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ADP
Stable Identifier
R-ALL-29370
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Adenosine 5'-diphosphate
Locations in the PathwayBrowser for Species:
Homo sapiens
Arabidopsis thaliana
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Mycobacterium tuberculosis
Oryza sativa
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Taeniopygia guttata
Xenopus tropicalis
Expand all
Cell Cycle (Arabidopsis thaliana)
Cell Cycle, Mitotic (Arabidopsis thaliana)
M Phase (Arabidopsis thaliana)
Mitotic Prometaphase (Arabidopsis thaliana)
Condensation of Prometaphase Chromosomes (Arabidopsis thaliana)
CK2 phosphorylates condensin I subunits (Arabidopsis thaliana)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Arabidopsis thaliana)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Arabidopsis thaliana)
ADP [cytosol]
Cellular responses to external stimuli (Arabidopsis thaliana)
Cellular responses to stress (Arabidopsis thaliana)
Cellular response to heat stress (Arabidopsis thaliana)
Regulation of HSF1-mediated heat shock response (Arabidopsis thaliana)
Constitutive phosphorylation by pERK1/2 (Arabidopsis thaliana)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Arabidopsis thaliana)
ADP [cytosol]
HSP110s exchange ATP for ADP on HSP70s:ADP (Arabidopsis thaliana)
ADP [cytosol]
HSP70s:ADP [cytosol] (Arabidopsis thaliana)
HSPA1A:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Arabidopsis thaliana)
HSP70s:ADP [cytosol] (Arabidopsis thaliana)
HSPA1A:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) (Arabidopsis thaliana)
ATP binding to HSP90 triggers conformation change (Arabidopsis thaliana)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Arabidopsis thaliana)
HSP70:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Arabidopsis thaliana)
HSP70:ADP:nascent protein [cytosol] (Arabidopsis thaliana)
HSP70:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
ATP hydrolysis by HSP70 (Arabidopsis thaliana)
HSP40:HSP70:ADP:nascent protein [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Arabidopsis thaliana)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Arabidopsis thaliana)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Arabidopsis thaliana)
HSP70:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Arabidopsis thaliana)
HSP70:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Arabidopsis thaliana)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Arabidopsis thaliana)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Arabidopsis thaliana)
HSP70:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Arabidopsis thaliana)
HSP70:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Arabidopsis thaliana)
HSP40:HSP70:ADP:nascent protein [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Arabidopsis thaliana)
HSP70:ADP:nascent protein [cytosol] (Arabidopsis thaliana)
HSP70:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Arabidopsis thaliana)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Arabidopsis thaliana)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Arabidopsis thaliana)
HSP70:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Arabidopsis thaliana)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Arabidopsis thaliana)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Arabidopsis thaliana)
HSP70:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
Macroautophagy (Arabidopsis thaliana)
Beclin-1 complex phosphorylates PtdIns (Arabidopsis thaliana)
ADP [cytosol]
Developmental Biology (Arabidopsis thaliana)
Axon guidance (Arabidopsis thaliana)
L1CAM interactions (Arabidopsis thaliana)
Signal transduction by L1 (Arabidopsis thaliana)
MAP2K1 phosphorylates MAPK3 (Arabidopsis thaliana)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Arabidopsis thaliana)
ADP [cytosol]
NCAM signaling for neurite out-growth (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
RET signaling (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Hemostasis (Arabidopsis thaliana)
Factors involved in megakaryocyte development and platelet production (Arabidopsis thaliana)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Arabidopsis thaliana)
ADP [cytosol]
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Arabidopsis thaliana)
ADP [cytosol]
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Arabidopsis thaliana)
ADP [cytosol]
Kinesins (Arabidopsis thaliana)
Kinesins move along microtubules consuming ATP (Arabidopsis thaliana)
ADP [cytosol]
Platelet activation, signaling and aggregation (Arabidopsis thaliana)
Effects of PIP2 hydrolysis (Arabidopsis thaliana)
DAG kinase produces phosphatidic acid from DAG (Arabidopsis thaliana)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Arabidopsis thaliana)
Platelet degranulation (Arabidopsis thaliana)
ABCC4 accumulation of dense granule contents (Arabidopsis thaliana)
ADP [cytosol]
Immune System (Arabidopsis thaliana)
Adaptive Immune System (Arabidopsis thaliana)
Class I MHC mediated antigen processing & presentation (Arabidopsis thaliana)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Arabidopsis thaliana)
Transport of Antigen peptide in to ER (Arabidopsis thaliana)
ADP [cytosol]
Costimulation by the CD28 family (Arabidopsis thaliana)
CD28 co-stimulation (Arabidopsis thaliana)
CD28 dependent PI3K/Akt signaling (Arabidopsis thaliana)
p-S400-Cot phosphorylates NIK (Arabidopsis thaliana)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Arabidopsis thaliana)
Downstream signaling events of B Cell Receptor (BCR) (Arabidopsis thaliana)
PIP3 activates AKT signaling (Arabidopsis thaliana)
Negative regulation of the PI3K/AKT network (Arabidopsis thaliana)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Arabidopsis thaliana)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
Cytokine Signaling in Immune system (Arabidopsis thaliana)
Signaling by Interleukins (Arabidopsis thaliana)
Interleukin-17 signaling (Arabidopsis thaliana)
MAPK1/MAPK3 signaling (Arabidopsis thaliana)
RAF-independent MAPK1/3 activation (Arabidopsis thaliana)
MAPK1 (ERK2) activation (Arabidopsis thaliana)
MAP2K2 phosphorylates MAPK1 (Arabidopsis thaliana)
ADP [cytosol]
MAPK3 (ERK1) activation (Arabidopsis thaliana)
Inactivation of MAP2K1 by CDK1 (Arabidopsis thaliana)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Arabidopsis thaliana)
ADP [cytosol]
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Interleukin-19,20,22,24,26,28 and 29 signaling (Arabidopsis thaliana)
MAPK1/MAPK3 signaling (Arabidopsis thaliana)
RAF-independent MAPK1/3 activation (Arabidopsis thaliana)
MAPK1 (ERK2) activation (Arabidopsis thaliana)
MAP2K2 phosphorylates MAPK1 (Arabidopsis thaliana)
ADP [cytosol]
MAPK3 (ERK1) activation (Arabidopsis thaliana)
Inactivation of MAP2K1 by CDK1 (Arabidopsis thaliana)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Arabidopsis thaliana)
ADP [cytosol]
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Interleukin-2 family signaling (Arabidopsis thaliana)
Interleukin receptor SHC signaling (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Interleukin-3, 5 and GM-CSF signaling (Arabidopsis thaliana)
Interleukin receptor SHC signaling (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Interleukin-7 signaling (Arabidopsis thaliana)
PIP3 activates AKT signaling (Arabidopsis thaliana)
Negative regulation of the PI3K/AKT network (Arabidopsis thaliana)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Arabidopsis thaliana)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
TNFR2 non-canonical NF-kB pathway (Arabidopsis thaliana)
NIK-->noncanonical NF-kB signaling (Arabidopsis thaliana)
NIK autophosphorylates on T559 (Arabidopsis thaliana)
ADP [cytosol]
Innate Immune System (Arabidopsis thaliana)
DAP12 interactions (Arabidopsis thaliana)
