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What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
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Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
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Data Model
Computationally inferred events
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Citing us
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H2O2 [cytosol]
Stable Identifier
R-ALL-29408
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
hydrogen peroxide
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to external stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Detoxification of Reactive Oxygen Species (Bos taurus)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Bos taurus)
H2O2 [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Bos taurus)
H2O2 [cytosol]
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
PRDX1 overoxidizes (Bos taurus)
H2O2 [cytosol]
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
FLT3 Signaling (Bos taurus)
Negative regulation of FLT3 (Bos taurus)
PTPRJ dephosphorylates active FLT3 (Bos taurus)
H2O2 [cytosol]
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Amine Oxidase reactions (Bos taurus)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Bos taurus)
MAOA:FAD oxidatively deaminates of 5HT (Bos taurus)
H2O2 [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Vitamins B6 activation to pyridoxal phosphate (Bos taurus)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Bos taurus)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Bos taurus)
H2O2 [cytosol]
AOX1 oxidises PXL to PDXate (Bos taurus)
H2O2 [cytosol]
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter clearance (Bos taurus)
Dopamine clearance from the synaptic cleft (Bos taurus)
Enzymatic degradation of Dopamine by monoamine oxidase (Bos taurus)
MAOA:FAD deaminates DA to DOPAC (Bos taurus)
H2O2 [cytosol]
Enzymatic degradation of dopamine by COMT (Bos taurus)
MAOA:FAD deaminates 3MT to HVA (Bos taurus)
H2O2 [cytosol]
Serotonin clearance from the synaptic cleft (Bos taurus)
Metabolism of serotonin (Bos taurus)
MAOA:FAD oxidatively deaminates of 5HT (Bos taurus)
H2O2 [cytosol]
Neurotransmitter release cycle (Bos taurus)
Norepinephrine Neurotransmitter Release Cycle (Bos taurus)
Metabolism of Noradrenaline (Bos taurus)
H2O2 [cytosol]
Cellular responses to external stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Detoxification of Reactive Oxygen Species (Caenorhabditis elegans)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Caenorhabditis elegans)
H2O2 [cytosol]
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Caenorhabditis elegans)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Caenorhabditis elegans)
H2O2 [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Caenorhabditis elegans)
H2O2 [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Caenorhabditis elegans)
H2O2 [cytosol]
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional Regulation by TP53 (Caenorhabditis elegans)
TP53 Regulates Metabolic Genes (Caenorhabditis elegans)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Caenorhabditis elegans)
H2O2 [cytosol]
PRDX1 overoxidizes (Caenorhabditis elegans)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Caenorhabditis elegans)
H2O2 [cytosol]
Hemostasis (Caenorhabditis elegans)
Factors involved in megakaryocyte development and platelet production (Caenorhabditis elegans)
MICAL1 produces NADP+, H2O2 (Caenorhabditis elegans)
H2O2 [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of nucleotides (Caenorhabditis elegans)
Nucleobase catabolism (Caenorhabditis elegans)
Purine catabolism (Caenorhabditis elegans)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Caenorhabditis elegans)
H2O2 [cytosol]
Hypoxanthine + H2O + O2 => Xanthine + H2O2 (Caenorhabditis elegans)
H2O2 [cytosol]
Xanthine + H2O + O2 => Urate + H2O2 (Caenorhabditis elegans)
H2O2 [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Vitamins B6 activation to pyridoxal phosphate (Caenorhabditis elegans)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Caenorhabditis elegans)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Caenorhabditis elegans)
H2O2 [cytosol]
AOX1 oxidises PXL to PDXate (Caenorhabditis elegans)
H2O2 [cytosol]
Cellular responses to external stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Detoxification of Reactive Oxygen Species (Canis familiaris)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
H2O2 [cytosol]
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Canis familiaris)
H2O2 [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
H2O2 [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Canis familiaris)
H2O2 [cytosol]
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional Regulation by TP53 (Canis familiaris)
