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About
What is Reactome ?
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Team
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Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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(2Fe-2S)(1+) [mitochondrial matrix]
Stable Identifier
R-ALL-2395504
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
di-mu-sulfido-diiron(1+)
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Cytochrome P450 - arranged by substrate type (Bos taurus)
Endogenous sterols (Bos taurus)
CYP11A1 cleaves 20a,22b-DHCHOL (Bos taurus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Bos taurus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Bos taurus)
FDX1 (red.) [mitochondrial matrix] (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of lipids (Bos taurus)
Metabolism of steroids (Bos taurus)
Metabolism of steroid hormones (Bos taurus)
Pregnenolone biosynthesis (Bos taurus)
CYP11A1 cleaves 20a,22b-DHCHOL (Bos taurus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Bos taurus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Bos taurus)
FDX1 (red.) [mitochondrial matrix] (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Bos taurus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Bos taurus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Bos taurus)
FDX1 (red.) [mitochondrial matrix] (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Bos taurus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Bos taurus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Bos taurus)
FDX1 (red.) [mitochondrial matrix] (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of cofactors (Bos taurus)
Ubiquinol biosynthesis (Bos taurus)
COQ6 hydroxylates DHB (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Bos taurus)
Electron transport from NADPH to Ferredoxin (Bos taurus)
FDXR transfers electrons to FDX1,2 (FDX1L) (Bos taurus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Bos taurus)
FDX1 (red.) [mitochondrial matrix] (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Bos taurus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Bos taurus)
FDX1 (red.) [mitochondrial matrix] (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Protein lipoylation (Bos taurus)
LIAS synthesizes lipoyl-GCSH (Bos taurus)
FDX1 (red.) [mitochondrial matrix] (Bos taurus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of cofactors (Caenorhabditis elegans)
Ubiquinol biosynthesis (Caenorhabditis elegans)
COQ6 hydroxylates DHB (Caenorhabditis elegans)
(2Fe-2S)(1+) [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Caenorhabditis elegans)
Electron transport from NADPH to Ferredoxin (Caenorhabditis elegans)
FDXR transfers electrons to FDX1,2 (FDX1L) (Caenorhabditis elegans)
FDX2 (reduced) [mitochondrial matrix] (Caenorhabditis elegans)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Caenorhabditis elegans)
FDX2 (reduced) [mitochondrial matrix] (Caenorhabditis elegans)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Cytochrome P450 - arranged by substrate type (Canis familiaris)
Endogenous sterols (Canis familiaris)
CYP11A1 cleaves 20a,22b-DHCHOL (Canis familiaris)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Canis familiaris)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Canis familiaris)
FDX1 (red.) [mitochondrial matrix] (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of lipids (Canis familiaris)
Metabolism of steroids (Canis familiaris)
Metabolism of steroid hormones (Canis familiaris)
Pregnenolone biosynthesis (Canis familiaris)
CYP11A1 cleaves 20a,22b-DHCHOL (Canis familiaris)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Canis familiaris)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Canis familiaris)
FDX1 (red.) [mitochondrial matrix] (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Canis familiaris)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Canis familiaris)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Canis familiaris)
FDX1 (red.) [mitochondrial matrix] (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Canis familiaris)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Canis familiaris)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Canis familiaris)
FDX1 (red.) [mitochondrial matrix] (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of cofactors (Canis familiaris)
Ubiquinol biosynthesis (Canis familiaris)
COQ6 hydroxylates DHB (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Canis familiaris)
Electron transport from NADPH to Ferredoxin (Canis familiaris)
FDXR transfers electrons to FDX1,2 (FDX1L) (Canis familiaris)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Canis familiaris)
FDX1 (red.) [mitochondrial matrix] (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Canis familiaris)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Canis familiaris)
FDX1 (red.) [mitochondrial matrix] (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Protein lipoylation (Canis familiaris)