DAP12 signaling (Arabidopsis thaliana)
PIP3 activates AKT signaling (Arabidopsis thaliana)
Negative regulation of the PI3K/AKT network (Arabidopsis thaliana)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Arabidopsis thaliana)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Arabidopsis thaliana)
FCERI mediated MAPK activation (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Role of LAT2/NTAL/LAB on calcium mobilization (Arabidopsis thaliana)
PIP3 activates AKT signaling (Arabidopsis thaliana)
Negative regulation of the PI3K/AKT network (Arabidopsis thaliana)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Arabidopsis thaliana)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Arabidopsis thaliana)
Regulation of actin dynamics for phagocytic cup formation (Arabidopsis thaliana)
Branching and elongation of mother and daughter filaments (Arabidopsis thaliana)
Mother filament:ARP2/3:actin:ADP [cytosol] (Arabidopsis thaliana)
Actin:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
Metabolism (Arabidopsis thaliana)
Biological oxidations (Arabidopsis thaliana)
Phase II - Conjugation of compounds (Arabidopsis thaliana)
Cytosolic sulfonation of small molecules (Arabidopsis thaliana)
Transport and synthesis of PAPS (Arabidopsis thaliana)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Arabidopsis thaliana)
ADP [cytosol]
Glutathione conjugation (Arabidopsis thaliana)
Glutathione synthesis and recycling (Arabidopsis thaliana)
GSS:Mg2+ dimer synthesizes GSH (Arabidopsis thaliana)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Arabidopsis thaliana)
ADP [cytosol]
Inositol phosphate metabolism (Arabidopsis thaliana)
Synthesis of IP3 and IP4 in the cytosol (Arabidopsis thaliana)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Arabidopsis thaliana)
ADP [cytosol]
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Arabidopsis thaliana)
ADP [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Arabidopsis thaliana)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Arabidopsis thaliana)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Arabidopsis thaliana)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Arabidopsis thaliana)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Arabidopsis thaliana)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Arabidopsis thaliana)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Arabidopsis thaliana)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Arabidopsis thaliana)
ADP [cytosol]
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Arabidopsis thaliana)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Arabidopsis thaliana)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Arabidopsis thaliana)
ADP [cytosol]
Metabolism of amino acids and derivatives (Arabidopsis thaliana)
Amino acid synthesis and interconversion (transamination) (Arabidopsis thaliana)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Arabidopsis thaliana)
ADP [cytosol]
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Arabidopsis thaliana)
ADP [cytosol]
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Arabidopsis thaliana)
ADP [cytosol]
Metabolism of carbohydrates (Arabidopsis thaliana)
Catabolism of glucuronate to xylulose-5-phosphate (Arabidopsis thaliana)
XYLB phosphorylates D-xylulose (Arabidopsis thaliana)
ADP [cytosol]
Fructose metabolism (Arabidopsis thaliana)
Fructose catabolism (Arabidopsis thaliana)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Arabidopsis thaliana)
ADP [cytosol]
Glucose metabolism (Arabidopsis thaliana)
Gluconeogenesis (Arabidopsis thaliana)
ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate (Arabidopsis thaliana)
ADP [cytosol]
Glycolysis (Arabidopsis thaliana)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP (Arabidopsis thaliana)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Arabidopsis thaliana)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Arabidopsis thaliana)
ADP [cytosol]
HK1,2,3,GCK phosphorylate Glc to form G6P (Arabidopsis thaliana)
ADP [cytosol]
phosphoenolpyruvate + ADP => pyruvate + ATP (Arabidopsis thaliana)
ADP [cytosol]
Glycosaminoglycan metabolism (Arabidopsis thaliana)
Transport and synthesis of PAPS (Arabidopsis thaliana)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Arabidopsis thaliana)
ADP [cytosol]
Pentose phosphate pathway (hexose monophosphate shunt) (Arabidopsis thaliana)
RBKS phosphorylates ribose to R5P (Arabidopsis thaliana)
ADP [cytosol]
Metabolism of lipids (Arabidopsis thaliana)
Fatty acid metabolism (Arabidopsis thaliana)
Fatty acyl-CoA biosynthesis (Arabidopsis thaliana)
ACLY tetramer transforms CIT to Ac-CoA (Arabidopsis thaliana)
ADP [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Arabidopsis thaliana)
ADP [cytosol]
Import of palmitoyl-CoA into the mitochondrial matrix (Arabidopsis thaliana)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Arabidopsis thaliana)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Arabidopsis thaliana)
ADP [cytosol]
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Arabidopsis thaliana)
ADP [cytosol]
Metabolism of steroids (Arabidopsis thaliana)
Bile acid and bile salt metabolism (Arabidopsis thaliana)
Recycling of bile acids and salts (Arabidopsis thaliana)
ABCB11 transports bile salts from cytosol to extracellular region (Arabidopsis thaliana)
ADP [cytosol]
Synthesis of bile acids and bile salts (Arabidopsis thaliana)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Arabidopsis thaliana)
ABCB11 transports bile salts from cytosol to extracellular region (Arabidopsis thaliana)
ADP [cytosol]
Cholesterol biosynthesis (Arabidopsis thaliana)
MVD decarboxylates MVA5PP to IPPP (Arabidopsis thaliana)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Arabidopsis thaliana)
ADP [cytosol]
Phospholipid metabolism (Arabidopsis thaliana)
Glycerophospholipid biosynthesis (Arabidopsis thaliana)
Synthesis of PC (Arabidopsis thaliana)
Cho is phosphorylated to PCho by CHK dimer (Arabidopsis thaliana)
ADP [cytosol]
Synthesis of PE (Arabidopsis thaliana)
ETA is phosphorylated to PETA by CHK/ETNK (Arabidopsis thaliana)
ADP [cytosol]
PI Metabolism (Arabidopsis thaliana)
Synthesis of PIPs at the ER membrane (Arabidopsis thaliana)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Arabidopsis thaliana)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Arabidopsis thaliana)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Arabidopsis thaliana)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Arabidopsis thaliana)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Arabidopsis thaliana)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Arabidopsis thaliana)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Arabidopsis thaliana)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
Sphingolipid metabolism (Arabidopsis thaliana)
Glycosphingolipid metabolism (Arabidopsis thaliana)
CERK phosphorylates CERA to form C1P (Arabidopsis thaliana)
ADP [cytosol]
Sphingolipid de novo biosynthesis (Arabidopsis thaliana)
sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP (Arabidopsis thaliana)
ADP [cytosol]
sphingosine +ATP => sphingosine 1-phosphate + ADP (Arabidopsis thaliana)
ADP [cytosol]
Triglyceride metabolism (Arabidopsis thaliana)
Triglyceride biosynthesis (Arabidopsis thaliana)
Conversion of Glycerol to Glycerol-3-phosphate (Arabidopsis thaliana)
ADP [cytosol]
Metabolism of nucleotides (Arabidopsis thaliana)
Interconversion of nucleotide di- and triphosphates (Arabidopsis thaliana)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Arabidopsis thaliana)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Arabidopsis thaliana)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Arabidopsis thaliana)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Arabidopsis thaliana)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Arabidopsis thaliana)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Arabidopsis thaliana)