TP53 Regulates Metabolic Genes (Canis familiaris)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
H2O2 [cytosol]
PRDX1 overoxidizes (Canis familiaris)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Canis familiaris)
H2O2 [cytosol]
Hemostasis (Canis familiaris)
Factors involved in megakaryocyte development and platelet production (Canis familiaris)
MICAL1 produces NADP+, H2O2 (Canis familiaris)
H2O2 [cytosol]
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
FLT3 Signaling (Canis familiaris)
Negative regulation of FLT3 (Canis familiaris)
PTPRJ dephosphorylates active FLT3 (Canis familiaris)
H2O2 [cytosol]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Amine Oxidase reactions (Canis familiaris)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Canis familiaris)
MAOA:FAD oxidatively deaminates of 5HT (Canis familiaris)
H2O2 [cytosol]
Metabolism of nucleotides (Canis familiaris)
Nucleobase catabolism (Canis familiaris)
Purine catabolism (Canis familiaris)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
H2O2 [cytosol]
Hypoxanthine + H2O + O2 => Xanthine + H2O2 (Canis familiaris)
H2O2 [cytosol]
Xanthine + H2O + O2 => Urate + H2O2 (Canis familiaris)
H2O2 [cytosol]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Vitamins B6 activation to pyridoxal phosphate (Canis familiaris)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Canis familiaris)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Canis familiaris)
H2O2 [cytosol]
Neuronal System (Canis familiaris)
Transmission across Chemical Synapses (Canis familiaris)
Neurotransmitter clearance (Canis familiaris)
Dopamine clearance from the synaptic cleft (Canis familiaris)
Enzymatic degradation of Dopamine by monoamine oxidase (Canis familiaris)
MAOA:FAD deaminates DA to DOPAC (Canis familiaris)
H2O2 [cytosol]
Enzymatic degradation of dopamine by COMT (Canis familiaris)
MAOA:FAD deaminates 3MT to HVA (Canis familiaris)
H2O2 [cytosol]
Serotonin clearance from the synaptic cleft (Canis familiaris)
Metabolism of serotonin (Canis familiaris)
MAOA:FAD oxidatively deaminates of 5HT (Canis familiaris)
H2O2 [cytosol]
Neurotransmitter release cycle (Canis familiaris)
Norepinephrine Neurotransmitter Release Cycle (Canis familiaris)
Metabolism of Noradrenaline (Canis familiaris)
H2O2 [cytosol]
Cellular responses to external stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Detoxification of Reactive Oxygen Species (Danio rerio)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Danio rerio)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Danio rerio)
H2O2 [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Danio rerio)
H2O2 [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Danio rerio)
H2O2 [cytosol]
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional Regulation by TP53 (Danio rerio)
TP53 Regulates Metabolic Genes (Danio rerio)
PRDX1 overoxidizes (Danio rerio)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Danio rerio)
H2O2 [cytosol]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
Amine Oxidase reactions (Danio rerio)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Danio rerio)
MAOB:FAD oxidatively deaminates TYR (Danio rerio)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates of PEA (Danio rerio)
H2O2 [cytosol]
Metabolism of nucleotides (Danio rerio)
Nucleobase catabolism (Danio rerio)
Purine catabolism (Danio rerio)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Danio rerio)
H2O2 [cytosol]
Hypoxanthine + H2O + O2 => Xanthine + H2O2 (Danio rerio)
H2O2 [cytosol]
Xanthine + H2O + O2 => Urate + H2O2 (Danio rerio)
H2O2 [cytosol]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Vitamins B6 activation to pyridoxal phosphate (Danio rerio)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Danio rerio)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Danio rerio)
H2O2 [cytosol]
AOX1 oxidises PXL to PDXate (Danio rerio)
H2O2 [cytosol]
Cellular responses to external stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Detoxification of Reactive Oxygen Species (Dictyostelium discoideum)
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Dictyostelium discoideum)
H2O2 [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Dictyostelium discoideum)
H2O2 [cytosol]
Gene expression (Transcription) (Dictyostelium discoideum)
RNA Polymerase II Transcription (Dictyostelium discoideum)
Generic Transcription Pathway (Dictyostelium discoideum)
Transcriptional Regulation by TP53 (Dictyostelium discoideum)
TP53 Regulates Metabolic Genes (Dictyostelium discoideum)
PRDX1 overoxidizes (Dictyostelium discoideum)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Dictyostelium discoideum)
H2O2 [cytosol]
Hemostasis (Dictyostelium discoideum)
Factors involved in megakaryocyte development and platelet production (Dictyostelium discoideum)
