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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
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Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
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Overlays
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NO [cytosol]
Stable Identifier
R-ALL-202124
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
nitric oxide
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Hemostasis (Bos taurus)
Platelet homeostasis (Bos taurus)
Nitric oxide stimulates guanylate cyclase (Bos taurus)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Bos taurus)
NO [cytosol]
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
ROS and RNS production in phagocytes (Bos taurus)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Bos taurus)
NO [cytosol]
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Pyruvate metabolism (Bos taurus)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Bos taurus)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Bos taurus)
eNOS activation (Bos taurus)
CYGB dioxygenates NO (Bos taurus)
NO [cytosol]
eNOS synthesizes NO (Bos taurus)
NO [cytosol]
Muscle contraction (Bos taurus)
Smooth Muscle Contraction (Bos taurus)
Cinaciguat binds sGC:NO (Bos taurus)
Guanylate cyclase:NO [cytosol] (Bos taurus)
NO [cytosol]
NO:sGC:cinaciguat [cytosol] (Bos taurus)
Guanylate cyclase:NO [cytosol] (Bos taurus)
NO [cytosol]
sGC stimulators bind sGC:NO (Bos taurus)
Guanylate cyclase:NO [cytosol] (Bos taurus)
NO [cytosol]
NO:sGC:sGC stimulators [cytosol] (Bos taurus)
Guanylate cyclase:NO [cytosol] (Bos taurus)
NO [cytosol]
Signal Transduction (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Extra-nuclear estrogen signaling (Bos taurus)
eNOS synthesizes NO (Bos taurus)
NO [cytosol]
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
VEGFR2 mediated vascular permeability (Bos taurus)
eNOS synthesizes NO (Bos taurus)
NO [cytosol]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Pyruvate metabolism (Caenorhabditis elegans)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Caenorhabditis elegans)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Caenorhabditis elegans)
eNOS activation (Caenorhabditis elegans)
CYGB dioxygenates NO (Caenorhabditis elegans)
NO [cytosol]
eNOS synthesizes NO (Caenorhabditis elegans)
NO [cytosol]
Signal Transduction (Caenorhabditis elegans)
Signaling by Nuclear Receptors (Caenorhabditis elegans)
ESR-mediated signaling (Caenorhabditis elegans)
Extra-nuclear estrogen signaling (Caenorhabditis elegans)
eNOS synthesizes NO (Caenorhabditis elegans)
NO [cytosol]
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by VEGF (Caenorhabditis elegans)
VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)
VEGFR2 mediated vascular permeability (Caenorhabditis elegans)
eNOS synthesizes NO (Caenorhabditis elegans)
NO [cytosol]
Hemostasis (Canis familiaris)
Platelet homeostasis (Canis familiaris)
Nitric oxide stimulates guanylate cyclase (Canis familiaris)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Canis familiaris)
NO [cytosol]
Immune System (Canis familiaris)
Innate Immune System (Canis familiaris)
ROS and RNS production in phagocytes (Canis familiaris)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Canis familiaris)
NO [cytosol]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Pyruvate metabolism (Canis familiaris)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Canis familiaris)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Canis familiaris)
eNOS activation (Canis familiaris)
CYGB dioxygenates NO (Canis familiaris)
NO [cytosol]
Muscle contraction (Canis familiaris)
Smooth Muscle Contraction (Canis familiaris)
Cinaciguat binds sGC:NO (Canis familiaris)
Guanylate cyclase:NO [cytosol] (Canis familiaris)
NO [cytosol]
NO:sGC:cinaciguat [cytosol] (Canis familiaris)
Guanylate cyclase:NO [cytosol] (Canis familiaris)
