Cross References
ZINC
000096014964
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