MICAL1 produces NADP+, H2O2 (Dictyostelium discoideum)
H2O2 [cytosol]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Phase I - Functionalization of compounds (Dictyostelium discoideum)
Amine Oxidase reactions (Dictyostelium discoideum)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Dictyostelium discoideum)
MAOA:FAD oxidatively deaminates of 5HT (Dictyostelium discoideum)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates TYR (Dictyostelium discoideum)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates of PEA (Dictyostelium discoideum)
H2O2 [cytosol]
Metabolism of nucleotides (Dictyostelium discoideum)
Nucleobase catabolism (Dictyostelium discoideum)
Purine catabolism (Dictyostelium discoideum)
Hypoxanthine + H2O + O2 => Xanthine + H2O2 (Dictyostelium discoideum)
H2O2 [cytosol]
Xanthine + H2O + O2 => Urate + H2O2 (Dictyostelium discoideum)
H2O2 [cytosol]
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Vitamins B6 activation to pyridoxal phosphate (Dictyostelium discoideum)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Dictyostelium discoideum)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Dictyostelium discoideum)
H2O2 [cytosol]
AOX1 oxidises PXL to PDXate (Dictyostelium discoideum)
H2O2 [cytosol]
Neuronal System (Dictyostelium discoideum)
Transmission across Chemical Synapses (Dictyostelium discoideum)
Neurotransmitter clearance (Dictyostelium discoideum)
Dopamine clearance from the synaptic cleft (Dictyostelium discoideum)
Enzymatic degradation of Dopamine by monoamine oxidase (Dictyostelium discoideum)
MAOA:FAD deaminates DA to DOPAC (Dictyostelium discoideum)
H2O2 [cytosol]
Enzymatic degradation of dopamine by COMT (Dictyostelium discoideum)
MAOA:FAD deaminates 3MT to HVA (Dictyostelium discoideum)
H2O2 [cytosol]
Serotonin clearance from the synaptic cleft (Dictyostelium discoideum)
Metabolism of serotonin (Dictyostelium discoideum)
MAOA:FAD oxidatively deaminates of 5HT (Dictyostelium discoideum)
H2O2 [cytosol]
Neurotransmitter release cycle (Dictyostelium discoideum)
Norepinephrine Neurotransmitter Release Cycle (Dictyostelium discoideum)
Metabolism of Noradrenaline (Dictyostelium discoideum)
H2O2 [cytosol]
Cellular responses to external stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Detoxification of Reactive Oxygen Species (Drosophila melanogaster)
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Drosophila melanogaster)
H2O2 [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Drosophila melanogaster)
H2O2 [cytosol]
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Metabolic Genes (Drosophila melanogaster)
PRDX1 overoxidizes (Drosophila melanogaster)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Drosophila melanogaster)
H2O2 [cytosol]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase I - Functionalization of compounds (Drosophila melanogaster)
Amine Oxidase reactions (Drosophila melanogaster)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Drosophila melanogaster)
MAOA:FAD oxidatively deaminates of 5HT (Drosophila melanogaster)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates TYR (Drosophila melanogaster)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates of PEA (Drosophila melanogaster)
H2O2 [cytosol]
Metabolism of nucleotides (Drosophila melanogaster)
Nucleobase catabolism (Drosophila melanogaster)
Purine catabolism (Drosophila melanogaster)
Hypoxanthine + H2O + O2 => Xanthine + H2O2 (Drosophila melanogaster)
H2O2 [cytosol]
Xanthine + H2O + O2 => Urate + H2O2 (Drosophila melanogaster)
H2O2 [cytosol]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Vitamins B6 activation to pyridoxal phosphate (Drosophila melanogaster)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Drosophila melanogaster)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Drosophila melanogaster)
H2O2 [cytosol]
AOX1 oxidises PXL to PDXate (Drosophila melanogaster)
H2O2 [cytosol]
Neuronal System (Drosophila melanogaster)
Transmission across Chemical Synapses (Drosophila melanogaster)
Neurotransmitter clearance (Drosophila melanogaster)
Dopamine clearance from the synaptic cleft (Drosophila melanogaster)
Enzymatic degradation of Dopamine by monoamine oxidase (Drosophila melanogaster)
MAOA:FAD deaminates DA to DOPAC (Drosophila melanogaster)
H2O2 [cytosol]
Enzymatic degradation of dopamine by COMT (Drosophila melanogaster)
MAOA:FAD deaminates 3MT to HVA (Drosophila melanogaster)
H2O2 [cytosol]
Serotonin clearance from the synaptic cleft (Drosophila melanogaster)
Metabolism of serotonin (Drosophila melanogaster)
MAOA:FAD oxidatively deaminates of 5HT (Drosophila melanogaster)
H2O2 [cytosol]
Neurotransmitter release cycle (Drosophila melanogaster)
Norepinephrine Neurotransmitter Release Cycle (Drosophila melanogaster)