NO [cytosol]
sGC stimulators bind sGC:NO (Canis familiaris)
Guanylate cyclase:NO [cytosol] (Canis familiaris)
NO [cytosol]
NO:sGC:sGC stimulators [cytosol] (Canis familiaris)
Guanylate cyclase:NO [cytosol] (Canis familiaris)
NO [cytosol]
Hemostasis (Danio rerio)
Platelet homeostasis (Danio rerio)
Nitric oxide stimulates guanylate cyclase (Danio rerio)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Danio rerio)
NO [cytosol]
Immune System (Danio rerio)
Innate Immune System (Danio rerio)
ROS and RNS production in phagocytes (Danio rerio)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Danio rerio)
NO [cytosol]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Pyruvate metabolism (Danio rerio)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Danio rerio)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Danio rerio)
eNOS activation (Danio rerio)
CYGB dioxygenates NO (Danio rerio)
NO [cytosol]
Muscle contraction (Danio rerio)
Smooth Muscle Contraction (Danio rerio)
Cinaciguat binds sGC:NO (Danio rerio)
Guanylate cyclase:NO [cytosol] (Danio rerio)
NO [cytosol]
NO:sGC:cinaciguat [cytosol] (Danio rerio)
Guanylate cyclase:NO [cytosol] (Danio rerio)
NO [cytosol]
sGC stimulators bind sGC:NO (Danio rerio)
Guanylate cyclase:NO [cytosol] (Danio rerio)
NO [cytosol]
NO:sGC:sGC stimulators [cytosol] (Danio rerio)
Guanylate cyclase:NO [cytosol] (Danio rerio)
NO [cytosol]
Hemostasis (Dictyostelium discoideum)
Platelet homeostasis (Dictyostelium discoideum)
Nitric oxide stimulates guanylate cyclase (Dictyostelium discoideum)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Dictyostelium discoideum)
NO [cytosol]
Immune System (Dictyostelium discoideum)
Innate Immune System (Dictyostelium discoideum)
ROS and RNS production in phagocytes (Dictyostelium discoideum)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Dictyostelium discoideum)
NO [cytosol]
Metabolism (Dictyostelium discoideum)
Aerobic respiration and respiratory electron transport (Dictyostelium discoideum)
Pyruvate metabolism (Dictyostelium discoideum)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Dictyostelium discoideum)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Dictyostelium discoideum)
eNOS activation (Dictyostelium discoideum)
eNOS synthesizes NO (Dictyostelium discoideum)
NO [cytosol]
Signal Transduction (Dictyostelium discoideum)
Signaling by Nuclear Receptors (Dictyostelium discoideum)
ESR-mediated signaling (Dictyostelium discoideum)
Extra-nuclear estrogen signaling (Dictyostelium discoideum)
eNOS synthesizes NO (Dictyostelium discoideum)
NO [cytosol]
Signaling by Receptor Tyrosine Kinases (Dictyostelium discoideum)
Signaling by VEGF (Dictyostelium discoideum)
VEGFA-VEGFR2 Pathway (Dictyostelium discoideum)
VEGFR2 mediated vascular permeability (Dictyostelium discoideum)
eNOS synthesizes NO (Dictyostelium discoideum)
NO [cytosol]
Hemostasis (Drosophila melanogaster)
Platelet homeostasis (Drosophila melanogaster)
Nitric oxide stimulates guanylate cyclase (Drosophila melanogaster)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Drosophila melanogaster)
NO [cytosol]
Immune System (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
ROS and RNS production in phagocytes (Drosophila melanogaster)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Drosophila melanogaster)
NO [cytosol]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism (Drosophila melanogaster)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Drosophila melanogaster)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Drosophila melanogaster)
eNOS activation (Drosophila melanogaster)
eNOS synthesizes NO (Drosophila melanogaster)
NO [cytosol]
Muscle contraction (Drosophila melanogaster)
Smooth Muscle Contraction (Drosophila melanogaster)
Cinaciguat binds sGC:NO (Drosophila melanogaster)
Guanylate cyclase:NO [cytosol] (Drosophila melanogaster)
NO [cytosol]
NO:sGC:cinaciguat [cytosol] (Drosophila melanogaster)