LIAS synthesizes lipoyl-GCSH (Canis familiaris)
FDX1 (red.) [mitochondrial matrix] (Canis familiaris)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
Cytochrome P450 - arranged by substrate type (Danio rerio)
Endogenous sterols (Danio rerio)
CYP11A1 cleaves 20a,22b-DHCHOL (Danio rerio)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Danio rerio)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Danio rerio)
FDX1 (red.) [mitochondrial matrix] (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of lipids (Danio rerio)
Metabolism of steroids (Danio rerio)
Metabolism of steroid hormones (Danio rerio)
Pregnenolone biosynthesis (Danio rerio)
CYP11A1 cleaves 20a,22b-DHCHOL (Danio rerio)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Danio rerio)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Danio rerio)
FDX1 (red.) [mitochondrial matrix] (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Danio rerio)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Danio rerio)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Danio rerio)
FDX1 (red.) [mitochondrial matrix] (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Danio rerio)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Danio rerio)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Danio rerio)
FDX1 (red.) [mitochondrial matrix] (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of cofactors (Danio rerio)
Ubiquinol biosynthesis (Danio rerio)
COQ6 hydroxylates DHB (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Danio rerio)
Electron transport from NADPH to Ferredoxin (Danio rerio)
FDXR transfers electrons to FDX1,2 (FDX1L) (Danio rerio)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Danio rerio)
FDX1 (red.) [mitochondrial matrix] (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Danio rerio)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Danio rerio)
FDX1 (red.) [mitochondrial matrix] (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Protein lipoylation (Danio rerio)
LIAS synthesizes lipoyl-GCSH (Danio rerio)
FDX1 (red.) [mitochondrial matrix] (Danio rerio)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of cofactors (Dictyostelium discoideum)
Ubiquinol biosynthesis (Dictyostelium discoideum)
COQ6 hydroxylates DHB (Dictyostelium discoideum)
(2Fe-2S)(1+) [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Dictyostelium discoideum)
Electron transport from NADPH to Ferredoxin (Dictyostelium discoideum)
FDXR transfers electrons to FDX1,2 (FDX1L) (Dictyostelium discoideum)
FDX2 (reduced) [mitochondrial matrix] (Dictyostelium discoideum)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Dictyostelium discoideum)
FDX2 (reduced) [mitochondrial matrix] (Dictyostelium discoideum)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of cofactors (Drosophila melanogaster)
Ubiquinol biosynthesis (Drosophila melanogaster)
COQ6 hydroxylates DHB (Drosophila melanogaster)
(2Fe-2S)(1+) [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Drosophila melanogaster)
Electron transport from NADPH to Ferredoxin (Drosophila melanogaster)
FDXR transfers electrons to FDX1,2 (FDX1L) (Drosophila melanogaster)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Drosophila melanogaster)
FDX1 (red.) [mitochondrial matrix] (Drosophila melanogaster)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Drosophila melanogaster)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Drosophila melanogaster)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Drosophila melanogaster)
FDX1 (red.) [mitochondrial matrix] (Drosophila melanogaster)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Drosophila melanogaster)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Protein lipoylation (Drosophila melanogaster)
LIAS synthesizes lipoyl-GCSH (Drosophila melanogaster)
FDX1 (red.) [mitochondrial matrix] (Drosophila melanogaster)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
Cytochrome P450 - arranged by substrate type (Gallus gallus)
Endogenous sterols (Gallus gallus)
CYP11A1 cleaves 20a,22b-DHCHOL (Gallus gallus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Gallus gallus)
FDX1 (red.) [mitochondrial matrix] (Gallus gallus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of lipids (Gallus gallus)
Metabolism of steroids (Gallus gallus)
Metabolism of steroid hormones (Gallus gallus)
Pregnenolone biosynthesis (Gallus gallus)
CYP11A1 cleaves 20a,22b-DHCHOL (Gallus gallus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Gallus gallus)
FDX1 (red.) [mitochondrial matrix] (Gallus gallus)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Gallus gallus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Gallus gallus)
FDX1 (red.) [mitochondrial matrix] (Gallus gallus)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Gallus gallus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Gallus gallus)
FDX1 (red.) [mitochondrial matrix] (Gallus gallus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of cofactors (Gallus gallus)
Ubiquinol biosynthesis (Gallus gallus)