ADP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Arabidopsis thaliana)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Arabidopsis thaliana)
ADP [cytosol]
NMEs phosphorylate NDPs to NTPs (Arabidopsis thaliana)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Arabidopsis thaliana)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Arabidopsis thaliana)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Arabidopsis thaliana)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Arabidopsis thaliana)
ADP [cytosol]
Nucleobase biosynthesis (Arabidopsis thaliana)
Purine ribonucleoside monophosphate biosynthesis (Arabidopsis thaliana)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Arabidopsis thaliana)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Arabidopsis thaliana)
ADP [cytosol]
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Arabidopsis thaliana)
ADP [cytosol]
Pyrimidine biosynthesis (Arabidopsis thaliana)
L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate (Arabidopsis thaliana)
ADP [cytosol]
Nucleotide salvage (Arabidopsis thaliana)
Purine salvage (Arabidopsis thaliana)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Arabidopsis thaliana)
ADP [cytosol]
Pyrimidine salvage (Arabidopsis thaliana)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Arabidopsis thaliana)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Arabidopsis thaliana)
ADP [cytosol]
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Arabidopsis thaliana)
ADP [cytosol]
Metabolism of vitamins and cofactors (Arabidopsis thaliana)
Metabolism of water-soluble vitamins and cofactors (Arabidopsis thaliana)
Metabolism of folate and pterines (Arabidopsis thaliana)
Conversion of cytosolic 5-methyltetrahydrofolate (5-methylTHF) to 5-methylTHF-polyglutamate (Arabidopsis thaliana)
ADP [cytosol]
Conversion of cytosolic THF to THF-polyglutamate (Arabidopsis thaliana)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Arabidopsis thaliana)
ADP [cytosol]
Nicotinate metabolism (Arabidopsis thaliana)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Arabidopsis thaliana)
ADP [cytosol]
Vitamins B6 activation to pyridoxal phosphate (Arabidopsis thaliana)
2xPDKX:2xZn2+ phosphorylates PDX (Arabidopsis thaliana)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Arabidopsis thaliana)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Arabidopsis thaliana)
ADP [cytosol]
The citric acid (TCA) cycle and respiratory electron transport (Arabidopsis thaliana)
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Arabidopsis thaliana)
Mitochondrial Uncoupling Proteins (Arabidopsis thaliana)
The proton buffering model (Arabidopsis thaliana)
Protons are translocated from the intermembrane space to the matrix (Arabidopsis thaliana)
Purine nucleotide [cytosol]
ADP [cytosol]
Metabolism of RNA (Arabidopsis thaliana)
Nonsense-Mediated Decay (NMD) (Arabidopsis thaliana)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Arabidopsis thaliana)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Arabidopsis thaliana)
ADP [cytosol]
Metabolism of proteins (Arabidopsis thaliana)
Post-translational protein modification (Arabidopsis thaliana)
Asparagine N-linked glycosylation (Arabidopsis thaliana)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Arabidopsis thaliana)
Synthesis of substrates in N-glycan biosythesis (Arabidopsis thaliana)
GDP-fucose biosynthesis (Arabidopsis thaliana)
FUK phosphorylates beta-Fuc to Fuc1P (Arabidopsis thaliana)
ADP [cytosol]
Synthesis of Dolichyl-phosphate (Arabidopsis thaliana)
MVD decarboxylates MVA5PP to IPPP (Arabidopsis thaliana)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Arabidopsis thaliana)
ER to Golgi Anterograde Transport (Arabidopsis thaliana)
COPI-mediated anterograde transport (Arabidopsis thaliana)
GBF1 stimulates ARF nucleotide exchange (Arabidopsis thaliana)
ADP [cytosol]
Gamma carboxylation, hypusine formation and arylsulfatase activation (Arabidopsis thaliana)
FN3K phosphorylates ketosamines (Arabidopsis thaliana)
ADP [cytosol]
FN3KRP phosphorylates PsiAm, RibAm (Arabidopsis thaliana)
ADP [cytosol]
Protein folding (Arabidopsis thaliana)
Chaperonin-mediated protein folding (Arabidopsis thaliana)
Association of TriC/CCT with target proteins during biosynthesis (Arabidopsis thaliana)
Association of CCT/TriC with sphingosine kinase 1 (Arabidopsis thaliana)
CCT/TRiC:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
CCT/TRiC:ADP:Sphingosine kinase 1 [cytosol] (Arabidopsis thaliana)
CCT/TRiC:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Arabidopsis thaliana)
ATP binds G-protein beta associated TRiC/CCT (Arabidopsis thaliana)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Arabidopsis thaliana)
CCT/TRiC:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Arabidopsis thaliana)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Arabidopsis thaliana)
CCT/TRiC:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Arabidopsis thaliana)
CCT/TRiC:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Arabidopsis thaliana)
CCT/TRiC:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
Surfactant metabolism (Arabidopsis thaliana)
ABCA3 transports PC, PG from ER membrane to lamellar body (Arabidopsis thaliana)
ADP [cytosol]
Translation (Arabidopsis thaliana)
Eukaryotic Translation Initiation (Arabidopsis thaliana)
Cap-dependent Translation Initiation (Arabidopsis thaliana)
Ribosomal scanning and start codon recognition (Arabidopsis thaliana)
Ribosomal scanning (Arabidopsis thaliana)
ADP [cytosol]
Unfolded Protein Response (UPR) (Arabidopsis thaliana)
IRE1alpha activates chaperones (Arabidopsis thaliana)
IRE1 dimer autophosphorylates (Arabidopsis thaliana)
ADP [cytosol]
XBP1(S) activates chaperone genes (Arabidopsis thaliana)
ASNA1 transports TA proteins from cytosol to ER membrane (Arabidopsis thaliana)
ADP [cytosol]
Neuronal System (Arabidopsis thaliana)
Transmission across Chemical Synapses (Arabidopsis thaliana)
Neurotransmitter receptors and postsynaptic signal transmission (Arabidopsis thaliana)
Activation of NMDA receptor and postsynaptic events (Arabidopsis thaliana)
Post NMDA receptor activation events (Arabidopsis thaliana)
CREB phosphorylation through the activation of CaMKK (Arabidopsis thaliana)
Activation of CaMKK (Arabidopsis thaliana)
ADP [cytosol]
CREB phosphorylation through the activation of Ras (Arabidopsis thaliana)
Activation of MAPK (Arabidopsis thaliana)
ADP [cytosol]
RSK activation (Arabidopsis thaliana)
Phosphorylation by MAPK/ERK (Arabidopsis thaliana)
ADP [cytosol]
Neurotransmitter uptake and metabolism In glial cells (Arabidopsis thaliana)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Arabidopsis thaliana)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Arabidopsis thaliana)
ADP [cytosol]
Signal Transduction (Arabidopsis thaliana)
MAPK family signaling cascades (Arabidopsis thaliana)
MAPK1/MAPK3 signaling (Arabidopsis thaliana)
RAF-independent MAPK1/3 activation (Arabidopsis thaliana)
MAPK1 (ERK2) activation (Arabidopsis thaliana)
MAP2K2 phosphorylates MAPK1 (Arabidopsis thaliana)
ADP [cytosol]
MAPK3 (ERK1) activation (Arabidopsis thaliana)
Inactivation of MAP2K1 by CDK1 (Arabidopsis thaliana)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Arabidopsis thaliana)
ADP [cytosol]
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
PIP3 activates AKT signaling (Arabidopsis thaliana)
Negative regulation of the PI3K/AKT network (Arabidopsis thaliana)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Arabidopsis thaliana)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
Signaling by EGFR (Arabidopsis thaliana)