Guanylate cyclase:NO [cytosol] (Drosophila melanogaster)
NO [cytosol]
sGC stimulators bind sGC:NO (Drosophila melanogaster)
Guanylate cyclase:NO [cytosol] (Drosophila melanogaster)
NO [cytosol]
NO:sGC:sGC stimulators [cytosol] (Drosophila melanogaster)
Guanylate cyclase:NO [cytosol] (Drosophila melanogaster)
NO [cytosol]
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Extra-nuclear estrogen signaling (Drosophila melanogaster)
eNOS synthesizes NO (Drosophila melanogaster)
NO [cytosol]
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
eNOS synthesizes NO (Drosophila melanogaster)
NO [cytosol]
Hemostasis (Gallus gallus)
Platelet homeostasis (Gallus gallus)
Nitric oxide stimulates guanylate cyclase (Gallus gallus)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Gallus gallus)
NO [cytosol]
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
ROS and RNS production in phagocytes (Gallus gallus)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Gallus gallus)
NO [cytosol]
Metabolism (Gallus gallus)
Aerobic respiration and respiratory electron transport (Gallus gallus)
Pyruvate metabolism (Gallus gallus)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Gallus gallus)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Gallus gallus)
eNOS activation (Gallus gallus)
CYGB dioxygenates NO (Gallus gallus)
NO [cytosol]
eNOS synthesizes NO (Gallus gallus)
NO [cytosol]
Muscle contraction (Gallus gallus)
Smooth Muscle Contraction (Gallus gallus)
Cinaciguat binds sGC:NO (Gallus gallus)
Guanylate cyclase:NO [cytosol] (Gallus gallus)
NO [cytosol]
NO:sGC:cinaciguat [cytosol] (Gallus gallus)
Guanylate cyclase:NO [cytosol] (Gallus gallus)
NO [cytosol]
sGC stimulators bind sGC:NO (Gallus gallus)
Guanylate cyclase:NO [cytosol] (Gallus gallus)
NO [cytosol]
NO:sGC:sGC stimulators [cytosol] (Gallus gallus)
Guanylate cyclase:NO [cytosol] (Gallus gallus)
NO [cytosol]
Signal Transduction (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
ESR-mediated signaling (Gallus gallus)
Extra-nuclear estrogen signaling (Gallus gallus)
eNOS synthesizes NO (Gallus gallus)
NO [cytosol]
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
VEGFR2 mediated vascular permeability (Gallus gallus)
eNOS synthesizes NO (Gallus gallus)
NO [cytosol]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Cytoprotection by HMOX1 (Homo sapiens)
BIL scavenges NO (Homo sapiens)
NO [cytosol]
Detoxification of Reactive Oxygen Species (Homo sapiens)
Superoxide and nitric oxide react to peroxynitrite (Homo sapiens)
NO [cytosol]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Infection with Mycobacterium tuberculosis (Homo sapiens)
Latent infection - Other responses of Mtb to phagocytosis (Homo sapiens)
Tolerance by Mtb to nitric oxide produced by macrophages (Homo sapiens)
Nitrogen dioxide is reduced to NO by F420 (Homo sapiens)
NO [cytosol]
Hemostasis (Homo sapiens)
Platelet homeostasis (Homo sapiens)
Nitric oxide stimulates guanylate cyclase (Homo sapiens)
NO binds to Guanylate Cyclase (Homo sapiens)
NO [cytosol]
Guanylate cyclase:NO [cytosol] (Homo sapiens)
NO [cytosol]
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Homo sapiens)
NO [cytosol]
Soluble guanylate cyclase converts GTP to cGMP (Homo sapiens)
NO [cytosol]
Guanylate cyclase:NO [cytosol] (Homo sapiens)
NO [cytosol]
NO:sGC:cinaciguat [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
NO [cytosol]
NO:sGC:sGC stimulators [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
NO [cytosol]
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
ROS and RNS production in phagocytes (Homo sapiens)
NO and NO2 react to N2O3 (Homo sapiens)
NO [cytosol]
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Homo sapiens)
NO [cytosol]
Nitric oxide and O2 react to NO2 (Homo sapiens)
NO [cytosol]
Nitric oxide diffuses into the phagosome (Homo sapiens)
NO [cytosol]
Nitric oxide enters the bacterium (Homo sapiens)
NO [cytosol]