Metabolism of Noradrenaline (Drosophila melanogaster)
H2O2 [cytosol]
Cellular responses to external stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Detoxification of Reactive Oxygen Species (Gallus gallus)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Gallus gallus)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Gallus gallus)
H2O2 [cytosol]
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional Regulation by TP53 (Gallus gallus)
TP53 Regulates Metabolic Genes (Gallus gallus)
PRDX1 overoxidizes (Gallus gallus)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Gallus gallus)
H2O2 [cytosol]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
Amine Oxidase reactions (Gallus gallus)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Gallus gallus)
MAOA:FAD oxidatively deaminates of 5HT (Gallus gallus)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates TYR (Gallus gallus)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates of PEA (Gallus gallus)
H2O2 [cytosol]
Metabolism of nucleotides (Gallus gallus)
Nucleobase catabolism (Gallus gallus)
Purine catabolism (Gallus gallus)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Gallus gallus)
H2O2 [cytosol]
Hypoxanthine + H2O + O2 => Xanthine + H2O2 (Gallus gallus)
H2O2 [cytosol]
Xanthine + H2O + O2 => Urate + H2O2 (Gallus gallus)
H2O2 [cytosol]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Vitamins B6 activation to pyridoxal phosphate (Gallus gallus)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Gallus gallus)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Gallus gallus)
H2O2 [cytosol]
AOX1 oxidises PXL to PDXate (Gallus gallus)
H2O2 [cytosol]
Neuronal System (Gallus gallus)
Transmission across Chemical Synapses (Gallus gallus)
Neurotransmitter clearance (Gallus gallus)
Dopamine clearance from the synaptic cleft (Gallus gallus)
Enzymatic degradation of Dopamine by monoamine oxidase (Gallus gallus)
MAOA:FAD deaminates DA to DOPAC (Gallus gallus)
H2O2 [cytosol]
Enzymatic degradation of dopamine by COMT (Gallus gallus)
MAOA:FAD deaminates 3MT to HVA (Gallus gallus)
H2O2 [cytosol]
Serotonin clearance from the synaptic cleft (Gallus gallus)
Metabolism of serotonin (Gallus gallus)
MAOA:FAD oxidatively deaminates of 5HT (Gallus gallus)
H2O2 [cytosol]
Neurotransmitter release cycle (Gallus gallus)
Norepinephrine Neurotransmitter Release Cycle (Gallus gallus)
Metabolism of Noradrenaline (Gallus gallus)
H2O2 [cytosol]
Cellular responses to external stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Detoxification of Reactive Oxygen Species (Homo sapiens)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
H2O2 [cytosol]
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
H2O2 [cytosol]
H2O2 diffuses from the mitochondrial matrix to the cytosol (Homo sapiens)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Homo sapiens)
H2O2 [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
H2O2 [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Homo sapiens)
H2O2 [cytosol]
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
FLT3 signaling in disease (Homo sapiens)
Signaling by FLT3 ITD and TKD mutants (Homo sapiens)
STAT5 activation downstream of FLT3 ITD mutants (Homo sapiens)
FLT3 ITD- and NOX4-dependent H2O2 production (Homo sapiens)
H2O2 [cytosol]
Signaling by FLT3 fusion proteins (Homo sapiens)
FLT3 ITD- and NOX4-dependent H2O2 production (Homo sapiens)
H2O2 [cytosol]
Infectious disease (Homo sapiens)
Infection with Mycobacterium tuberculosis (Homo sapiens)
Latent infection - Other responses of Mtb to phagocytosis (Homo sapiens)
Tolerance of reactive oxygen produced by macrophages (Homo sapiens)
AhpC reduces H2O2 (Homo sapiens)
H2O2 [cytosol]
H2O2 gets scavenged by unsaturated lipid (Homo sapiens)
H2O2 [cytosol]
KatG reduces H2O2 (Homo sapiens)
H2O2 [cytosol]
SodB reduces superoxide to H2O2 (Homo sapiens)
H2O2 [cytosol]
SodC reduces superoxide to H2O2 (Homo sapiens)
H2O2 [cytosol]
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Metabolic Genes (Homo sapiens)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
H2O2 [cytosol]
PRDX1 overoxidizes (Homo sapiens)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Homo sapiens)
H2O2 [cytosol]
Hemostasis (Homo sapiens)
Factors involved in megakaryocyte development and platelet production (Homo sapiens)
MICAL1 produces NADP+, H2O2 (Homo sapiens)
H2O2 [cytosol]
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
FLT3 Signaling (Homo sapiens)
Negative regulation of FLT3 (Homo sapiens)
PTPRJ dephosphorylates active FLT3 (Homo sapiens)
H2O2 [cytosol]
Innate Immune System (Homo sapiens)
ROS and RNS production in phagocytes (Homo sapiens)
Hydrogen peroxide and Fe2+ react to hydroxyl, hydroxide and Fe3+ (Homo sapiens)
H2O2 [cytosol]
Hydrogen peroxide enters the bacterium (Homo sapiens)