GAB1 signalosome (Arabidopsis thaliana)
PIP3 activates AKT signaling (Arabidopsis thaliana)
Negative regulation of the PI3K/AKT network (Arabidopsis thaliana)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Arabidopsis thaliana)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
GRB2 events in EGFR signaling (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
SHC1 events in EGFR signaling (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Signaling by GPCR (Arabidopsis thaliana)
GPCR downstream signaling (Arabidopsis thaliana)
G alpha (q) signalling events (Arabidopsis thaliana)
Effects of PIP2 hydrolysis (Arabidopsis thaliana)
DAG kinase produces phosphatidic acid from DAG (Arabidopsis thaliana)
ADP [cytosol]
Gastrin-CREB signalling pathway via PKC and MAPK (Arabidopsis thaliana)
G alpha (q) signalling events (Arabidopsis thaliana)
Effects of PIP2 hydrolysis (Arabidopsis thaliana)
DAG kinase produces phosphatidic acid from DAG (Arabidopsis thaliana)
ADP [cytosol]
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Signaling by Insulin receptor (Arabidopsis thaliana)
Insulin receptor signalling cascade (Arabidopsis thaliana)
IRS-mediated signalling (Arabidopsis thaliana)
PI3K Cascade (Arabidopsis thaliana)
PKB-mediated events (Arabidopsis thaliana)
mTOR signalling (Arabidopsis thaliana)
mTORC1-mediated signalling (Arabidopsis thaliana)
Phosphorylation and activation of eIF4G by activated S6K1 (Arabidopsis thaliana)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Arabidopsis thaliana)
ADP [cytosol]
SOS-mediated signalling (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Signaling by Leptin (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Signaling by PDGF (Arabidopsis thaliana)
Downstream signal transduction (Arabidopsis thaliana)
PIP3 activates AKT signaling (Arabidopsis thaliana)
Negative regulation of the PI3K/AKT network (Arabidopsis thaliana)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Arabidopsis thaliana)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Signaling by Rho GTPases (Arabidopsis thaliana)
RHO GTPase Effectors (Arabidopsis thaliana)
RHO GTPases Activate WASPs and WAVEs (Arabidopsis thaliana)
Branching and elongation of mother and daughter filaments (Arabidopsis thaliana)
Mother filament:ARP2/3:actin:ADP [cytosol] (Arabidopsis thaliana)
Actin:ADP [cytosol] (Arabidopsis thaliana)
ADP [cytosol]
Signaling by SCF-KIT (Arabidopsis thaliana)
PIP3 activates AKT signaling (Arabidopsis thaliana)
Negative regulation of the PI3K/AKT network (Arabidopsis thaliana)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Arabidopsis thaliana)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Arabidopsis thaliana)
IGF1R signaling cascade (Arabidopsis thaliana)
IRS-related events triggered by IGF1R (Arabidopsis thaliana)
IRS-mediated signalling (Arabidopsis thaliana)
PI3K Cascade (Arabidopsis thaliana)
PKB-mediated events (Arabidopsis thaliana)
mTOR signalling (Arabidopsis thaliana)
mTORC1-mediated signalling (Arabidopsis thaliana)
Phosphorylation and activation of eIF4G by activated S6K1 (Arabidopsis thaliana)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Arabidopsis thaliana)
ADP [cytosol]
SOS-mediated signalling (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Signaling by VEGF (Arabidopsis thaliana)
VEGFA-VEGFR2 Pathway (Arabidopsis thaliana)
VEGFR2 mediated cell proliferation (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Signaling by Wnt (Arabidopsis thaliana)
Beta-catenin independent WNT signaling (Arabidopsis thaliana)
Ca2+ pathway (Arabidopsis thaliana)
Autophosphorylation and activation of CAMK2 (Arabidopsis thaliana)
ADP [cytosol]
Dissociation of CaM and CAMK2 autophosphorylation (Arabidopsis thaliana)
ADP [cytosol]
Signalling by NGF (Arabidopsis thaliana)
NGF signalling via TRKA from the plasma membrane (Arabidopsis thaliana)
PI3K/AKT activation (Arabidopsis thaliana)
PIP3 activates AKT signaling (Arabidopsis thaliana)
Negative regulation of the PI3K/AKT network (Arabidopsis thaliana)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Arabidopsis thaliana)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
Signalling to ERKs (Arabidopsis thaliana)
Prolonged ERK activation events (Arabidopsis thaliana)
ARMS-mediated activation (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Frs2-mediated activation (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Signalling to RAS (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Signalling to p38 via RIT and RIN (Arabidopsis thaliana)
RAF/MAP kinase cascade (Arabidopsis thaliana)
MAP2K and MAPK activation (Arabidopsis thaliana)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Arabidopsis thaliana)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Arabidopsis thaliana)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Arabidopsis thaliana)
ADP [cytosol]
Negative regulation of MAPK pathway (Arabidopsis thaliana)
Negative feedback regulation of MAPK pathway (Arabidopsis thaliana)
Activated MAPK phosphorylates RAF1 (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Arabidopsis thaliana)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Arabidopsis thaliana)
ADP [cytosol]
Visual phototransduction (Arabidopsis thaliana)
The canonical retinoid cycle in rods (twilight vision) (Arabidopsis thaliana)
ABCA4 mediates atRAL transport (Arabidopsis thaliana)
ADP [cytosol]
Transport of small molecules (Arabidopsis thaliana)
ABC-family proteins mediated transport (Arabidopsis thaliana)
ABC transporters in lipid homeostasis (Arabidopsis thaliana)
ABCA12 transports lipids from cytosol to extracellular region (Arabidopsis thaliana)
ADP [cytosol]
ABCA3 transports PC, PG from ER membrane to lamellar body (Arabidopsis thaliana)
ADP [cytosol]
ABCA5 transports CHOL from lysosomal lumen to cytosol (Arabidopsis thaliana)
ADP [cytosol]
ABCAs mediate lipid efflux (Arabidopsis thaliana)
ADP [cytosol]
ABCAs mediate lipid influx (Arabidopsis thaliana)
ADP [cytosol]
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Arabidopsis thaliana)
ADP [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Arabidopsis thaliana)
ADP [cytosol]
ABCA4 mediates atRAL transport (Arabidopsis thaliana)
ADP [cytosol]
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Arabidopsis thaliana)
ADP [cytosol]
ABCB4 transports PC from plasma membrane to extracellular region (Arabidopsis thaliana)
ADP [cytosol]
ABCB9 transports peptides from cytosol to lysosomal lumen (Arabidopsis thaliana)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Arabidopsis thaliana)
ADP [cytosol]
HCO3- transport through ion channel (Arabidopsis thaliana)
ADP [cytosol]
The ABCC family mediates organic anion transport (Arabidopsis thaliana)
ADP [cytosol]
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Arabidopsis thaliana)
ADP [cytosol]
Ion channel transport (Arabidopsis thaliana)
Ion transport by P-type ATPases (Arabidopsis thaliana)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Arabidopsis thaliana)
ADP [cytosol]
ATP7B transports cytosolic Cu2+ to Golgi lumen (Arabidopsis thaliana)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Arabidopsis thaliana)
ADP [cytosol]
Iron uptake and transport (Arabidopsis thaliana)
Transferrin endocytosis and recycling (Arabidopsis thaliana)
Acidification of Tf:TfR1 containing endosome (Arabidopsis thaliana)
ADP [cytosol]
Vesicle-mediated transport (Arabidopsis thaliana)
Membrane Trafficking (Arabidopsis thaliana)
Clathrin-mediated endocytosis (Arabidopsis thaliana)
AAK1 phosphorylates AP-2 mu subunit at T156 (Arabidopsis thaliana)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Arabidopsis thaliana)
ADP [cytosol]
ER to Golgi Anterograde Transport (Arabidopsis thaliana)
COPI-mediated anterograde transport (Arabidopsis thaliana)