Nitric oxide oxidizes to nitrosyl ion (Homo sapiens)
NO [cytosol]
Superoxide and nitric oxide react to peroxynitrite (Homo sapiens)
NO [cytosol]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Pyruvate metabolism (Homo sapiens)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Homo sapiens)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Homo sapiens)
eNOS activation (Homo sapiens)
CYGB dioxygenates NO (Homo sapiens)
NO [cytosol]
Superoxide reacts rapidly with NO to form peroxynitrite (ONOO-) (Homo sapiens)
NO [cytosol]
eNOS synthesizes NO (Homo sapiens)
NO [cytosol]
Muscle contraction (Homo sapiens)
Smooth Muscle Contraction (Homo sapiens)
Cinaciguat binds sGC:NO (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
NO [cytosol]
NO:sGC:cinaciguat [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
NO [cytosol]
NO binds to Guanylate Cyclase (Homo sapiens)
NO [cytosol]
Guanylate cyclase:NO [cytosol] (Homo sapiens)
NO [cytosol]
Soluble guanylate cyclase converts GTP to cGMP (Homo sapiens)
NO [cytosol]
Guanylate cyclase:NO [cytosol] (Homo sapiens)
NO [cytosol]
NO:sGC:cinaciguat [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
NO [cytosol]
NO:sGC:sGC stimulators [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
NO [cytosol]
sGC stimulators bind sGC:NO (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
NO [cytosol]
NO:sGC:sGC stimulators [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
NO [cytosol]
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Extra-nuclear estrogen signaling (Homo sapiens)
eNOS synthesizes NO (Homo sapiens)
NO [cytosol]
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
VEGFR2 mediated vascular permeability (Homo sapiens)
eNOS synthesizes NO (Homo sapiens)
NO [cytosol]
Hemostasis (Mus musculus)
Platelet homeostasis (Mus musculus)
Nitric oxide stimulates guanylate cyclase (Mus musculus)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Mus musculus)
NO [cytosol]
Immune System (Mus musculus)
Innate Immune System (Mus musculus)
ROS and RNS production in phagocytes (Mus musculus)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Mus musculus)
NO [cytosol]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Pyruvate metabolism (Mus musculus)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Mus musculus)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Mus musculus)
eNOS activation (Mus musculus)
CYGB dioxygenates NO (Mus musculus)
NO [cytosol]
eNOS synthesizes NO (Mus musculus)
NO [cytosol]
Muscle contraction (Mus musculus)
Smooth Muscle Contraction (Mus musculus)
Cinaciguat binds sGC:NO (Mus musculus)
Guanylate cyclase:NO [cytosol] (Mus musculus)
NO [cytosol]
NO:sGC:cinaciguat [cytosol] (Mus musculus)
Guanylate cyclase:NO [cytosol] (Mus musculus)
NO [cytosol]
sGC stimulators bind sGC:NO (Mus musculus)
Guanylate cyclase:NO [cytosol] (Mus musculus)
NO [cytosol]
NO:sGC:sGC stimulators [cytosol] (Mus musculus)
Guanylate cyclase:NO [cytosol] (Mus musculus)
NO [cytosol]
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
ESR-mediated signaling (Mus musculus)
Extra-nuclear estrogen signaling (Mus musculus)
eNOS synthesizes NO (Mus musculus)
NO [cytosol]
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
VEGFR2 mediated vascular permeability (Mus musculus)
eNOS synthesizes NO (Mus musculus)
NO [cytosol]
Hemostasis (Plasmodium falciparum)
Platelet homeostasis (Plasmodium falciparum)
Nitric oxide stimulates guanylate cyclase (Plasmodium falciparum)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Plasmodium falciparum)
NO [cytosol]
Immune System (Plasmodium falciparum)
Innate Immune System (Plasmodium falciparum)
ROS and RNS production in phagocytes (Plasmodium falciparum)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Plasmodium falciparum)
NO [cytosol]
Metabolism (Plasmodium falciparum)
Aerobic respiration and respiratory electron transport (Plasmodium falciparum)
