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4,4DMCHtOL [endoplasmic reticulum membrane]
Stable Identifier
R-ALL-194644
Type
Chemical Compound [SimpleEntity]
Compartment
endoplasmic reticulum membrane
Synonyms
4,4DMCHOLtrienol, 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol, 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Cytochrome P450 - arranged by substrate type (Bos taurus)
Endogenous sterols (Bos taurus)
CYP51A1 demethylates LNSOL (Bos taurus)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism of lipids (Bos taurus)
Metabolism of steroids (Bos taurus)
Cholesterol biosynthesis (Bos taurus)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Bos taurus)
4,4DMCHtOL [endoplasmic reticulum membrane]
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Bos taurus)
4,4DMCHtOL [endoplasmic reticulum membrane]
CYP51A1 demethylates LNSOL (Bos taurus)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Cytochrome P450 - arranged by substrate type (Canis familiaris)
Endogenous sterols (Canis familiaris)
CYP51A1 demethylates LNSOL (Canis familiaris)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism of lipids (Canis familiaris)
Metabolism of steroids (Canis familiaris)
Cholesterol biosynthesis (Canis familiaris)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Canis familiaris)
4,4DMCHtOL [endoplasmic reticulum membrane]
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Canis familiaris)
4,4DMCHtOL [endoplasmic reticulum membrane]
CYP51A1 demethylates LNSOL (Canis familiaris)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
Cytochrome P450 - arranged by substrate type (Danio rerio)
Endogenous sterols (Danio rerio)
CYP51A1 demethylates LNSOL (Danio rerio)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism of lipids (Danio rerio)
Metabolism of steroids (Danio rerio)
Cholesterol biosynthesis (Danio rerio)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Danio rerio)
4,4DMCHtOL [endoplasmic reticulum membrane]
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Danio rerio)
4,4DMCHtOL [endoplasmic reticulum membrane]
CYP51A1 demethylates LNSOL (Danio rerio)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Phase I - Functionalization of compounds (Dictyostelium discoideum)
Cytochrome P450 - arranged by substrate type (Dictyostelium discoideum)
Endogenous sterols (Dictyostelium discoideum)
CYP51A1 demethylates LNSOL (Dictyostelium discoideum)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism of lipids (Dictyostelium discoideum)
Metabolism of steroids (Dictyostelium discoideum)
Cholesterol biosynthesis (Dictyostelium discoideum)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Dictyostelium discoideum)
4,4DMCHtOL [endoplasmic reticulum membrane]
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Dictyostelium discoideum)
4,4DMCHtOL [endoplasmic reticulum membrane]
CYP51A1 demethylates LNSOL (Dictyostelium discoideum)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Metabolism of steroids (Drosophila melanogaster)
Cholesterol biosynthesis (Drosophila melanogaster)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Drosophila melanogaster)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
Cytochrome P450 - arranged by substrate type (Gallus gallus)
Endogenous sterols (Gallus gallus)
CYP51A1 demethylates LNSOL (Gallus gallus)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism of lipids (Gallus gallus)
Metabolism of steroids (Gallus gallus)
Cholesterol biosynthesis (Gallus gallus)
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Gallus gallus)
4,4DMCHtOL [endoplasmic reticulum membrane]
CYP51A1 demethylates LNSOL (Gallus gallus)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Endogenous sterols (Homo sapiens)
CYP51A1 demethylates LNSOL (Homo sapiens)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Cholesterol biosynthesis (Homo sapiens)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Homo sapiens)
4,4DMCHtOL [endoplasmic reticulum membrane]
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Homo sapiens)
4,4DMCHtOL [endoplasmic reticulum membrane]
CYP51A1 demethylates LNSOL (Homo sapiens)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Endogenous sterols (Mus musculus)
CYP51A1 demethylates LNSOL (Mus musculus)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism of lipids (Mus musculus)
Metabolism of steroids (Mus musculus)
Cholesterol biosynthesis (Mus musculus)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Mus musculus)
4,4DMCHtOL [endoplasmic reticulum membrane]
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Mus musculus)
4,4DMCHtOL [endoplasmic reticulum membrane]
CYP51A1 demethylates LNSOL (Mus musculus)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Cytochrome P450 - arranged by substrate type (Rattus norvegicus)
Endogenous sterols (Rattus norvegicus)
CYP51A1 demethylates LNSOL (Rattus norvegicus)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism of lipids (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Cholesterol biosynthesis (Rattus norvegicus)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Rattus norvegicus)
4,4DMCHtOL [endoplasmic reticulum membrane]
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Rattus norvegicus)