GBF1 stimulates ARF nucleotide exchange (Arabidopsis thaliana)
ADP [cytosol]
Cell Cycle (Bos taurus)
Cell Cycle Checkpoints (Bos taurus)
G2/M Checkpoints (Bos taurus)
G2/M DNA replication checkpoint (Bos taurus)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Bos taurus)
ADP [cytosol]
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Prometaphase (Bos taurus)
Condensation of Prometaphase Chromosomes (Bos taurus)
CK2 phosphorylates condensin I subunits (Bos taurus)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)
ADP [cytosol]
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Bos taurus)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Bos taurus)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at chromosomal arms (Bos taurus)
ADP [cytosol]
Mitotic Prophase (Bos taurus)
Golgi Cisternae Pericentriolar Stack Reorganization (Bos taurus)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Bos taurus)
ADP [cytosol]
PLK1 phosphorylates GORASP1 (Bos taurus)
ADP [cytosol]
Nuclear Envelope Breakdown (Bos taurus)
Activation of NIMA Kinases NEK9, NEK6, NEK7 (Bos taurus)
CDK1:CCNB phosphorylates NEK9 (Bos taurus)
ADP [cytosol]
NEK9 phosphorylates NEK6/NEK7 (Bos taurus)
ADP [cytosol]
PLK1 phosphorylates NEK9 (Bos taurus)
ADP [cytosol]
Nuclear Pore Complex (NPC) Disassembly (Bos taurus)
CDK1 phosphorylates NUP98 (Bos taurus)
ADP [cytosol]
NEK6/NEK7 phosphorylates NUP98 (Bos taurus)
ADP [cytosol]
Mitotic G1-G1/S phases (Bos taurus)
G1 Phase (Bos taurus)
Cyclin D associated events in G1 (Bos taurus)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Bos taurus)
ADP [cytosol]
G1/S Transition (Bos taurus)
Cyclin E associated events during G1/S transition (Bos taurus)
AKT phosphorylates p21Cip1 and p27Kip1 (Bos taurus)
ADP [cytosol]
SCF(Skp2)-mediated degradation of p27/p21 (Bos taurus)
PTK6 phosphorylates CDKN1B (Bos taurus)
ADP [cytosol]
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
AURKA Activation by TPX2 (Bos taurus)
TPX2 promotes AURKA autophosphorylation (Bos taurus)
ADP [cytosol]
Centrosome maturation (Bos taurus)
Loss of proteins required for interphase microtubule organization from the centrosome (Bos taurus)
Loss of Nlp from mitotic centrosomes (Bos taurus)
Plk1-mediated phosphorylation of Nlp (Bos taurus)
ADP [cytosol]
Cyclin A/B1/B2 associated events during G2/M transition (Bos taurus)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Bos taurus)
ADP [cytosol]
Phosphorylation of Cyclin B1 in the CRS domain (Bos taurus)
ADP [cytosol]
Interaction between PHLDA1 and AURKA (Bos taurus)
AURKA phosphorylates PHLDA1 (Bos taurus)
ADP [cytosol]
Polo-like kinase mediated events (Bos taurus)
Activation of Cdc25C (Bos taurus)
ADP [cytosol]
Regulation of PLK1 Activity at G2/M Transition (Bos taurus)
AJUBA facilitates AURKA autophosphorylation (Bos taurus)
ADP [cytosol]
AURKA phosphorylates PLK1 (Bos taurus)
ADP [cytosol]
CDK1 phosphorylates BORA (Bos taurus)
ADP [cytosol]
PLK1 phosphorylates BORA (Bos taurus)
ADP [cytosol]
PLK1 phosphorylates OPTN (Bos taurus)
ADP [cytosol]
The role of GTSE1 in G2/M progression after G2 checkpoint (Bos taurus)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Bos taurus)
ADP [cytosol]
PLK1 phosphorylates GTSE1 (Bos taurus)
ADP [cytosol]
S Phase (Bos taurus)
Cyclin A:Cdk2-associated events at S phase entry (Bos taurus)
SCF(Skp2)-mediated degradation of p27/p21 (Bos taurus)
PTK6 phosphorylates CDKN1B (Bos taurus)
ADP [cytosol]
Cell-Cell communication (Bos taurus)
Nephrin family interactions (Bos taurus)
Phosphorylation of nephrin by FYN (Bos taurus)
ADP [cytosol]
Cellular responses to external stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular Senescence (Bos taurus)
Oxidative Stress Induced Senescence (Bos taurus)
MAP3K5 phosphorylates MKK3 and MKK6 (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
Cellular response to heat stress (Bos taurus)
Regulation of HSF1-mediated heat shock response (Bos taurus)
Constitutive phosphorylation by pERK1/2 (Bos taurus)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Bos taurus)
ADP [cytosol]
HSP110s exchange ATP for ADP on HSP70s:ADP (Bos taurus)
ADP [cytosol]
HSP70s:ADP [cytosol] (Bos taurus)
HSPA1A:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Bos taurus)
HSP70s:ADP [cytosol] (Bos taurus)
HSPA1A:ADP [cytosol] (Bos taurus)
ADP [cytosol]
MAPKAPK2 phosphorylates HSF1 (Bos taurus)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) (Bos taurus)
ATP binding to HSP90 triggers conformation change (Bos taurus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
ATP hydrolysis by HSP70 (Bos taurus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Bos taurus)
ADP [cytosol]
FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Bos taurus)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Bos taurus)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Bos taurus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Bos taurus)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Bos taurus)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Bos taurus)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
Macroautophagy (Bos taurus)
AMPK (complex) phosphorylates ULK1 (complex) (Bos taurus)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Bos taurus)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Bos taurus)
ADP [cytosol]
ULK1 phosphorylates AMBRA1:Beclin-1 complex (Bos taurus)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Bos taurus)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Bos taurus)
ADP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the mTORC1 complex (Bos taurus)
ADP [cytosol]
Developmental Biology (Bos taurus)
Axon guidance (Bos taurus)
EPH-Ephrin signaling (Bos taurus)
EPH receptors autophosphorylate (Bos taurus)
ADP [cytosol]
EPH-ephrin mediated repulsion of cells (Bos taurus)
SFKs phosphorylate VAV2,3 (Bos taurus)
ADP [cytosol]
EPHB-mediated forward signaling (Bos taurus)
EPHB phosphorylates TIAM1 (Bos taurus)
ADP [cytosol]
PAK1 autophosphorylates (Bos taurus)
ADP [cytosol]
p-EPHB phosphorylates SDC2 (Bos taurus)
ADP [cytosol]
Ephrin signaling (Bos taurus)
PAKs autophosphorylate (Bos taurus)
ADP [cytosol]
PAKs phosphorylate MLC (Bos taurus)
ADP [cytosol]
L1CAM interactions (Bos taurus)
Recycling pathway of L1 (Bos taurus)
Phosphorylation of L1 by ERK (Bos taurus)
ADP [cytosol]
Phosphorylation of L1 by SRC (Bos taurus)
ADP [cytosol]
Signal transduction by L1 (Bos taurus)
Interaction of PAK1 with Rac1-GTP (Bos taurus)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Bos taurus)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Bos taurus)
ADP [cytosol]
Phosphorylation of L1 by CK-II (Bos taurus)
ADP [cytosol]
NCAM signaling for neurite out-growth (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Bos taurus)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Bos taurus)
ADP [cytosol]
Negative regulation of MAPK pathway (Bos taurus)
Negative feedback regulation of MAPK pathway (Bos taurus)
Activated MAPK phosphorylates RAF1 (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Bos taurus)
ADP [cytosol]
RAF activation (Bos taurus)
MARK3 phosphorylates KSR1 (Bos taurus)
ADP [cytosol]
Phosphorylation of RAF (Bos taurus)
ADP [cytosol]
Netrin-1 signaling (Bos taurus)
DCC mediated attractive signaling (Bos taurus)
Phosphorylation of DCC by Fyn (Bos taurus)
ADP [cytosol]
DSCAM interactions (Bos taurus)
Activation of JNK by DSCAM (Bos taurus)
ADP [cytosol]
Activation of p38MAPK by DSCAM (Bos taurus)
ADP [cytosol]
Phosphorylation and activation of Ezrin (Bos taurus)
ADP [cytosol]
RET signaling (Bos taurus)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Bos taurus)
ADP [cytosol]
RAF/MAP kinase cascade (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Bos taurus)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Bos taurus)
ADP [cytosol]