Pyruvate metabolism (Plasmodium falciparum)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Plasmodium falciparum)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Plasmodium falciparum)
eNOS activation (Plasmodium falciparum)
eNOS synthesizes NO (Plasmodium falciparum)
NO [cytosol]
Signal Transduction (Plasmodium falciparum)
Signaling by Nuclear Receptors (Plasmodium falciparum)
ESR-mediated signaling (Plasmodium falciparum)
Extra-nuclear estrogen signaling (Plasmodium falciparum)
eNOS synthesizes NO (Plasmodium falciparum)
NO [cytosol]
Signaling by Receptor Tyrosine Kinases (Plasmodium falciparum)
Signaling by VEGF (Plasmodium falciparum)
VEGFA-VEGFR2 Pathway (Plasmodium falciparum)
VEGFR2 mediated vascular permeability (Plasmodium falciparum)
eNOS synthesizes NO (Plasmodium falciparum)
NO [cytosol]
Hemostasis (Rattus norvegicus)
Platelet homeostasis (Rattus norvegicus)
Nitric oxide stimulates guanylate cyclase (Rattus norvegicus)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Rattus norvegicus)
NO [cytosol]
Immune System (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
ROS and RNS production in phagocytes (Rattus norvegicus)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Rattus norvegicus)
NO [cytosol]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Pyruvate metabolism (Rattus norvegicus)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Rattus norvegicus)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Rattus norvegicus)
eNOS activation (Rattus norvegicus)
CYGB dioxygenates NO (Rattus norvegicus)
NO [cytosol]
eNOS synthesizes NO (Rattus norvegicus)
NO [cytosol]
Muscle contraction (Rattus norvegicus)
Smooth Muscle Contraction (Rattus norvegicus)
Cinaciguat binds sGC:NO (Rattus norvegicus)
Guanylate cyclase:NO [cytosol] (Rattus norvegicus)
NO [cytosol]
NO:sGC:cinaciguat [cytosol] (Rattus norvegicus)
Guanylate cyclase:NO [cytosol] (Rattus norvegicus)
NO [cytosol]
sGC stimulators bind sGC:NO (Rattus norvegicus)
Guanylate cyclase:NO [cytosol] (Rattus norvegicus)
NO [cytosol]
NO:sGC:sGC stimulators [cytosol] (Rattus norvegicus)
Guanylate cyclase:NO [cytosol] (Rattus norvegicus)
NO [cytosol]
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
ESR-mediated signaling (Rattus norvegicus)
Extra-nuclear estrogen signaling (Rattus norvegicus)
eNOS synthesizes NO (Rattus norvegicus)
NO [cytosol]
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by VEGF (Rattus norvegicus)
VEGFA-VEGFR2 Pathway (Rattus norvegicus)
VEGFR2 mediated vascular permeability (Rattus norvegicus)
eNOS synthesizes NO (Rattus norvegicus)
NO [cytosol]
Hemostasis (Saccharomyces cerevisiae)
Platelet homeostasis (Saccharomyces cerevisiae)
Nitric oxide stimulates guanylate cyclase (Saccharomyces cerevisiae)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Saccharomyces cerevisiae)
NO [cytosol]
Immune System (Saccharomyces cerevisiae)
Innate Immune System (Saccharomyces cerevisiae)
ROS and RNS production in phagocytes (Saccharomyces cerevisiae)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Saccharomyces cerevisiae)
NO [cytosol]
Metabolism (Saccharomyces cerevisiae)
Aerobic respiration and respiratory electron transport (Saccharomyces cerevisiae)
Pyruvate metabolism (Saccharomyces cerevisiae)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Saccharomyces cerevisiae)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Saccharomyces cerevisiae)
eNOS activation (Saccharomyces cerevisiae)
eNOS synthesizes NO (Saccharomyces cerevisiae)
NO [cytosol]
Signal Transduction (Saccharomyces cerevisiae)
Signaling by Nuclear Receptors (Saccharomyces cerevisiae)
ESR-mediated signaling (Saccharomyces cerevisiae)
Extra-nuclear estrogen signaling (Saccharomyces cerevisiae)
eNOS synthesizes NO (Saccharomyces cerevisiae)
NO [cytosol]
Signaling by Receptor Tyrosine Kinases (Saccharomyces cerevisiae)
Signaling by VEGF (Saccharomyces cerevisiae)
VEGFA-VEGFR2 Pathway (Saccharomyces cerevisiae)
VEGFR2 mediated vascular permeability (Saccharomyces cerevisiae)