H2O2 [cytosol]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Amine Oxidase reactions (Homo sapiens)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Homo sapiens)
MAOA:FAD oxidatively deaminates of 5HT (Homo sapiens)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates TYR (Homo sapiens)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates of PEA (Homo sapiens)
H2O2 [cytosol]
Metabolism of nucleotides (Homo sapiens)
Nucleobase catabolism (Homo sapiens)
Purine catabolism (Homo sapiens)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
H2O2 [cytosol]
Hypoxanthine + H2O + O2 => Xanthine + H2O2 (Homo sapiens)
H2O2 [cytosol]
Xanthine + H2O + O2 => Urate + H2O2 (Homo sapiens)
H2O2 [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Vitamin C (ascorbate) metabolism (Homo sapiens)
DeHA hydrolyses to threonate and oxalate (Homo sapiens)
H2O2 [cytosol]
Vitamins B6 activation to pyridoxal phosphate (Homo sapiens)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Homo sapiens)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Homo sapiens)
H2O2 [cytosol]
AOX1 oxidises PXL to PDXate (Homo sapiens)
H2O2 [cytosol]
Metabolism of proteins (Homo sapiens)
Protein repair (Homo sapiens)
Methionine is oxidised to methionine sulfoxide (Homo sapiens)
H2O2 [cytosol]
Methionine sulfoxide is oxidised to methionine sulfone (Homo sapiens)
H2O2 [cytosol]
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter clearance (Homo sapiens)
Dopamine clearance from the synaptic cleft (Homo sapiens)
Enzymatic degradation of Dopamine by monoamine oxidase (Homo sapiens)
MAOA:FAD deaminates DA to DOPAC (Homo sapiens)
H2O2 [cytosol]
Enzymatic degradation of dopamine by COMT (Homo sapiens)
MAOA:FAD deaminates 3MT to HVA (Homo sapiens)
H2O2 [cytosol]
Serotonin clearance from the synaptic cleft (Homo sapiens)
Metabolism of serotonin (Homo sapiens)
MAOA:FAD oxidatively deaminates of 5HT (Homo sapiens)
H2O2 [cytosol]
Neurotransmitter release cycle (Homo sapiens)
Norepinephrine Neurotransmitter Release Cycle (Homo sapiens)
Metabolism of Noradrenaline (Homo sapiens)
H2O2 [cytosol]
Cellular responses to external stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Detoxification of Reactive Oxygen Species (Mus musculus)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
H2O2 [cytosol]
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Mus musculus)
H2O2 [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
H2O2 [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Mus musculus)
H2O2 [cytosol]
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
TP53 Regulates Metabolic Genes (Mus musculus)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
H2O2 [cytosol]
PRDX1 overoxidizes (Mus musculus)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Mus musculus)
H2O2 [cytosol]
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
FLT3 Signaling (Mus musculus)
Negative regulation of FLT3 (Mus musculus)
PTPRJ dephosphorylates active FLT3 (Mus musculus)
H2O2 [cytosol]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Amine Oxidase reactions (Mus musculus)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Mus musculus)
MAOA:FAD oxidatively deaminates of 5HT (Mus musculus)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates TYR (Mus musculus)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates of PEA (Mus musculus)
H2O2 [cytosol]
Metabolism of nucleotides (Mus musculus)
Nucleobase catabolism (Mus musculus)
Purine catabolism (Mus musculus)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
H2O2 [cytosol]
Hypoxanthine + H2O + O2 => Xanthine + H2O2 (Mus musculus)
H2O2 [cytosol]
Xanthine + H2O + O2 => Urate + H2O2 (Mus musculus)
H2O2 [cytosol]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Vitamins B6 activation to pyridoxal phosphate (Mus musculus)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Mus musculus)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Mus musculus)
H2O2 [cytosol]
AOX1 oxidises PXL to PDXate (Mus musculus)
H2O2 [cytosol]
Neuronal System (Mus musculus)
Transmission across Chemical Synapses (Mus musculus)
Neurotransmitter clearance (Mus musculus)
Dopamine clearance from the synaptic cleft (Mus musculus)
Enzymatic degradation of Dopamine by monoamine oxidase (Mus musculus)
MAOA:FAD deaminates DA to DOPAC (Mus musculus)
H2O2 [cytosol]
Enzymatic degradation of dopamine by COMT (Mus musculus)
MAOA:FAD deaminates 3MT to HVA (Mus musculus)
H2O2 [cytosol]
Serotonin clearance from the synaptic cleft (Mus musculus)
Metabolism of serotonin (Mus musculus)
MAOA:FAD oxidatively deaminates of 5HT (Mus musculus)
H2O2 [cytosol]
Neurotransmitter release cycle (Mus musculus)
Norepinephrine Neurotransmitter Release Cycle (Mus musculus)
Metabolism of Noradrenaline (Mus musculus)
H2O2 [cytosol]
Cellular responses to external stimuli (Plasmodium falciparum)