Negative regulation of MAPK pathway (Bos taurus)
Negative feedback regulation of MAPK pathway (Bos taurus)
Activated MAPK phosphorylates RAF1 (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Bos taurus)
ADP [cytosol]
RAF activation (Bos taurus)
MARK3 phosphorylates KSR1 (Bos taurus)
ADP [cytosol]
Phosphorylation of RAF (Bos taurus)
ADP [cytosol]
RET tyrosine phosphorylation (Bos taurus)
ADP [cytosol]
Reelin signalling pathway (Bos taurus)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Bos taurus)
ADP [cytosol]
Semaphorin interactions (Bos taurus)
CRMPs in Sema3A signaling (Bos taurus)
Phosphorylation of CRMPs by Cdk5 (Bos taurus)
ADP [cytosol]
Phosphorylation of CRMPs by GSK3beta (Bos taurus)
ADP [cytosol]
Tyrosine phosphorylation of CRMPs by Fes (Bos taurus)
ADP [cytosol]
Sema3A PAK dependent Axon repulsion (Bos taurus)
Autophosphorylation of PAK (Bos taurus)
ADP [cytosol]
Phosphorylation of LIMK-1 by PAK (Bos taurus)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Bos taurus)
ADP [cytosol]
Sema4D in semaphorin signaling (Bos taurus)
Sema4D induced cell migration and growth-cone collapse (Bos taurus)
SEMA4D interacts with Plexin-B1:ErbB2 (Bos taurus)
ADP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Bos taurus)
SEMA4D interacts with Plexin-B1:Met (Bos taurus)
ADP [cytosol]
Signaling by Robo receptor (Bos taurus)
Role of Abl in Robo-Slit signaling (Bos taurus)
Phosphorylation of Rob1 by Abl kinase (Bos taurus)
ADP [cytosol]
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
Regulation of TP53 Activity (Bos taurus)
Regulation of TP53 Expression and Degradation (Bos taurus)
Regulation of TP53 Degradation (Bos taurus)
AKT phosphorylates MDM2 (Bos taurus)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Bos taurus)
ADP [cytosol]
SGK1 phosphorylates MDM2 (Bos taurus)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Bos taurus)
ADP [cytosol]
TP53 Regulates Metabolic Genes (Bos taurus)
AKT phosphorylates TSC2, inhibiting it (Bos taurus)
ADP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Bos taurus)
ADP [cytosol]
TP53 Regulates Transcription of Cell Cycle Genes (Bos taurus)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Bos taurus)
PLK2 phosphorylates CENPJ (Bos taurus)
ADP [cytosol]
PLK2 phosphorylates NPM1 (Bos taurus)
ADP [cytosol]
Transcriptional regulation by RUNX3 (Bos taurus)
Regulation of RUNX3 expression and activity (Bos taurus)
SRC phosphorylates RUNX3 (Bos taurus)
ADP [cytosol]
Hemostasis (Bos taurus)
Factors involved in megakaryocyte development and platelet production (Bos taurus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Bos taurus)
ADP [cytosol]
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Bos taurus)
ADP [cytosol]
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Bos taurus)
ADP [cytosol]
Kinesins (Bos taurus)
Kinesins move along microtubules consuming ATP (Bos taurus)
ADP [cytosol]
Platelet activation, signaling and aggregation (Bos taurus)
Effects of PIP2 hydrolysis (Bos taurus)
DAG kinase produces phosphatidic acid from DAG (Bos taurus)
ADP [cytosol]
GPVI-mediated activation cascade (Bos taurus)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Bos taurus)
ADP [cytosol]
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
SYK autophosphorylates (Bos taurus)
ADP [cytosol]
Syk activation leads to SLP-76 activation (Bos taurus)
ADP [cytosol]
Syk/Lck phosphorylate LAT (Bos taurus)
ADP [cytosol]
Unknown kinase phosphorylates CLEC1B dimer:PDPN (Bos taurus)
ADP [cytosol]
Platelet Aggregation (Plug Formation) (Bos taurus)
Integrin alphaIIb beta3 signaling (Bos taurus)
Autophosphorylation of FADK1 at Y397 (Bos taurus)
ADP [cytosol]
Autophosphorylation of SRC (Bos taurus)
ADP [cytosol]
Phosphorylation of pFADK1 by SRC (Bos taurus)
ADP [cytosol]
SYK activation by SRC (Bos taurus)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Bos taurus)
Phosphorylation of p130Cas by SRC-FADK1 complex (Bos taurus)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Bos taurus)
Disinhibition of SNARE formation (Bos taurus)
Phosphorylation of Platelet Sec-1 (Bos taurus)
ADP [cytosol]
Phosphorylation of Syntaxin-4 (Bos taurus)
ADP [cytosol]
Platelet degranulation (Bos taurus)
ABCC4 accumulation of dense granule contents (Bos taurus)
ADP [cytosol]
Signal amplification (Bos taurus)
ADP signalling through P2Y purinoceptor 1 (Bos taurus)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Bos taurus)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Bos taurus)
ADP [cytosol]
Platelet homeostasis (Bos taurus)
Platelet sensitization by LDL (Bos taurus)
FGR binds and phosphorylates LRP8 (Bos taurus)
ADP [cytosol]
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Bos taurus)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Bos taurus)
ADP [cytosol]
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Bos taurus)
Transport of Antigen peptide in to ER (Bos taurus)
ADP [cytosol]
Costimulation by the CD28 family (Bos taurus)
CD28 co-stimulation (Bos taurus)
CD28 dependent PI3K/Akt signaling (Bos taurus)
AKT interacts and phosphorylates Cot (Bos taurus)
ADP [cytosol]
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
PDPK1 phosphorylates AKT at T308 (Bos taurus)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Bos taurus)
ADP [cytosol]
p-S400-Cot phosphorylates NIK (Bos taurus)
ADP [cytosol]
CD28 dependent Vav1 pathway (Bos taurus)
Activation of Vav1 (Bos taurus)
ADP [cytosol]
Phosphorylation of CD28 (Bos taurus)
ADP [cytosol]
CTLA4 inhibitory signaling (Bos taurus)
Phosphorylation of CTLA-4 (Bos taurus)
ADP [cytosol]
PD-1 signaling (Bos taurus)
Phosphorylation of PD-1 (Bos taurus)
ADP [cytosol]
MHC class II antigen presentation (Bos taurus)
Transport of antigen loaded MHC II molecules to surface (Bos taurus)
ADP [cytosol]
Rap1 signalling (Bos taurus)
PKA/PKG phosphorylate Rap1GAP2 (Bos taurus)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Bos taurus)
Downstream signaling events of B Cell Receptor (BCR) (Bos taurus)
Activation of NF-kappaB in B cells (Bos taurus)
Activated IKK phosphorylates I-kappaB (Bos taurus)
ADP [cytosol]
PRKCB (PKC-beta) phosphorylates CARMA1 (Bos taurus)
ADP [cytosol]
PIP3 activates AKT signaling (Bos taurus)
AKT phosphorylates targets in the cytosol (Bos taurus)
AKT phosphorylates AKT1S1 (PRAS40) (Bos taurus)
ADP [cytosol]
AKT phosphorylates IKKalpha (Bos taurus)
ADP [cytosol]
AKT phosphorylates MDM2 (Bos taurus)
ADP [cytosol]
AKT phosphorylates MKRN1 (Bos taurus)
ADP [cytosol]
AKT phosphorylates TSC2, inhibiting it (Bos taurus)
ADP [cytosol]
AKT phosphorylates caspase-9 (Bos taurus)
ADP [cytosol]
AKT phosphorylates p21Cip1 and p27Kip1 (Bos taurus)
ADP [cytosol]
Negative regulation of the PI3K/AKT network (Bos taurus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Bos taurus)
MAPKs phosphorylate PP2A (Bos taurus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Bos taurus)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Bos taurus)
ADP [cytosol]
PDPK1 phosphorylates AKT at T308 (Bos taurus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
PTEN Regulation (Bos taurus)
Regulation of PTEN gene transcription (Bos taurus)
mTORC1 phosphorylates MAF1 (Bos taurus)
ADP [cytosol]
Regulation of PTEN stability and activity (Bos taurus)
AKT phosphorylates MKRN1 (Bos taurus)
ADP [cytosol]
Casein kinase II phosphorylates PTEN (Bos taurus)
ADP [cytosol]
FRK phosphorylates PTEN (Bos taurus)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Bos taurus)
ADP [cytosol]
TCR signaling (Bos taurus)
Downstream TCR signaling (Bos taurus)
Activation of IKK complex (Bos taurus)
ADP [cytosol]
Activation of TAK1-TAB2 complex (Bos taurus)
ADP [cytosol]
Change of PKC theta conformation (Bos taurus)
ADP [cytosol]
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
Phosphorylation of Bcl10 (Bos taurus)