COQ6 hydroxylates DHB (Gallus gallus)
(2Fe-2S)(1+) [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Gallus gallus)
Electron transport from NADPH to Ferredoxin (Gallus gallus)
FDXR transfers electrons to FDX1,2 (FDX1L) (Gallus gallus)
FDX1 (red.) [mitochondrial matrix] (Gallus gallus)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Gallus gallus)
FDX1 (red.) [mitochondrial matrix] (Gallus gallus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Protein lipoylation (Gallus gallus)
LIAS synthesizes lipoyl-GCSH (Gallus gallus)
FDX1 (red.) [mitochondrial matrix] (Gallus gallus)
(2Fe-2S)(1+) [mitochondrial matrix]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Metabolic disorders of biological oxidation enzymes (Homo sapiens)
Defective CYP11A1 causes AICSR (Homo sapiens)
Defective CYP11A1 does not cleave 20a,22b-DHCHOL (Homo sapiens)
CYP11A1 mutants:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Homo sapiens)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
FDX1 (red.) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Endogenous sterols (Homo sapiens)
CYP11A1 cleaves 20a,22b-DHCHOL (Homo sapiens)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Homo sapiens)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
FDX1 (red.) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Metabolism of steroid hormones (Homo sapiens)
Pregnenolone biosynthesis (Homo sapiens)
CYP11A1 cleaves 20a,22b-DHCHOL (Homo sapiens)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Homo sapiens)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
FDX1 (red.) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Homo sapiens)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Homo sapiens)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
FDX1 (red.) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Homo sapiens)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Homo sapiens)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
FDX1 (red.) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of cofactors (Homo sapiens)
Ubiquinol biosynthesis (Homo sapiens)
COQ6 hydroxylates DHB (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Homo sapiens)
Electron transport from NADPH to Ferredoxin (Homo sapiens)
FDXR transfers electrons to FDX1,2 (FDX1L) (Homo sapiens)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
FDX1 (red.) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Homo sapiens)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
FDX1 (red.) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Protein lipoylation (Homo sapiens)
LIAS synthesizes lipoyl-GCSH (Homo sapiens)
FDX1 (red.) [mitochondrial matrix] (Homo sapiens)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Endogenous sterols (Mus musculus)
CYP11A1 cleaves 20a,22b-DHCHOL (Mus musculus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Mus musculus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Mus musculus)
FDX1 (red.) [mitochondrial matrix] (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of lipids (Mus musculus)
Metabolism of steroids (Mus musculus)
Metabolism of steroid hormones (Mus musculus)
Pregnenolone biosynthesis (Mus musculus)
CYP11A1 cleaves 20a,22b-DHCHOL (Mus musculus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Mus musculus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Mus musculus)
FDX1 (red.) [mitochondrial matrix] (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Mus musculus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Mus musculus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Mus musculus)
FDX1 (red.) [mitochondrial matrix] (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Mus musculus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Mus musculus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Mus musculus)
FDX1 (red.) [mitochondrial matrix] (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of cofactors (Mus musculus)
Ubiquinol biosynthesis (Mus musculus)
COQ6 hydroxylates DHB (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Mus musculus)
Electron transport from NADPH to Ferredoxin (Mus musculus)
FDXR transfers electrons to FDX1,2 (FDX1L) (Mus musculus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Mus musculus)
FDX1 (red.) [mitochondrial matrix] (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Mus musculus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Mus musculus)
FDX1 (red.) [mitochondrial matrix] (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Protein lipoylation (Mus musculus)
LIAS synthesizes lipoyl-GCSH (Mus musculus)
FDX1 (red.) [mitochondrial matrix] (Mus musculus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Plasmodium falciparum)
Mitochondrial iron-sulfur cluster biogenesis (Plasmodium falciparum)
Electron transport from NADPH to Ferredoxin (Plasmodium falciparum)
FDXR transfers electrons to FDX1,2 (FDX1L) (Plasmodium falciparum)
FDX2 (reduced) [mitochondrial matrix] (Plasmodium falciparum)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Plasmodium falciparum)