Cellular responses to stress (Plasmodium falciparum)
Detoxification of Reactive Oxygen Species (Plasmodium falciparum)
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Plasmodium falciparum)
H2O2 [cytosol]
Gene expression (Transcription) (Plasmodium falciparum)
RNA Polymerase II Transcription (Plasmodium falciparum)
Generic Transcription Pathway (Plasmodium falciparum)
Transcriptional Regulation by TP53 (Plasmodium falciparum)
TP53 Regulates Metabolic Genes (Plasmodium falciparum)
PRDX1 overoxidizes (Plasmodium falciparum)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Plasmodium falciparum)
H2O2 [cytosol]
Cellular responses to external stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Detoxification of Reactive Oxygen Species (Rattus norvegicus)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
H2O2 [cytosol]
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Rattus norvegicus)
H2O2 [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
H2O2 [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Rattus norvegicus)
H2O2 [cytosol]
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
TP53 Regulates Metabolic Genes (Rattus norvegicus)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
H2O2 [cytosol]
PRDX1 overoxidizes (Rattus norvegicus)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Rattus norvegicus)
H2O2 [cytosol]
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
FLT3 Signaling (Rattus norvegicus)
Negative regulation of FLT3 (Rattus norvegicus)
PTPRJ dephosphorylates active FLT3 (Rattus norvegicus)
H2O2 [cytosol]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Amine Oxidase reactions (Rattus norvegicus)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Rattus norvegicus)
MAOA:FAD oxidatively deaminates of 5HT (Rattus norvegicus)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates TYR (Rattus norvegicus)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates of PEA (Rattus norvegicus)
H2O2 [cytosol]
Metabolism of nucleotides (Rattus norvegicus)
Nucleobase catabolism (Rattus norvegicus)
Purine catabolism (Rattus norvegicus)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
H2O2 [cytosol]
Hypoxanthine + H2O + O2 => Xanthine + H2O2 (Rattus norvegicus)
H2O2 [cytosol]
Xanthine + H2O + O2 => Urate + H2O2 (Rattus norvegicus)
H2O2 [cytosol]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Vitamins B6 activation to pyridoxal phosphate (Rattus norvegicus)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Rattus norvegicus)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Rattus norvegicus)
H2O2 [cytosol]
AOX1 oxidises PXL to PDXate (Rattus norvegicus)
H2O2 [cytosol]
Neuronal System (Rattus norvegicus)
Transmission across Chemical Synapses (Rattus norvegicus)
Neurotransmitter clearance (Rattus norvegicus)
Dopamine clearance from the synaptic cleft (Rattus norvegicus)
Enzymatic degradation of Dopamine by monoamine oxidase (Rattus norvegicus)
MAOA:FAD deaminates DA to DOPAC (Rattus norvegicus)
H2O2 [cytosol]
Enzymatic degradation of dopamine by COMT (Rattus norvegicus)
MAOA:FAD deaminates 3MT to HVA (Rattus norvegicus)
H2O2 [cytosol]
Serotonin clearance from the synaptic cleft (Rattus norvegicus)
Metabolism of serotonin (Rattus norvegicus)
MAOA:FAD oxidatively deaminates of 5HT (Rattus norvegicus)
H2O2 [cytosol]
Neurotransmitter release cycle (Rattus norvegicus)
Norepinephrine Neurotransmitter Release Cycle (Rattus norvegicus)
Metabolism of Noradrenaline (Rattus norvegicus)
H2O2 [cytosol]
Cellular responses to external stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Detoxification of Reactive Oxygen Species (Saccharomyces cerevisiae)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Saccharomyces cerevisiae)
H2O2 [cytosol]
Gene expression (Transcription) (Saccharomyces cerevisiae)
RNA Polymerase II Transcription (Saccharomyces cerevisiae)
Generic Transcription Pathway (Saccharomyces cerevisiae)
Transcriptional Regulation by TP53 (Saccharomyces cerevisiae)
TP53 Regulates Metabolic Genes (Saccharomyces cerevisiae)
PRDX1 overoxidizes (Saccharomyces cerevisiae)
H2O2 [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of water-soluble vitamins and cofactors (Saccharomyces cerevisiae)
Vitamins B6 activation to pyridoxal phosphate (Saccharomyces cerevisiae)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Saccharomyces cerevisiae)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Saccharomyces cerevisiae)
H2O2 [cytosol]
Cellular responses to external stimuli (Schizosaccharomyces pombe)
Cellular responses to stress (Schizosaccharomyces pombe)
Detoxification of Reactive Oxygen Species (Schizosaccharomyces pombe)
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Schizosaccharomyces pombe)
H2O2 [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Schizosaccharomyces pombe)