eNOS synthesizes NO (Saccharomyces cerevisiae)
NO [cytosol]
Hemostasis (Schizosaccharomyces pombe)
Platelet homeostasis (Schizosaccharomyces pombe)
Nitric oxide stimulates guanylate cyclase (Schizosaccharomyces pombe)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Schizosaccharomyces pombe)
NO [cytosol]
Immune System (Schizosaccharomyces pombe)
Innate Immune System (Schizosaccharomyces pombe)
ROS and RNS production in phagocytes (Schizosaccharomyces pombe)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Schizosaccharomyces pombe)
NO [cytosol]
Metabolism (Schizosaccharomyces pombe)
Aerobic respiration and respiratory electron transport (Schizosaccharomyces pombe)
Pyruvate metabolism (Schizosaccharomyces pombe)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Schizosaccharomyces pombe)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Schizosaccharomyces pombe)
eNOS activation (Schizosaccharomyces pombe)
eNOS synthesizes NO (Schizosaccharomyces pombe)
NO [cytosol]
Signal Transduction (Schizosaccharomyces pombe)
Signaling by Nuclear Receptors (Schizosaccharomyces pombe)
ESR-mediated signaling (Schizosaccharomyces pombe)
Extra-nuclear estrogen signaling (Schizosaccharomyces pombe)
eNOS synthesizes NO (Schizosaccharomyces pombe)
NO [cytosol]
Signaling by Receptor Tyrosine Kinases (Schizosaccharomyces pombe)
Signaling by VEGF (Schizosaccharomyces pombe)
VEGFA-VEGFR2 Pathway (Schizosaccharomyces pombe)
VEGFR2 mediated vascular permeability (Schizosaccharomyces pombe)
eNOS synthesizes NO (Schizosaccharomyces pombe)
NO [cytosol]
Hemostasis (Sus scrofa)
Platelet homeostasis (Sus scrofa)
Nitric oxide stimulates guanylate cyclase (Sus scrofa)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Sus scrofa)
NO [cytosol]
Immune System (Sus scrofa)
Innate Immune System (Sus scrofa)
ROS and RNS production in phagocytes (Sus scrofa)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Sus scrofa)
NO [cytosol]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Pyruvate metabolism (Sus scrofa)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Sus scrofa)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Sus scrofa)
eNOS activation (Sus scrofa)
CYGB dioxygenates NO (Sus scrofa)
NO [cytosol]
eNOS synthesizes NO (Sus scrofa)
NO [cytosol]
Muscle contraction (Sus scrofa)
Smooth Muscle Contraction (Sus scrofa)
Cinaciguat binds sGC:NO (Sus scrofa)
Guanylate cyclase:NO [cytosol] (Sus scrofa)
NO [cytosol]
NO:sGC:cinaciguat [cytosol] (Sus scrofa)
Guanylate cyclase:NO [cytosol] (Sus scrofa)
NO [cytosol]
sGC stimulators bind sGC:NO (Sus scrofa)
Guanylate cyclase:NO [cytosol] (Sus scrofa)
NO [cytosol]
NO:sGC:sGC stimulators [cytosol] (Sus scrofa)
Guanylate cyclase:NO [cytosol] (Sus scrofa)
NO [cytosol]
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
ESR-mediated signaling (Sus scrofa)
Extra-nuclear estrogen signaling (Sus scrofa)
eNOS synthesizes NO (Sus scrofa)
NO [cytosol]
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by VEGF (Sus scrofa)
VEGFA-VEGFR2 Pathway (Sus scrofa)
VEGFR2 mediated vascular permeability (Sus scrofa)
eNOS synthesizes NO (Sus scrofa)
NO [cytosol]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Pyruvate metabolism (Xenopus tropicalis)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Xenopus tropicalis)
NO [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Xenopus tropicalis)
eNOS activation (Xenopus tropicalis)
CYGB dioxygenates NO (Xenopus tropicalis)
NO [cytosol]
External Reference Information
External Reference
nitric oxide [ChEBI:16480]
Participates
as a component of
Guanylate cyclase, soluble:NO [cytosol] (Rattus norvegicus)
Guanylate cyclase:NO [cytosol] (Danio rerio)
Guanylate cyclase:NO [cytosol] (Bos taurus)
Guanylate cyclase:NO [cytosol] (Mus musculus)
Guanylate cyclase:NO [cytosol] (Sus scrofa)
Guanylate cyclase:NO [cytosol] (Canis familiaris)
Guanylate cyclase:NO [cytosol] (Rattus norvegicus)
Guanylate cyclase:NO [cytosol] (Gallus gallus)