ADP [cytosol]
Phosphorylation of CARMA1 (Bos taurus)
ADP [cytosol]
Phosphorylation of PKC theta (Bos taurus)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Bos taurus)
ADP [cytosol]
Generation of second messenger molecules (Bos taurus)
Phosphorylation of PLC-gamma1 (Bos taurus)
ADP [cytosol]
Phosphorylation of SLP-76 (Bos taurus)
ADP [cytosol]
Phosphorylation of TBSMs in LAT (Bos taurus)
ADP [cytosol]
Phosphorylation of CD3 and TCR zeta chains (Bos taurus)
Activation of Lck (Bos taurus)
ADP [cytosol]
Inactivation of Lck by Csk (Bos taurus)
ADP [cytosol]
Phosphorylation of ITAM motifs in CD3 complexes (Bos taurus)
ADP [cytosol]
Translocation of ZAP-70 to Immunological synapse (Bos taurus)
Activation of ZAP-70 (Bos taurus)
ADP [cytosol]
Phosphorylation of ZAP-70 by Lck (Bos taurus)
ADP [cytosol]
Cytokine Signaling in Immune system (Bos taurus)
Growth hormone receptor signaling (Bos taurus)
JAK2 phosphorylation (Bos taurus)
ADP [cytosol]
JAK2 phosphorylation of GHR (Bos taurus)
ADP [cytosol]
Lyn activates ERK (Bos taurus)
ADP [cytosol]
Interferon Signaling (Bos taurus)
Interferon alpha/beta signaling (Bos taurus)
Activation of JAK kinases (Bos taurus)
ADP [cytosol]
Formation of p-STAT1 homodimer (Bos taurus)
ADP [cytosol]
Phosphorylation of INFAR1 by TYK2 (Bos taurus)
ADP [cytosol]
Phosphorylation of STAT2 (Bos taurus)
ADP [cytosol]
Interferon gamma signaling (Bos taurus)
Phoshorylation of STAT1 by JAK kinases (Bos taurus)
ADP [cytosol]
Phosphorylation of IFNGR1 by JAK kinases (Bos taurus)
ADP [cytosol]
Phosphorylation of JAK2 (Bos taurus)
ADP [cytosol]
Phosphorylation of STAT1 at Ser727 (Bos taurus)
ADP [cytosol]
Transphosphorylation of JAK1 (Bos taurus)
ADP [cytosol]
Prolactin receptor signaling (Bos taurus)
JAK2 phosphorylation (Bos taurus)
ADP [cytosol]
PRLR is phosphorylated at Ser-349 (Bos taurus)
ADP [cytosol]
Signaling by Interleukins (Bos taurus)
Interleukin-1 family signaling (Bos taurus)
Activated TAK1 mediates phosphorylation of the IKK Complex (Bos taurus)
ADP [cytosol]
IKBA is phosphorylated by Phospho IKKB kinase (Bos taurus)
ADP [cytosol]
IRAK4 is activated by autophosphorylation (Bos taurus)
ADP [cytosol]
IRAK4 phosphorylates IRAK1 (Bos taurus)
ADP [cytosol]
IRAK4-activated IRAK1 autophosphorylates (Bos taurus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
ADP [cytosol]
TPL2 (MAP3K8) is phosphorylated at T290 (Bos taurus)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Bos taurus)
ADP [cytosol]
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Bos taurus)
ADP [cytosol]
Interleukin-10 signaling (Bos taurus)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Bos taurus)
ADP [cytosol]
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Bos taurus)
ADP [cytosol]
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Bos taurus)
ADP [cytosol]
Interleukin-12 family signaling (Bos taurus)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Bos taurus)
ADP [cytosol]
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Bos taurus)
ADP [cytosol]
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Bos taurus)
ADP [cytosol]
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Bos taurus)
ADP [cytosol]
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Bos taurus)
ADP [cytosol]
STAT3 and STAT4 are phosphorylated by p-JAK2 and p-TYK2 after IL23:IL23R interaction (Bos taurus)
ADP [cytosol]
Interleukin-17 signaling (Bos taurus)
MAP kinase activation in TLR cascade (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
ADP [cytosol]
TPL2 (MAP3K8) is phosphorylated at T290 (Bos taurus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
ADP [cytosol]
MAPK1/MAPK3 signaling (Bos taurus)
RAF-independent MAPK1/3 activation (Bos taurus)
MAPK1 (ERK2) activation (Bos taurus)
MAP2K2 phosphorylates MAPK1 (Bos taurus)
ADP [cytosol]
MAPK3 (ERK1) activation (Bos taurus)
Inactivation of MAP2K1 by CDK1 (Bos taurus)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Bos taurus)
ADP [cytosol]
RAF/MAP kinase cascade (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Bos taurus)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Bos taurus)
ADP [cytosol]
Negative regulation of MAPK pathway (Bos taurus)
Negative feedback regulation of MAPK pathway (Bos taurus)
Activated MAPK phosphorylates RAF1 (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Bos taurus)
ADP [cytosol]
RAF activation (Bos taurus)
MARK3 phosphorylates KSR1 (Bos taurus)
ADP [cytosol]
Phosphorylation of RAF (Bos taurus)
ADP [cytosol]
Interleukin-19,20,22,24,26,28 and 29 signaling (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF-independent MAPK1/3 activation (Bos taurus)
MAPK1 (ERK2) activation (Bos taurus)
MAP2K2 phosphorylates MAPK1 (Bos taurus)
ADP [cytosol]
MAPK3 (ERK1) activation (Bos taurus)
Inactivation of MAP2K1 by CDK1 (Bos taurus)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Bos taurus)
ADP [cytosol]
RAF/MAP kinase cascade (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Bos taurus)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Bos taurus)
ADP [cytosol]
Negative regulation of MAPK pathway (Bos taurus)
Negative feedback regulation of MAPK pathway (Bos taurus)
Activated MAPK phosphorylates RAF1 (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Bos taurus)
ADP [cytosol]
RAF activation (Bos taurus)
MARK3 phosphorylates KSR1 (Bos taurus)
ADP [cytosol]
Phosphorylation of RAF (Bos taurus)
ADP [cytosol]
Interleukin-2 family signaling (Bos taurus)
Interleukin receptor SHC signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Bos taurus)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Bos taurus)
ADP [cytosol]
Negative regulation of MAPK pathway (Bos taurus)
Negative feedback regulation of MAPK pathway (Bos taurus)
Activated MAPK phosphorylates RAF1 (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Bos taurus)
ADP [cytosol]
RAF activation (Bos taurus)
MARK3 phosphorylates KSR1 (Bos taurus)
ADP [cytosol]
Phosphorylation of RAF (Bos taurus)
ADP [cytosol]
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Bos taurus)
ADP [cytosol]
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Bos taurus)
ADP [cytosol]
Recruited STAT5 is phosphorylated (Bos taurus)
ADP [cytosol]
SHC1 bound to IL2 receptor is phosphorylated (Bos taurus)
ADP [cytosol]
Within the IL-2R complex JAK3 phosphorylates JAK1 (Bos taurus)
ADP [cytosol]
Interleukin-3, 5 and GM-CSF signaling (Bos taurus)
Activation of STAT5a/b by JAK2 (Bos taurus)
ADP [cytosol]
Interleukin receptor SHC signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Bos taurus)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Bos taurus)
ADP [cytosol]
Negative regulation of MAPK pathway (Bos taurus)
Negative feedback regulation of MAPK pathway (Bos taurus)
Activated MAPK phosphorylates RAF1 (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Bos taurus)
ADP [cytosol]
RAF activation (Bos taurus)
MARK3 phosphorylates KSR1 (Bos taurus)
ADP [cytosol]
Phosphorylation of RAF (Bos taurus)
ADP [cytosol]
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Bos taurus)
ADP [cytosol]
JAK2 is phosphorylated, activated (Bos taurus)
ADP [cytosol]
Tyrosine kinases phosphorylate the receptor (Bos taurus)
ADP [cytosol]
Interleukin-4 and 13 signaling (Bos taurus)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Bos taurus)
ADP [cytosol]
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Bos taurus)
ADP [cytosol]
JAK1 phosphorylates STAT3,STAT6 (Bos taurus)
ADP [cytosol]
STAT1,STAT3,STAT6 phosphorylation (Bos taurus)
ADP [cytosol]
Interleukin-6 family signaling (Bos taurus)
IL6ST is tyrosine phosphorylated (Bos taurus)
ADP [cytosol]
JAK activation (Bos taurus)
ADP [cytosol]
PTPN11 is phosphorylated (Bos taurus)
ADP [cytosol]
Serine phosphorylation of STATs (Bos taurus)
ADP [cytosol]