4,4DMCHtOL [endoplasmic reticulum membrane]
CYP51A1 demethylates LNSOL (Rattus norvegicus)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism (Saccharomyces cerevisiae)
Biological oxidations (Saccharomyces cerevisiae)
Phase I - Functionalization of compounds (Saccharomyces cerevisiae)
Cytochrome P450 - arranged by substrate type (Saccharomyces cerevisiae)
Endogenous sterols (Saccharomyces cerevisiae)
CYP51A1 demethylates LNSOL (Saccharomyces cerevisiae)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism of lipids (Saccharomyces cerevisiae)
Metabolism of steroids (Saccharomyces cerevisiae)
Cholesterol biosynthesis (Saccharomyces cerevisiae)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Saccharomyces cerevisiae)
4,4DMCHtOL [endoplasmic reticulum membrane]
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Saccharomyces cerevisiae)
4,4DMCHtOL [endoplasmic reticulum membrane]
CYP51A1 demethylates LNSOL (Saccharomyces cerevisiae)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism (Schizosaccharomyces pombe)
Biological oxidations (Schizosaccharomyces pombe)
Phase I - Functionalization of compounds (Schizosaccharomyces pombe)
Cytochrome P450 - arranged by substrate type (Schizosaccharomyces pombe)
Endogenous sterols (Schizosaccharomyces pombe)
CYP51A1 demethylates LNSOL (Schizosaccharomyces pombe)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism of lipids (Schizosaccharomyces pombe)
Metabolism of steroids (Schizosaccharomyces pombe)
Cholesterol biosynthesis (Schizosaccharomyces pombe)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Schizosaccharomyces pombe)
4,4DMCHtOL [endoplasmic reticulum membrane]
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Schizosaccharomyces pombe)
4,4DMCHtOL [endoplasmic reticulum membrane]
CYP51A1 demethylates LNSOL (Schizosaccharomyces pombe)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Cytochrome P450 - arranged by substrate type (Sus scrofa)
Endogenous sterols (Sus scrofa)
CYP51A1 demethylates LNSOL (Sus scrofa)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism of lipids (Sus scrofa)
Metabolism of steroids (Sus scrofa)
Cholesterol biosynthesis (Sus scrofa)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Sus scrofa)
4,4DMCHtOL [endoplasmic reticulum membrane]
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Sus scrofa)
4,4DMCHtOL [endoplasmic reticulum membrane]
CYP51A1 demethylates LNSOL (Sus scrofa)
4,4DMCHtOL [endoplasmic reticulum membrane]
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Metabolism of steroids (Xenopus tropicalis)
Cholesterol biosynthesis (Xenopus tropicalis)
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Xenopus tropicalis)
4,4DMCHtOL [endoplasmic reticulum membrane]
External Reference Information
External Reference
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol [ChEBI:17813]
Participates
as an input of
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Saccharomyces cerevisiae)
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Schizosaccharomyces pombe)
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Dictyostelium discoideum)
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Gallus gallus)
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Xenopus tropicalis)
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Danio rerio)
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Sus scrofa)
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Bos taurus)
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Canis familiaris)
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Rattus norvegicus)
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Mus musculus)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Saccharomyces cerevisiae)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Schizosaccharomyces pombe)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Dictyostelium discoideum)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Drosophila melanogaster)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Danio rerio)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Sus scrofa)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Bos taurus)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Canis familiaris)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Rattus norvegicus)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Mus musculus)
4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Homo sapiens)
4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol (Homo sapiens)
as an output of
CYP51A1 demethylates LNSOL (Saccharomyces cerevisiae)
CYP51A1 demethylates LNSOL (Schizosaccharomyces pombe)
CYP51A1 demethylates LNSOL (Dictyostelium discoideum)
CYP51A1 demethylates LNSOL (Gallus gallus)
CYP51A1 demethylates LNSOL (Danio rerio)
CYP51A1 demethylates LNSOL (Sus scrofa)
CYP51A1 demethylates LNSOL (Bos taurus)
CYP51A1 demethylates LNSOL (Canis familiaris)
CYP51A1 demethylates LNSOL (Rattus norvegicus)
CYP51A1 demethylates LNSOL (Mus musculus)
CYP51A1 demethylates LNSOL (Homo sapiens)
Other forms of this molecule
4,4DMCHtOL [nuclear envelope]
Cross References
COMPOUND
C11455
HMDB Metabolite
HMDB0010315
,
HMDB0001023
ZINC
000003824121
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