H2O2 [cytosol]
Gene expression (Transcription) (Schizosaccharomyces pombe)
RNA Polymerase II Transcription (Schizosaccharomyces pombe)
Generic Transcription Pathway (Schizosaccharomyces pombe)
Transcriptional Regulation by TP53 (Schizosaccharomyces pombe)
TP53 Regulates Metabolic Genes (Schizosaccharomyces pombe)
PRDX1 overoxidizes (Schizosaccharomyces pombe)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Schizosaccharomyces pombe)
H2O2 [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of water-soluble vitamins and cofactors (Schizosaccharomyces pombe)
Vitamins B6 activation to pyridoxal phosphate (Schizosaccharomyces pombe)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Schizosaccharomyces pombe)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Schizosaccharomyces pombe)
H2O2 [cytosol]
Cellular responses to external stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Detoxification of Reactive Oxygen Species (Sus scrofa)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
H2O2 [cytosol]
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Sus scrofa)
H2O2 [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
H2O2 [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Sus scrofa)
H2O2 [cytosol]
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
TP53 Regulates Metabolic Genes (Sus scrofa)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
H2O2 [cytosol]
PRDX1 overoxidizes (Sus scrofa)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Sus scrofa)
H2O2 [cytosol]
Hemostasis (Sus scrofa)
Factors involved in megakaryocyte development and platelet production (Sus scrofa)
MICAL1 produces NADP+, H2O2 (Sus scrofa)
H2O2 [cytosol]
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
FLT3 Signaling (Sus scrofa)
Negative regulation of FLT3 (Sus scrofa)
PTPRJ dephosphorylates active FLT3 (Sus scrofa)
H2O2 [cytosol]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Amine Oxidase reactions (Sus scrofa)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Sus scrofa)
MAOB:FAD oxidatively deaminates TYR (Sus scrofa)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates of PEA (Sus scrofa)
H2O2 [cytosol]
Metabolism of nucleotides (Sus scrofa)
Nucleobase catabolism (Sus scrofa)
Purine catabolism (Sus scrofa)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
H2O2 [cytosol]
Hypoxanthine + H2O + O2 => Xanthine + H2O2 (Sus scrofa)
H2O2 [cytosol]
Xanthine + H2O + O2 => Urate + H2O2 (Sus scrofa)
H2O2 [cytosol]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Vitamins B6 activation to pyridoxal phosphate (Sus scrofa)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Sus scrofa)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Sus scrofa)
H2O2 [cytosol]
AOX1 oxidises PXL to PDXate (Sus scrofa)
H2O2 [cytosol]
Cellular responses to external stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Detoxification of Reactive Oxygen Species (Xenopus tropicalis)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Xenopus tropicalis)
H2O2 [cytosol]
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Xenopus tropicalis)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Xenopus tropicalis)
H2O2 [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Xenopus tropicalis)
H2O2 [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Xenopus tropicalis)
H2O2 [cytosol]
Gene expression (Transcription) (Xenopus tropicalis)
RNA Polymerase II Transcription (Xenopus tropicalis)
Generic Transcription Pathway (Xenopus tropicalis)
Transcriptional Regulation by TP53 (Xenopus tropicalis)
TP53 Regulates Metabolic Genes (Xenopus tropicalis)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Xenopus tropicalis)
H2O2 [cytosol]
PRDX1 overoxidizes (Xenopus tropicalis)
H2O2 [cytosol]
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Xenopus tropicalis)
H2O2 [cytosol]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase I - Functionalization of compounds (Xenopus tropicalis)
Amine Oxidase reactions (Xenopus tropicalis)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Xenopus tropicalis)
MAOB:FAD oxidatively deaminates TYR (Xenopus tropicalis)
H2O2 [cytosol]
MAOB:FAD oxidatively deaminates of PEA (Xenopus tropicalis)
H2O2 [cytosol]
Metabolism of nucleotides (Xenopus tropicalis)
Nucleobase catabolism (Xenopus tropicalis)
Purine catabolism (Xenopus tropicalis)
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Xenopus tropicalis)
H2O2 [cytosol]
Hypoxanthine + H2O + O2 => Xanthine + H2O2 (Xenopus tropicalis)
H2O2 [cytosol]
Xanthine + H2O + O2 => Urate + H2O2 (Xenopus tropicalis)
H2O2 [cytosol]
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of water-soluble vitamins and cofactors (Xenopus tropicalis)
Vitamins B6 activation to pyridoxal phosphate (Xenopus tropicalis)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Xenopus tropicalis)