Guanylate cyclase:NO [cytosol] (Drosophila melanogaster)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
as an input of
NO binds to Guanylate Cyclase (Rattus norvegicus)
NO binds to Guanylate Cyclase (Homo sapiens)
BIL scavenges NO (Homo sapiens)
Superoxide reacts rapidly with NO to form peroxynitrite (ONOO-) (Homo sapiens)
CYGB dioxygenates NO (Homo sapiens)
CYGB dioxygenates NO (Mus musculus)
CYGB dioxygenates NO (Rattus norvegicus)
CYGB dioxygenates NO (Canis familiaris)
CYGB dioxygenates NO (Bos taurus)
CYGB dioxygenates NO (Sus scrofa)
CYGB dioxygenates NO (Danio rerio)
CYGB dioxygenates NO (Xenopus tropicalis)
CYGB dioxygenates NO (Gallus gallus)
CYGB dioxygenates NO (Caenorhabditis elegans)
Superoxide and nitric oxide react to peroxynitrite (Homo sapiens)
NO and NO2 react to N2O3 (Homo sapiens)
Nitric oxide and O2 react to NO2 (Homo sapiens)
Nitric oxide diffuses into the phagosome (Homo sapiens)
Nitric oxide oxidizes to nitrosyl ion (Homo sapiens)
as an output of
eNOS synthesizes NO (Drosophila melanogaster)
eNOS synthesizes NO (Homo sapiens)
eNOS synthesizes NO (Mus musculus)
eNOS synthesizes NO (Rattus norvegicus)
eNOS synthesizes NO (Bos taurus)
eNOS synthesizes NO (Sus scrofa)
eNOS synthesizes NO (Gallus gallus)
eNOS synthesizes NO (Caenorhabditis elegans)
eNOS synthesizes NO (Dictyostelium discoideum)
eNOS synthesizes NO (Schizosaccharomyces pombe)
eNOS synthesizes NO (Saccharomyces cerevisiae)
eNOS synthesizes NO (Plasmodium falciparum)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Homo sapiens)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Mus musculus)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Rattus norvegicus)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Canis familiaris)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Bos taurus)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Sus scrofa)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Danio rerio)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Gallus gallus)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Drosophila melanogaster)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Dictyostelium discoideum)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Schizosaccharomyces pombe)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Saccharomyces cerevisiae)
Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Plasmodium falciparum)
Nitric oxide enters the bacterium (Homo sapiens)
Nitrogen dioxide is reduced to NO by F420 (Homo sapiens)
This entity regulates
Negatively
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Homo sapiens)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Plasmodium falciparum)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Saccharomyces cerevisiae)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Schizosaccharomyces pombe)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Dictyostelium discoideum)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Caenorhabditis elegans)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Drosophila melanogaster)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Gallus gallus)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Xenopus tropicalis)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Danio rerio)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Sus scrofa)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Bos taurus)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Canis familiaris)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Rattus norvegicus)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
(Mus musculus)
Positively
Soluble guanylate cyclase converts GTP to cGMP
(Homo sapiens)
Other forms of this molecule
NO [phagocytic vesicle lumen]
NO [mitochondrial matrix]
Cross References
Guide to Pharmacology - Ligands
2509
COMPOUND
C00533
HMDB Metabolite
HMDB0003378
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