FDX2 (reduced) [mitochondrial matrix] (Plasmodium falciparum)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Cytochrome P450 - arranged by substrate type (Rattus norvegicus)
Endogenous sterols (Rattus norvegicus)
CYP11A1 cleaves 20a,22b-DHCHOL (Rattus norvegicus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Rattus norvegicus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Rattus norvegicus)
FDX1 (red.) [mitochondrial matrix] (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of lipids (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Metabolism of steroid hormones (Rattus norvegicus)
Pregnenolone biosynthesis (Rattus norvegicus)
CYP11A1 cleaves 20a,22b-DHCHOL (Rattus norvegicus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Rattus norvegicus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Rattus norvegicus)
FDX1 (red.) [mitochondrial matrix] (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Rattus norvegicus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Rattus norvegicus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Rattus norvegicus)
FDX1 (red.) [mitochondrial matrix] (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Rattus norvegicus)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Rattus norvegicus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Rattus norvegicus)
FDX1 (red.) [mitochondrial matrix] (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of cofactors (Rattus norvegicus)
Ubiquinol biosynthesis (Rattus norvegicus)
COQ6 hydroxylates DHB (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Rattus norvegicus)
Electron transport from NADPH to Ferredoxin (Rattus norvegicus)
FDXR transfers electrons to FDX1,2 (FDX1L) (Rattus norvegicus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Rattus norvegicus)
FDX1 (red.) [mitochondrial matrix] (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Rattus norvegicus)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Rattus norvegicus)
FDX1 (red.) [mitochondrial matrix] (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Protein lipoylation (Rattus norvegicus)
LIAS synthesizes lipoyl-GCSH (Rattus norvegicus)
FDX1 (red.) [mitochondrial matrix] (Rattus norvegicus)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Metabolism of vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of cofactors (Saccharomyces cerevisiae)
Ubiquinol biosynthesis (Saccharomyces cerevisiae)
COQ6 hydroxylates DHB (Saccharomyces cerevisiae)
(2Fe-2S)(1+) [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Saccharomyces cerevisiae)
Electron transport from NADPH to Ferredoxin (Saccharomyces cerevisiae)
FDXR transfers electrons to FDX1,2 (FDX1L) (Saccharomyces cerevisiae)
FDX2 (reduced) [mitochondrial matrix] (Saccharomyces cerevisiae)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Saccharomyces cerevisiae)
FDX2 (reduced) [mitochondrial matrix] (Saccharomyces cerevisiae)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Metabolism of vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of cofactors (Schizosaccharomyces pombe)
Ubiquinol biosynthesis (Schizosaccharomyces pombe)
COQ6 hydroxylates DHB (Schizosaccharomyces pombe)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Cytochrome P450 - arranged by substrate type (Sus scrofa)
Endogenous sterols (Sus scrofa)
CYP11A1 cleaves 20a,22b-DHCHOL (Sus scrofa)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Sus scrofa)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Sus scrofa)
FDX1 (red.) [mitochondrial matrix] (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of lipids (Sus scrofa)
Metabolism of steroids (Sus scrofa)
Metabolism of steroid hormones (Sus scrofa)
Pregnenolone biosynthesis (Sus scrofa)
CYP11A1 cleaves 20a,22b-DHCHOL (Sus scrofa)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Sus scrofa)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Sus scrofa)
FDX1 (red.) [mitochondrial matrix] (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Sus scrofa)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Sus scrofa)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Sus scrofa)
FDX1 (red.) [mitochondrial matrix] (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Sus scrofa)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Sus scrofa)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Sus scrofa)
FDX1 (red.) [mitochondrial matrix] (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of cofactors (Sus scrofa)
Ubiquinol biosynthesis (Sus scrofa)
COQ6 hydroxylates DHB (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Sus scrofa)
Electron transport from NADPH to Ferredoxin (Sus scrofa)
FDXR transfers electrons to FDX1,2 (FDX1L) (Sus scrofa)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Sus scrofa)
FDX1 (red.) [mitochondrial matrix] (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Sus scrofa)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Sus scrofa)
FDX1 (red.) [mitochondrial matrix] (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Protein lipoylation (Sus scrofa)