H2O2 [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Xenopus tropicalis)
H2O2 [cytosol]
AOX1 oxidises PXL to PDXate (Xenopus tropicalis)
H2O2 [cytosol]
External Reference Information
External Reference
hydrogen peroxide [ChEBI:16240]
Participant Of
input
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
AhpC reduces H2O2
DeHA hydrolyses to threonate and oxalate
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
H2O2 gets scavenged by unsaturated lipid
Hydrogen peroxide and Fe2+ react to hydroxyl, hydroxide and Fe3+
KatG reduces H2O2
Methionine is oxidised to methionine sulfoxide
Methionine sulfoxide is oxidised to methionine sulfone
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1 overoxidizes
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O
output
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PDXP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
2xPNPO:2xFMN oxidizes PXAP to PXLP
AOX1 oxidises PXL to PDXate
AOX1 oxidises PXL to PDXate
AOX1 oxidises PXL to PDXate
AOX1 oxidises PXL to PDXate
AOX1 oxidises PXL to PDXate
AOX1 oxidises PXL to PDXate
AOX1 oxidises PXL to PDXate
AOX1 oxidises PXL to PDXate
AOX1 oxidises PXL to PDXate
AOX1 oxidises PXL to PDXate
AOX1 oxidises PXL to PDXate
FLT3 ITD- and NOX4-dependent H2O2 production
H2O2 diffuses from the mitochondrial matrix to the cytosol
H2O2 diffuses from the mitochondrial matrix to the cytosol
Hydrogen peroxide enters the bacterium
Hypoxanthine + H2O + O2 => Xanthine + H2O2
Hypoxanthine + H2O + O2 => Xanthine + H2O2
Hypoxanthine + H2O + O2 => Xanthine + H2O2
Hypoxanthine + H2O + O2 => Xanthine + H2O2
Hypoxanthine + H2O + O2 => Xanthine + H2O2
Hypoxanthine + H2O + O2 => Xanthine + H2O2
Hypoxanthine + H2O + O2 => Xanthine + H2O2
Hypoxanthine + H2O + O2 => Xanthine + H2O2
Hypoxanthine + H2O + O2 => Xanthine + H2O2
Hypoxanthine + H2O + O2 => Xanthine + H2O2
Hypoxanthine + H2O + O2 => Xanthine + H2O2
MAOA:FAD deaminates 3MT to HVA
MAOA:FAD deaminates 3MT to HVA
MAOA:FAD deaminates 3MT to HVA
MAOA:FAD deaminates 3MT to HVA
MAOA:FAD deaminates 3MT to HVA
MAOA:FAD deaminates 3MT to HVA
MAOA:FAD deaminates 3MT to HVA
MAOA:FAD deaminates 3MT to HVA
MAOA:FAD deaminates DA to DOPAC
MAOA:FAD deaminates DA to DOPAC
MAOA:FAD deaminates DA to DOPAC
MAOA:FAD deaminates DA to DOPAC
MAOA:FAD deaminates DA to DOPAC
MAOA:FAD deaminates DA to DOPAC
MAOA:FAD deaminates DA to DOPAC
MAOA:FAD deaminates DA to DOPAC
MAOA:FAD oxidatively deaminates of 5HT
MAOA:FAD oxidatively deaminates of 5HT
MAOA:FAD oxidatively deaminates of 5HT
MAOA:FAD oxidatively deaminates of 5HT
MAOA:FAD oxidatively deaminates of 5HT
MAOA:FAD oxidatively deaminates of 5HT
MAOA:FAD oxidatively deaminates of 5HT
MAOA:FAD oxidatively deaminates of 5HT
MAOB:FAD oxidatively deaminates of PEA
MAOB:FAD oxidatively deaminates of PEA
MAOB:FAD oxidatively deaminates of PEA
MAOB:FAD oxidatively deaminates of PEA
MAOB:FAD oxidatively deaminates of PEA
MAOB:FAD oxidatively deaminates of PEA
MAOB:FAD oxidatively deaminates of PEA
MAOB:FAD oxidatively deaminates of PEA
MAOB:FAD oxidatively deaminates of PEA
MAOB:FAD oxidatively deaminates TYR
MAOB:FAD oxidatively deaminates TYR
MAOB:FAD oxidatively deaminates TYR
MAOB:FAD oxidatively deaminates TYR
MAOB:FAD oxidatively deaminates TYR
MAOB:FAD oxidatively deaminates TYR
MAOB:FAD oxidatively deaminates TYR
MAOB:FAD oxidatively deaminates TYR
MAOB:FAD oxidatively deaminates TYR
Metabolism of Noradrenaline
Metabolism of Noradrenaline
Metabolism of Noradrenaline
Metabolism of Noradrenaline
Metabolism of Noradrenaline
Metabolism of Noradrenaline
Metabolism of Noradrenaline
Metabolism of Noradrenaline
MICAL1 produces NADP+, H2O2
MICAL1 produces NADP+, H2O2
MICAL1 produces NADP+, H2O2
MICAL1 produces NADP+, H2O2
MICAL1 produces NADP+, H2O2
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
SodB reduces superoxide to H2O2
SodC reduces superoxide to H2O2
Xanthine + H2O + O2 => Urate + H2O2
Xanthine + H2O + O2 => Urate + H2O2
Xanthine + H2O + O2 => Urate + H2O2
Xanthine + H2O + O2 => Urate + H2O2
Xanthine + H2O + O2 => Urate + H2O2
Xanthine + H2O + O2 => Urate + H2O2
Xanthine + H2O + O2 => Urate + H2O2
Xanthine + H2O + O2 => Urate + H2O2
Xanthine + H2O + O2 => Urate + H2O2
Xanthine + H2O + O2 => Urate + H2O2
Xanthine + H2O + O2 => Urate + H2O2
This entity regulates
Negatively
PTPRJ dephosphorylates active FLT3
Other forms of this molecule
H2O2 [cytoplasm]
H2O2 [phagocytic vesicle lumen]
H2O2 [peroxisomal matrix]
H2O2 [mitochondrial intermembrane space]
H2O2 [extracellular region]
H2O2 [endoplasmic reticulum lumen]
H2O2 [mitochondrial matrix]
Cross References
COMPOUND
C00027
PubChem Substance
11533079
HMDB Metabolite
HMDB0003125
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![H2O2 [cytosol] icon](/icon/R-ICO-012842.svg){kind=icon}