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Bos taurus)
ADP [cytosol]
Interleukin-7 signaling (Bos taurus)
PI3K produces PIP3 and other phosphatidyl inositides (Bos taurus)
ADP [cytosol]
PIP3 activates AKT signaling (Bos taurus)
AKT phosphorylates targets in the cytosol (Bos taurus)
AKT phosphorylates AKT1S1 (PRAS40) (Bos taurus)
ADP [cytosol]
AKT phosphorylates IKKalpha (Bos taurus)
ADP [cytosol]
AKT phosphorylates MDM2 (Bos taurus)
ADP [cytosol]
AKT phosphorylates MKRN1 (Bos taurus)
ADP [cytosol]
AKT phosphorylates TSC2, inhibiting it (Bos taurus)
ADP [cytosol]
AKT phosphorylates caspase-9 (Bos taurus)
ADP [cytosol]
AKT phosphorylates p21Cip1 and p27Kip1 (Bos taurus)
ADP [cytosol]
Negative regulation of the PI3K/AKT network (Bos taurus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Bos taurus)
MAPKs phosphorylate PP2A (Bos taurus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Bos taurus)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Bos taurus)
ADP [cytosol]
PDPK1 phosphorylates AKT at T308 (Bos taurus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
PTEN Regulation (Bos taurus)
Regulation of PTEN gene transcription (Bos taurus)
mTORC1 phosphorylates MAF1 (Bos taurus)
ADP [cytosol]
Regulation of PTEN stability and activity (Bos taurus)
AKT phosphorylates MKRN1 (Bos taurus)
ADP [cytosol]
Casein kinase II phosphorylates PTEN (Bos taurus)
ADP [cytosol]
FRK phosphorylates PTEN (Bos taurus)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Bos taurus)
ADP [cytosol]
TNFR2 non-canonical NF-kB pathway (Bos taurus)
NIK-->noncanonical NF-kB signaling (Bos taurus)
Active NIK phosphorylates IKKA dimer (Bos taurus)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Bos taurus)
ADP [cytosol]
NIK autophosphorylates on T559 (Bos taurus)
ADP [cytosol]
Innate Immune System (Bos taurus)
Antimicrobial peptides (Bos taurus)
Ion influx/efflux at host-pathogen interface (Bos taurus)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Bos taurus)
ADP [cytosol]
C-type lectin receptors (CLRs) (Bos taurus)
CD209 (DC-SIGN) signaling (Bos taurus)
PAK phosphorylates p21 RAF1 on S338 (Bos taurus)
ADP [cytosol]
SFKs phosphorylates RAF1 on Y340,Y341 (Bos taurus)
ADP [cytosol]
CLEC7A (Dectin-1) signaling (Bos taurus)
Dectin-1 mediated noncanonical NF-kB signaling (Bos taurus)
Active NIK phosphorylates IKKA dimer (Bos taurus)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Bos taurus)
ADP [cytosol]
K63polyUb-TAK1 autophosphorylates (Bos taurus)
ADP [cytosol]
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Bos taurus)
ADP [cytosol]
PKC-delta phosphorylates CARD9 (Bos taurus)
ADP [cytosol]
SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Bos taurus)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Bos taurus)
ADP [cytosol]
Cytosolic sensors of pathogen-associated DNA (Bos taurus)
STING mediated induction of host immune responses (Bos taurus)
IRF3-mediated induction of type I IFN (Bos taurus)
IRF3 is phosphorylated by TBK1 (Bos taurus)
ADP [cytosol]
TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Bos taurus)
ADP [cytosol]
STAT6-mediated induction of chemokines (Bos taurus)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Bos taurus)
ADP [cytosol]
TBK1 phosphorylates STAT6 at Ser407 (Bos taurus)
ADP [cytosol]
p-S407-STAT6 is phosphorylated at Tyr641 (Bos taurus)
ADP [cytosol]
ZBP1(DAI) mediated induction of type I IFNs (Bos taurus)
RIP-mediated NFkB activation via ZBP1 (Bos taurus)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Bos taurus)
ADP [cytosol]
DAP12 interactions (Bos taurus)
DAP12 signaling (Bos taurus)
DAG and IP3 signaling (Bos taurus)
CaM pathway (Bos taurus)
Calmodulin induced events (Bos taurus)
PKC phosphorylates GRK2 (Bos taurus)
ADP [cytosol]
DAG stimulates protein kinase C-delta (Bos taurus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
PIP3 activates AKT signaling (Bos taurus)
AKT phosphorylates targets in the cytosol (Bos taurus)
AKT phosphorylates AKT1S1 (PRAS40) (Bos taurus)
ADP [cytosol]
AKT phosphorylates IKKalpha (Bos taurus)
ADP [cytosol]
AKT phosphorylates MDM2 (Bos taurus)
ADP [cytosol]
AKT phosphorylates MKRN1 (Bos taurus)
ADP [cytosol]
AKT phosphorylates TSC2, inhibiting it (Bos taurus)
ADP [cytosol]
AKT phosphorylates caspase-9 (Bos taurus)
ADP [cytosol]
AKT phosphorylates p21Cip1 and p27Kip1 (Bos taurus)
ADP [cytosol]
Negative regulation of the PI3K/AKT network (Bos taurus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Bos taurus)
MAPKs phosphorylate PP2A (Bos taurus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Bos taurus)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Bos taurus)
ADP [cytosol]
PDPK1 phosphorylates AKT at T308 (Bos taurus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
PTEN Regulation (Bos taurus)
Regulation of PTEN gene transcription (Bos taurus)
mTORC1 phosphorylates MAF1 (Bos taurus)
ADP [cytosol]
Regulation of PTEN stability and activity (Bos taurus)
AKT phosphorylates MKRN1 (Bos taurus)
ADP [cytosol]
Casein kinase II phosphorylates PTEN (Bos taurus)
ADP [cytosol]
FRK phosphorylates PTEN (Bos taurus)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Bos taurus)
ADP [cytosol]
Phosphorylation and activation of VAV2/VAV3 by SYK (Bos taurus)
ADP [cytosol]
Phosphorylation of BTK by p-SYK (Bos taurus)
ADP [cytosol]
Phosphorylation of LAT by p-SYK (Bos taurus)
ADP [cytosol]
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Bos taurus)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Bos taurus)
ADP [cytosol]
Phosphorylation of SYK (Bos taurus)
ADP [cytosol]
RAF/MAP kinase cascade (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Bos taurus)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Bos taurus)
ADP [cytosol]
Negative regulation of MAPK pathway (Bos taurus)
Negative feedback regulation of MAPK pathway (Bos taurus)
Activated MAPK phosphorylates RAF1 (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Bos taurus)
ADP [cytosol]
RAF activation (Bos taurus)
MARK3 phosphorylates KSR1 (Bos taurus)
ADP [cytosol]
Phosphorylation of RAF (Bos taurus)
ADP [cytosol]
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Bos taurus)
TRAF6 mediated NF-kB activation (Bos taurus)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Bos taurus)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Bos taurus)
Autophosphorylation of LYN kinase (Bos taurus)
ADP [cytosol]
FCERI mediated Ca+2 mobilization (Bos taurus)
Autophosphorylation of BTK/ITK (Bos taurus)
ADP [cytosol]
Phosphorylation of TEC kinases by p-SYK (Bos taurus)
ADP [cytosol]
FCERI mediated MAPK activation (Bos taurus)
Autophosphorylation of PAK (Bos taurus)
ADP [cytosol]
Phosphorylation and activation of VAV (Bos taurus)
ADP [cytosol]
Phosphorylation of MEK4 by MEKK1 (Bos taurus)
ADP [cytosol]
Phosphorylation of MEK7 by MEKK1 (Bos taurus)
ADP [cytosol]
Phosphorylation of SHC by SYK kinase (Bos taurus)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
RAF/MAP kinase cascade (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Bos taurus)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Bos taurus)
ADP [cytosol]
Negative regulation of MAPK pathway (Bos taurus)
Negative feedback regulation of MAPK pathway (Bos taurus)
Activated MAPK phosphorylates RAF1 (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Bos taurus)
ADP [cytosol]
RAF activation (Bos taurus)
MARK3 phosphorylates KSR1 (Bos taurus)
ADP [cytosol]
Phosphorylation of RAF (Bos taurus)
ADP [cytosol]
FCERI mediated NF-kB activation (Bos taurus)
Activation of TAK1 complex bound to pUb-TRAF6 (Bos taurus)
ADP [cytosol]
Autophosphorylation of PKC-theta (Bos taurus)
ADP [cytosol]
Phosphorylation of CARMA1 by PKC-theta (Bos taurus)
ADP [cytosol]
Phosphorylation of IKK-beta by TAK1 (Bos taurus)
ADP [cytosol]
Phosphorylation of PKC-theta (Bos taurus)