LIAS synthesizes lipoyl-GCSH (Sus scrofa)
FDX1 (red.) [mitochondrial matrix] (Sus scrofa)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase I - Functionalization of compounds (Xenopus tropicalis)
Cytochrome P450 - arranged by substrate type (Xenopus tropicalis)
Endogenous sterols (Xenopus tropicalis)
CYP11A1 cleaves 20a,22b-DHCHOL (Xenopus tropicalis)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Xenopus tropicalis)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Xenopus tropicalis)
FDX1 (red.) [mitochondrial matrix] (Xenopus tropicalis)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Xenopus tropicalis)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of lipids (Xenopus tropicalis)
Metabolism of steroids (Xenopus tropicalis)
Metabolism of steroid hormones (Xenopus tropicalis)
Pregnenolone biosynthesis (Xenopus tropicalis)
CYP11A1 cleaves 20a,22b-DHCHOL (Xenopus tropicalis)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Xenopus tropicalis)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Xenopus tropicalis)
FDX1 (red.) [mitochondrial matrix] (Xenopus tropicalis)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Xenopus tropicalis)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Xenopus tropicalis)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Xenopus tropicalis)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Xenopus tropicalis)
FDX1 (red.) [mitochondrial matrix] (Xenopus tropicalis)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Xenopus tropicalis)
(2Fe-2S)(1+) [mitochondrial matrix]
Oxidation of cholesterol to 22beta-hydroxycholesterol (Xenopus tropicalis)
CYP11A1:FDXR:FDX1,FDX1L (red.) [mitochondrial matrix] (Xenopus tropicalis)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Xenopus tropicalis)
FDX1 (red.) [mitochondrial matrix] (Xenopus tropicalis)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Xenopus tropicalis)
(2Fe-2S)(1+) [mitochondrial matrix]
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of cofactors (Xenopus tropicalis)
Ubiquinol biosynthesis (Xenopus tropicalis)
COQ6 hydroxylates DHB (Xenopus tropicalis)
(2Fe-2S)(1+) [mitochondrial matrix]
Mitochondrial iron-sulfur cluster biogenesis (Xenopus tropicalis)
Electron transport from NADPH to Ferredoxin (Xenopus tropicalis)
FDXR transfers electrons to FDX1,2 (FDX1L) (Xenopus tropicalis)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Xenopus tropicalis)
FDX1 (red.) [mitochondrial matrix] (Xenopus tropicalis)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Xenopus tropicalis)
(2Fe-2S)(1+) [mitochondrial matrix]
FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Xenopus tropicalis)
FDX1,FDX2 (reduced) [mitochondrial matrix] (Xenopus tropicalis)
FDX1 (red.) [mitochondrial matrix] (Xenopus tropicalis)
(2Fe-2S)(1+) [mitochondrial matrix]
FDX2 (reduced) [mitochondrial matrix] (Xenopus tropicalis)
(2Fe-2S)(1+) [mitochondrial matrix]
External Reference Information
External Reference
di-mu-sulfido-diiron(1+) [ChEBI:33738]
Participates
as an input of
COQ6 hydroxylates DHB (Saccharomyces cerevisiae)
COQ6 hydroxylates DHB (Schizosaccharomyces pombe)
COQ6 hydroxylates DHB (Dictyostelium discoideum)
COQ6 hydroxylates DHB (Caenorhabditis elegans)
COQ6 hydroxylates DHB (Gallus gallus)
COQ6 hydroxylates DHB (Xenopus tropicalis)
COQ6 hydroxylates DHB (Danio rerio)
COQ6 hydroxylates DHB (Sus scrofa)
COQ6 hydroxylates DHB (Bos taurus)
COQ6 hydroxylates DHB (Canis familiaris)
COQ6 hydroxylates DHB (Rattus norvegicus)
COQ6 hydroxylates DHB (Mus musculus)
COQ6 hydroxylates DHB (Homo sapiens)
COQ6 hydroxylates DHB (Drosophila melanogaster)
as a component of
FDX2 (reduced) [mitochondrial matrix] (Caenorhabditis elegans)
FDX2 (reduced) [mitochondrial matrix] (Drosophila melanogaster)
FDX2 (reduced) [mitochondrial matrix] (Sus scrofa)
FDX2 (reduced) [mitochondrial matrix] (Rattus norvegicus)
FDX2 (reduced) [mitochondrial matrix] (Saccharomyces cerevisiae)
FDX2 (reduced) [mitochondrial matrix] (Xenopus tropicalis)
FDX2 (reduced) [mitochondrial matrix] (Canis familiaris)
FDX2 (reduced) [mitochondrial matrix] (Dictyostelium discoideum)
FDX2 (reduced) [mitochondrial matrix] (Bos taurus)
FDX2 (reduced) [mitochondrial matrix] (Mus musculus)
FDX2 (reduced) [mitochondrial matrix] (Danio rerio)
FDX2 (reduced) [mitochondrial matrix] (Plasmodium falciparum)
FDX2 (reduced) [mitochondrial matrix] (Homo sapiens)
FDX1 (red.) [mitochondrial matrix] (Gallus gallus)
FDX1 (red.) [mitochondrial matrix] (Mus musculus)
FDX1 (red.) [mitochondrial matrix] (Danio rerio)
FDX1 (red.) [mitochondrial matrix] (Bos taurus)
FDX1 (red.) [mitochondrial matrix] (Canis familiaris)
FDX1 (red.) [mitochondrial matrix] (Rattus norvegicus)
FDX1 (red.) [mitochondrial matrix] (Xenopus tropicalis)
FDX1 (red.) [mitochondrial matrix] (Sus scrofa)
FDX1 (red.) [mitochondrial matrix] (Drosophila melanogaster)
FDX1 (red.) [mitochondrial matrix] (Homo sapiens)
Other forms of this molecule
(2Fe-2S)(1+) [cytosol]
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